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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1796 1
1807 2
1808 1
1809 1
1810 1
1814 1
1815 1
1821 2
1822 1
1823 5
1824 2
1825 2
1826 4
1827 2
1829 3
1830 2
1831 1
1832 3
1838 1
1840 5
1841 3
1842 7
1843 5
1844 6
1845 3
1846 9
1847 3
1848 3
1849 8
1850 2
1851 6
1852 10
1853 5
1854 4
1855 4
1856 4
1857 1
1858 1
1859 2
1860 8
1861 4
1862 7
1863 3
1864 2
1865 2
1866 4
1868 4
1869 8
1870 5
1871 5
1872 1
1873 2
1874 5
1875 12
1876 9
1877 3
1878 8
1879 6
1880 9
1881 7
1882 5
1883 5
1884 4
1885 3
1886 2
1887 7
1888 2
1889 4
1890 1
1891 6
1892 5
1893 7
1894 6
1895 2
1896 5
1897 9
1898 1
1899 4
1900 1
1901 1
1902 1
1903 3
1904 1
1905 4
1906 2
1907 2
1908 4
1909 5
1910 1
1911 6
1912 9
1913 1
1914 2
1915 7
1916 2
1917 4
1918 5
1919 3
1920 5
1921 5
1922 5
1923 4
1924 10
1925 12
1926 8
1927 16
1928 13
1929 10
1930 14
1931 14
1932 22
1933 19
1934 16
1935 12
1936 18
1937 20
1938 11
1939 21
1940 13
1941 8
1942 13
1943 10
1944 10
1945 50
1946 124
1947 159
1948 160
1949 148
1950 216
1951 262
1952 355
1953 383
1954 365
1955 355
1956 353
1957 380
1958 410
1959 396
1960 410
1961 435
1962 514
1963 792
1964 1180
1965 1005
1966 1051
1967 1276
1968 1584
1969 1597
1970 1588
1971 1643
1972 1641
1973 1664
1974 1636
1975 1637
1976 1502
1977 1483
1978 1573
1979 1518
1980 1474
1981 1536
1982 1609
1983 1725
1984 1857
1985 1915
1986 1883
1987 1938
1988 2039
1989 2365
1990 2487
1991 2493
1992 2654
1993 2665
1994 3015
1995 2902
1996 3055
1997 3095
1998 3299
1999 3514
2000 3894
2001 4495
2002 4829
2003 4884
2004 5478
2005 5998
2006 6458
2007 6779
2008 7244
2009 7803
2010 8196
2011 9000
2012 9367
2013 10191
2014 10326
2015 10610
2016 10907
2017 11218
2018 11809
2019 12847
2020 14343
2021 15245
2022 15644
2023 15523
2024 5855

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280,351 results

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Page 1
Haemochromatosis.
Brissot P, Pietrangelo A, Adams PC, de Graaff B, McLaren CE, Loréal O. Brissot P, et al. Nat Rev Dis Primers. 2018 Apr 5;4:18016. doi: 10.1038/nrdp.2018.16. Nat Rev Dis Primers. 2018. PMID: 29620054 Free PMC article. Review.
Haemochromatosis is defined as systemic iron overload of genetic origin, caused by a reduction in the concentration of the iron regulatory hormone hepcidin, or a reduction in hepcidin-ferroportin binding. ...Mutations in SLC40A1 (also known as FPN1; encoding …
Haemochromatosis is defined as systemic iron overload of genetic origin, caused by a reduction in the concentration of the …
Iron metabolism and atherosclerosis.
Guo Q, Qian C, Qian ZM. Guo Q, et al. Trends Endocrinol Metab. 2023 Jul;34(7):404-413. doi: 10.1016/j.tem.2023.04.003. Epub 2023 May 18. Trends Endocrinol Metab. 2023. PMID: 37210298 Review.
Here, we focus on the up-to-date advances in studies on role of iron in atherosclerosis and discuss possible reasons why patients with hereditary hemochromatosis (HH) do not show any increased incidence of atherosclerosis. ...We argue that atherosclerosis is not obs …
Here, we focus on the up-to-date advances in studies on role of iron in atherosclerosis and discuss possible reasons why patients wit …
Hemochromatosis: pathophysiology, evaluation, and management of hepatic iron overload with a focus on MRI.
Golfeyz S, Lewis S, Weisberg IS. Golfeyz S, et al. Expert Rev Gastroenterol Hepatol. 2018 Aug;12(8):767-778. doi: 10.1080/17474124.2018.1496016. Epub 2018 Jul 19. Expert Rev Gastroenterol Hepatol. 2018. PMID: 29966105 Review.
Mutations in the HFE gene lead to excess iron absorption. Excess iron in the form of non-transferrin-bound iron (NTBI) causes injury and is readily uptaken by cardiomyocytes, pancreatic islet cells, and hepatocytes. ...If caught and treated early, HH disease …
Mutations in the HFE gene lead to excess iron absorption. Excess iron in the form of non-transferrin-bound iron (NTBI) …
Hereditary hemochromatosis.
Hash RB. Hash RB. J Am Board Fam Pract. 2001 Jul-Aug;14(4):266-73. J Am Board Fam Pract. 2001. PMID: 11458969 Free article. Review.
METHODS: A MEDLINE search was performed using multiple key words related to hemochromatosis and iron metabolism. RESULTS: Most cases of hereditary hemochromatosis are caused by a single mutation to the HFE gene, resulting in unregulated dietary iron up …
METHODS: A MEDLINE search was performed using multiple key words related to hemochromatosis and iron metabolism. RESULTS: Most …
Hemochromatosis: Evaluation of the dietary iron model and regulation of hepcidin.
Rishi G, Secondes ES, Nathan Subramaniam V. Rishi G, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2550-2556. doi: 10.1016/j.bbadis.2018.05.005. Epub 2018 May 9. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29752985 Free article.
Analysis of transgenic mice with deletions or perturbations in genes known to be involved in systemic or local regulation of iron metabolism has been particularly informative. The effect of these genes on iron accumulation and hepcidin regulation is traditionally co …
Analysis of transgenic mice with deletions or perturbations in genes known to be involved in systemic or local regulation of iron met …
Iron Through the Prism of Haematology.
Porter JB. Porter JB. Br J Haematol. 2020 Nov;191(4):587-592. doi: 10.1111/bjh.17164. Br J Haematol. 2020. PMID: 33190267 Free article. Review.
Diagnostically, this began with the identification of serum ferritin as a marker of iron overload and continued later with the application of MRI-based imaging techniques for iron and its distribution. ...During this time, our scientific understanding of iron …
Diagnostically, this began with the identification of serum ferritin as a marker of iron overload and continued later with the applic …
Hepatic iron in hemochromatosis.
Adams PC. Adams PC. Dig Dis Sci. 1990 Jun;35(6):690-2. doi: 10.1007/BF01540168. Dig Dis Sci. 1990. PMID: 2344801
Ninety-two families with familial hemochromatosis were reviewed and analyzed in regard to hepatic iron and the value of the hepatic iron index (hepatic iron/age). Hepatic iron was measured in 29 hemochromatosis homozygotes, in 10 hemoc …
Ninety-two families with familial hemochromatosis were reviewed and analyzed in regard to hepatic iron and the value of the he …
[Diagnosis and treatment of iron overload].
Ruivard M, Lobbes H. Ruivard M, et al. Rev Med Interne. 2023 Dec;44(12):656-661. doi: 10.1016/j.revmed.2023.07.002. Epub 2023 Jul 26. Rev Med Interne. 2023. PMID: 37507250 Review. French.
Bloodlettings are often poorly tolerated without clear benefit. Type 1 genetic hemochromatosis (homozygous C282Y mutation on the HFE gene) leads to iron accumulation through an increase of dietary iron absorption due to hypohepcidinemia. More than 95% of h …
Bloodlettings are often poorly tolerated without clear benefit. Type 1 genetic hemochromatosis (homozygous C282Y mutation on the HFE …
Shaping the bone through iron and iron-related proteins.
Ledesma-Colunga MG, Weidner H, Vujic Spasic M, Hofbauer LC, Baschant U, Rauner M. Ledesma-Colunga MG, et al. Semin Hematol. 2021 Jul;58(3):188-200. doi: 10.1053/j.seminhematol.2021.06.002. Epub 2021 Jun 27. Semin Hematol. 2021. PMID: 34389111 Free article. Review.
Recent studies have shown that not only iron itself, but also iron-regulatory proteins that are mutated in hereditary hemochromatosis can control bone mass. This review will summarize the current knowledge on the effects of iron on bone homeostasis and …
Recent studies have shown that not only iron itself, but also iron-regulatory proteins that are mutated in hereditary hemoc …
Neonatal hemochromatosis.
Knisely AS, Mieli-Vergani G, Whitington PF. Knisely AS, et al. Gastroenterol Clin North Am. 2003 Sep;32(3):877-89, vi-vii. doi: 10.1016/s0889-8553(03)00050-5. Gastroenterol Clin North Am. 2003. PMID: 14562579 Review.
Neonatal hemochromatosis is a rare gestational condition in which iron accumulates in the fetal tissues in a distribution like that seen in hereditary hemochromatosis. ...
Neonatal hemochromatosis is a rare gestational condition in which iron accumulates in the fetal tissues in a distribution like …
280,351 results
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