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Commentary on "identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array." Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, Røder MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC; COGS-Cancer Research UK GWAS-ELLIPSE (part of GAME-ON) Initiative; Australian Prostate Cancer Bioresource; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT (Prostate testing for cancer and Treatment) Study Olumi AF et al. Urol Oncol. (2014)

Results: 1 to 20 of 200

1.

Would the Use of Bedside Bladder Ultrasound Decrease the Necessity of Invasive Bladder Catheterization in the Pediatric Intensive Care Unit?

Wheeler J, O'Riordan M, Allareddy V, Speicher D.

Clin Pediatr (Phila). 2014 Aug 19. pii: 0009922814547566. [Epub ahead of print] No abstract available.

PMID:
25139663
[PubMed - as supplied by publisher]
2.

Hospital based emergency department visits attributed to child physical abuse in United States: predictors of in-hospital mortality.

Allareddy V, Asad R, Lee MK, Nalliah RP, Rampa S, Speicher DG, Rotta AT, Allareddy V.

PLoS One. 2014 Jun 11;9(2):e100110. doi: 10.1371/journal.pone.0100110. eCollection 2014.

PMID:
24919088
[PubMed - in process]
Free PMC Article
3.

LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase.

Peng H, Talebzadeh-Farrooji M, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, Carolin AS, Speicher DW, Skordalakes E, Huang Q, Dedhar S, Borden KL, Rauscher FJ 3rd.

Cancer Res. 2014 Mar 1;74(5):1390-403. doi: 10.1158/0008-5472.CAN-13-1275.

PMID:
24590809
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Dysferlin and other non-red cell proteins accumulate in the red cell membrane of Diamond-Blackfan Anemia patients.

Pesciotta EN, Sriswasdi S, Tang HY, Speicher DW, Mason PJ, Bessler M.

PLoS One. 2014 Jan 14;9(1):e85504. doi: 10.1371/journal.pone.0085504. eCollection 2014.

PMID:
24454878
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Probing large conformational rearrangements in wild-type and mutant spectrin using structural mass spectrometry.

Sriswasdi S, Harper SL, Tang HY, Gallagher PG, Speicher DW.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1801-6. doi: 10.1073/pnas.1317620111. Epub 2014 Jan 22.

PMID:
24453214
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells.

Swift J, Harada T, Buxboim A, Shin JW, Tang HY, Speicher DW, Discher DE.

Nucleus. 2013 Nov-Dec;4(6):450-9. doi: 10.4161/nucl.27413. Epub 2013 Dec 6.

PMID:
24448480
[PubMed - indexed for MEDLINE]
7.

Enhanced identification of zero-length chemical cross-links using label-free quantitation and high-resolution fragment ion spectra.

Sriswasdi S, Harper SL, Tang HY, Speicher DW.

J Proteome Res. 2014 Feb 7;13(2):898-914. doi: 10.1021/pr400953w. Epub 2014 Jan 7.

PMID:
24369724
[PubMed - in process]
8.

Serial cervicovaginal exposures with replication-deficient SIVsm induce higher dendritic cell (pDC) and CD4+ T-cell infiltrates not associated with prevention but a more severe SIVmac251 infection of rhesus macaques.

Abdulhaqq SA, Martinez MI, Kang G, Foulkes AS, Rodriguez IV, Nichols SM, Hunter M, Sariol CA, Ruiz LA, Ross BN, Yin X, Speicher DW, Haase AT, Marx PA, Li Q, Kraiselburd EN, Montaner LJ.

J Acquir Immune Defic Syndr. 2014 Apr 1;65(4):405-13. doi: 10.1097/QAI.0000000000000047.

PMID:
24226059
[PubMed - indexed for MEDLINE]
9.

Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma.

Villanueva J, Infante JR, Krepler C, Reyes-Uribe P, Samanta M, Chen HY, Li B, Swoboda RK, Wilson M, Vultur A, Fukunaba-Kalabis M, Wubbenhorst B, Chen TY, Liu Q, Sproesser K, DeMarini DJ, Gilmer TM, Martin AM, Marmorstein R, Schultz DC, Speicher DW, Karakousis GC, Xu W, Amaravadi RK, Xu X, Schuchter LM, Herlyn M, Nathanson KL.

Cell Rep. 2013 Sep 26;4(6):1090-9. doi: 10.1016/j.celrep.2013.08.023. Epub 2013 Sep 19.

PMID:
24055054
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target.

Rasanen K, Sriswasdi S, Valiga A, Tang HY, Zhang G, Perego M, Somasundaram R, Li L, Speicher K, Klein-Szanto AJ, Basu D, Rustgi AK, Speicher DW, Herlyn M.

Mol Cell Proteomics. 2013 Dec;12(12):3778-92. doi: 10.1074/mcp.M113.029587. Epub 2013 Sep 13.

PMID:
24037664
[PubMed - indexed for MEDLINE]
11.

Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.

Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PC, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, Rehfeldt F, Speicher DW, Discher DE.

Science. 2013 Aug 30;341(6149):1240104. doi: 10.1126/science.1240104.

PMID:
23990565
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step.

Gumireddy K, Li A, Yan J, Setoyama T, Johannes GJ, Orom UA, Tchou J, Liu Q, Zhang L, Speicher DW, Calin GA, Huang Q.

EMBO J. 2013 Oct 16;32(20):2672-84. doi: 10.1038/emboj.2013.188. Epub 2013 Aug 23.

PMID:
23974796
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation.

Harper SL, Sriswasdi S, Tang HY, Gaetani M, Gallagher PG, Speicher DW.

Blood. 2013 Oct 24;122(17):3045-53. doi: 10.1182/blood-2013-02-487702. Epub 2013 Aug 23.

PMID:
23974198
[PubMed - indexed for MEDLINE]
14.

Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration.

Garland DL, Fernandez-Godino R, Kaur I, Speicher KD, Harnly JM, Lambris JD, Speicher DW, Pierce EA.

Hum Mol Genet. 2014 Jan 1;23(1):52-68. doi: 10.1093/hmg/ddt395. Epub 2013 Aug 13.

PMID:
23943789
[PubMed - indexed for MEDLINE]
15.

Landscape of the mitochondrial Hsp90 metabolome in tumours.

Chae YC, Angelin A, Lisanti S, Kossenkov AV, Speicher KD, Wang H, Powers JF, Tischler AS, Pacak K, Fliedner S, Michalek RD, Karoly ED, Wallace DC, Languino LR, Speicher DW, Altieri DC.

Nat Commun. 2013;4:2139. doi: 10.1038/ncomms3139.

PMID:
23842546
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer.

Tang HY, Beer LA, Tanyi JL, Zhang R, Liu Q, Speicher DW.

J Proteomics. 2013 Aug 26;89:165-78. doi: 10.1016/j.jprot.2013.06.016. Epub 2013 Jun 21.

PMID:
23792823
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells.

Roesch A, Vultur A, Bogeski I, Wang H, Zimmermann KM, Speicher D, Körbel C, Laschke MW, Gimotty PA, Philipp SE, Krause E, Pätzold S, Villanueva J, Krepler C, Fukunaga-Kalabis M, Hoth M, Bastian BC, Vogt T, Herlyn M.

Cancer Cell. 2013 Jun 10;23(6):811-25. doi: 10.1016/j.ccr.2013.05.003.

PMID:
23764003
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition.

Amatangelo MD, Garipov A, Li H, Conejo-Garcia JR, Speicher DW, Zhang R.

Cell Cycle. 2013 Jul 1;12(13):2113-9. doi: 10.4161/cc.25163. Epub 2013 Jun 10.

PMID:
23759589
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Identification of multiple novel protein biomarkers shed by human serous ovarian tumors into the blood of immunocompromised mice and verified in patient sera.

Beer LA, Wang H, Tang HY, Cao Z, Chang-Wong T, Tanyi JL, Zhang R, Liu Q, Speicher DW.

PLoS One. 2013;8(3):e60129. doi: 10.1371/journal.pone.0060129. Epub 2013 Mar 27.

PMID:
23544127
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance.

Mason M, Wanat JJ, Harper S, Schultz DC, Speicher DW, Johnson FB, Skordalakes E.

Structure. 2013 Jan 8;21(1):109-20. doi: 10.1016/j.str.2012.10.012. Epub 2012 Nov 21.

PMID:
23177925
[PubMed - indexed for MEDLINE]
Free PMC Article

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