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Commentary on "identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array." Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, Røder MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC; COGS-Cancer Research UK GWAS-ELLIPSE (part of GAME-ON) Initiative; Australian Prostate Cancer Bioresource; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT (Prostate testing for cancer and Treatment) Study Olumi AF et al. Urol Oncol. (2014)

Results: 1 to 20 of 211


Proteome Analysis of the Triton-Insoluble Erythrocyte Membrane Skeleton.

Basu A, Harper S, Pesciotta EN, Speicher KD, Chakrabarti A, Speicher DW.

J Proteomics. 2015 Aug 10. pii: S1874-3919(15)30095-6. doi: 10.1016/j.jprot.2015.08.004. [Epub ahead of print]


Prevalence and Predictors of Adverse Events during Procedural Sedation Anesthesia-Outside the Operating Room for Esophagogastroduodenoscopy and Colonoscopy in Children: Age Is an Independent Predictor of Outcomes.

Biber JL, Allareddy V, Allareddy V, Gallagher SM, Couloures KG, Speicher DG, Cravero JP, Stormorken AG.

Pediatr Crit Care Med. 2015 Jul 24. [Epub ahead of print]


Corrigendum: Landscape of the mitochondrial Hsp90 metabolome in tumours.

Chae YC, Angelin A, Lisanti S, Kossenkov AV, Speicher KD, Wang H, Powers JF, Tischler AS, Pacak K, Fliedner S, Michalek RD, Karoly ED, Wallace DC, Languino LR, Speicher DW, Altieri DC.

Nat Commun. 2015 Jun 18;6:7605. doi: 10.1038/ncomms8605. No abstract available.


Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays.

Olia AS, Barker K, McCullough CE, Tang HY, Speicher DW, Qiu J, LaBaer J, Marmorstein R.

ACS Chem Biol. 2015 Jun 23. [Epub ahead of print]


The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap.

Brown JW, Bullitt E, Sriswasdi S, Harper S, Speicher DW, McKnight CJ.

PLoS Comput Biol. 2015 Jun 11;11(6):e1004302. doi: 10.1371/journal.pcbi.1004302. eCollection 2015 Jun.


Probing structures of large protein complexes using zero-length cross-linking.

Rivera-Santiago RF, Sriswasdi S, Harper SL, Speicher DW.

Methods. 2015 May 1. pii: S1046-2023(15)00178-4. doi: 10.1016/j.ymeth.2015.04.031. [Epub ahead of print] Review.


Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.

Bengsch F, Tu Z, Tang HY, Zhu H, Speicher DW, Zhang R.

Cell Cycle. 2015;14(10):1540-7. doi: 10.1080/15384101.2015.1026492.


Solution structure of the reduced form of human peroxiredoxin-6 elucidated using zero-length chemical cross-linking and homology modelling.

Rivera-Santiago RF, Harper SL, Zhou S, Sriswasdi S, Feinstein SI, Fisher AB, Speicher DW.

Biochem J. 2015 May 15;468(1):87-98. doi: 10.1042/BJ20141463.


Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers.

Bitler BG, Aird KM, Garipov A, Li H, Amatangelo M, Kossenkov AV, Schultz DC, Liu Q, Shih IeM, Conejo-Garcia JR, Speicher DW, Zhang R.

Nat Med. 2015 Mar;21(3):231-8. doi: 10.1038/nm.3799. Epub 2015 Feb 16.


Identification of secreted proteins that reflect autophagy dynamics within tumor cells.

Kraya AA, Piao S, Xu X, Zhang G, Herlyn M, Gimotty P, Levine B, Amaravadi RK, Speicher DW.

Autophagy. 2015;11(1):60-74. doi: 10.4161/15548627.2014.984273.


Spectrin tetramer formation is not required for viable development in Drosophila.

Khanna MR, Mattie FJ, Browder KC, Radyk MD, Crilly SE, Bakerink KJ, Harper SL, Speicher DW, Thomas GH.

J Biol Chem. 2015 Jan 9;290(2):706-15. doi: 10.1074/jbc.M114.615427. Epub 2014 Nov 7.


Would the Use of Bedside Bladder Ultrasound Decrease the Necessity of Invasive Bladder Catheterization in the Pediatric Intensive Care Unit?

Wheeler J, O'Riordan M, Allareddy V, Speicher D.

Clin Pediatr (Phila). 2015 Jul;54(8):800-2. doi: 10.1177/0009922814547566. Epub 2014 Aug 19. No abstract available.


Hospital based emergency department visits attributed to child physical abuse in United States: predictors of in-hospital mortality.

Allareddy V, Asad R, Lee MK, Nalliah RP, Rampa S, Speicher DG, Rotta AT, Allareddy V.

PLoS One. 2014 Jun 11;9(2):e100110. doi: 10.1371/journal.pone.0100110. eCollection 2014.


LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase.

Peng H, Talebzadeh-Farrooji M, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, Carolin AS, Speicher DW, Skordalakes E, Huang Q, Dedhar S, Borden KL, Rauscher FJ 3rd.

Cancer Res. 2014 Mar 1;74(5):1390-403. doi: 10.1158/0008-5472.CAN-13-1275.


Dysferlin and other non-red cell proteins accumulate in the red cell membrane of Diamond-Blackfan Anemia patients.

Pesciotta EN, Sriswasdi S, Tang HY, Speicher DW, Mason PJ, Bessler M.

PLoS One. 2014 Jan 14;9(1):e85504. doi: 10.1371/journal.pone.0085504. eCollection 2014.


Probing large conformational rearrangements in wild-type and mutant spectrin using structural mass spectrometry.

Sriswasdi S, Harper SL, Tang HY, Gallagher PG, Speicher DW.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1801-6. doi: 10.1073/pnas.1317620111. Epub 2014 Jan 22.


Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells.

Swift J, Harada T, Buxboim A, Shin JW, Tang HY, Speicher DW, Discher DE.

Nucleus. 2013 Nov-Dec;4(6):450-9. doi: 10.4161/nucl.27413. Epub 2013 Dec 6.


Enhanced identification of zero-length chemical cross-links using label-free quantitation and high-resolution fragment ion spectra.

Sriswasdi S, Harper SL, Tang HY, Speicher DW.

J Proteome Res. 2014 Feb 7;13(2):898-914. doi: 10.1021/pr400953w. Epub 2014 Jan 7.


Serial cervicovaginal exposures with replication-deficient SIVsm induce higher dendritic cell (pDC) and CD4+ T-cell infiltrates not associated with prevention but a more severe SIVmac251 infection of rhesus macaques.

Abdulhaqq SA, Martinez MI, Kang G, Foulkes AS, Rodriguez IV, Nichols SM, Hunter M, Sariol CA, Ruiz LA, Ross BN, Yin X, Speicher DW, Haase AT, Marx PA, Li Q, Kraiselburd EN, Montaner LJ.

J Acquir Immune Defic Syndr. 2014 Apr 1;65(4):405-13. doi: 10.1097/QAI.0000000000000047.


Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma.

Villanueva J, Infante JR, Krepler C, Reyes-Uribe P, Samanta M, Chen HY, Li B, Swoboda RK, Wilson M, Vultur A, Fukunaba-Kalabis M, Wubbenhorst B, Chen TY, Liu Q, Sproesser K, DeMarini DJ, Gilmer TM, Martin AM, Marmorstein R, Schultz DC, Speicher DW, Karakousis GC, Xu W, Amaravadi RK, Xu X, Schuchter LM, Herlyn M, Nathanson KL.

Cell Rep. 2013 Sep 26;4(6):1090-9. doi: 10.1016/j.celrep.2013.08.023. Epub 2013 Sep 19.

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