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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 1
1950 2
1951 4
1952 2
1953 1
1954 2
1955 5
1956 2
1957 3
1959 2
1960 4
1961 2
1962 3
1963 4
1964 6
1965 1
1966 1
1967 4
1968 4
1969 27
1970 10
1971 16
1972 28
1973 41
1974 72
1975 72
1976 83
1977 109
1978 147
1979 119
1980 127
1981 103
1982 130
1983 157
1984 152
1985 129
1986 148
1987 137
1988 158
1989 194
1990 209
1991 181
1992 219
1993 187
1994 202
1995 206
1996 205
1997 193
1998 217
1999 187
2000 225
2001 216
2002 213
2003 268
2004 275
2005 301
2006 350
2007 374
2008 436
2009 460
2010 514
2011 500
2012 529
2013 551
2014 565
2015 587
2016 625
2017 641
2018 507
2019 523
2020 582
2021 575
2022 564
2023 567
2024 192

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14,085 results

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Page 1
Minocycline and Doxycycline: More Than Antibiotics.
Singh S, Khanna D, Kalra S. Singh S, et al. Curr Mol Pharmacol. 2021;14(6):1046-1065. doi: 10.2174/1874467214666210210122628. Curr Mol Pharmacol. 2021. PMID: 33568043 Review.
Minocycline and doxycycline both are second-generation tetracycline antibiotics with similar chemical structures and comparable antibacterial spectrum. ...Minocycline showed promising results in experimental neurology, which was due to its highly lipophilic nature. …
Minocycline and doxycycline both are second-generation tetracycline antibiotics with similar chemical structures and comparable antib …
Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial.
Hellmann-Regen J, Clemens V, Grözinger M, Kornhuber J, Reif A, Prvulovic D, Goya-Maldonado R, Wiltfang J, Gruber O, Schüle C, Padberg F, Ising M, Uhr M, Friede T, Huber C, Manook A, Baghai TC, Rupprecht R, Heuser I. Hellmann-Regen J, et al. JAMA Netw Open. 2022 Sep 1;5(9):e2230367. doi: 10.1001/jamanetworkopen.2022.30367. JAMA Netw Open. 2022. PMID: 36103181 Free PMC article. Clinical Trial.
Minocycline treatment also exhibited no statistically significant effect on secondary outcomes. CONCLUSIONS AND RELEVANCE: In this large randomized clinical trial with minocycline at a dose of 200 mg/d added to antidepressant treatment as usual for 6 weeks, minoc …
Minocycline treatment also exhibited no statistically significant effect on secondary outcomes. CONCLUSIONS AND RELEVANCE: In this la …
Minocycline.
Jonas M, Cunha BA. Jonas M, et al. Ther Drug Monit. 1982;4(2):137-45. Ther Drug Monit. 1982. PMID: 7048646 Review.
Minocycline, a second generation tetracycline derivative, was first introduced in 1967. The following review considers the physiochemical and pharmacokinetic properties, antimicrobial activity, clinical uses, and adverse effects of minocycline. Excellent tissue and …
Minocycline, a second generation tetracycline derivative, was first introduced in 1967. The following review considers the physiochem …
Tetracycline antibiotics: Potential anticancer drugs.
Li J, Qin Y, Zhao C, Zhang Z, Zhou Z. Li J, et al. Eur J Pharmacol. 2023 Oct 5;956:175949. doi: 10.1016/j.ejphar.2023.175949. Epub 2023 Aug 2. Eur J Pharmacol. 2023. PMID: 37541377 Review.
In recent years, research on tetracycline antibiotics has gradually shifted from their antibacterial effects to anticancer effects. Doxycycline, minocycline, and tigecycline as the US Food and Drug Administration (FDA) approved tetracycline antibiotics have been the main s …
In recent years, research on tetracycline antibiotics has gradually shifted from their antibacterial effects to anticancer effects. Doxycycl …
Minocycline.
Allen JC. Allen JC. Ann Intern Med. 1976 Oct;85(4):482-7. doi: 10.7326/0003-4819-85-4-482. Ann Intern Med. 1976. PMID: 788583 Review.
Minocycline has proved to have a wider spectrum of activity against both aerobic and anaerobic bacteria and has enhanced tissue penetration when compared with its tetracycline congeners. ...Though data on the frequency and severity of these symptoms are in some conflict, …
Minocycline has proved to have a wider spectrum of activity against both aerobic and anaerobic bacteria and has enhanced tissue penet …
Tigecycline.
Frampton JE, Curran MP. Frampton JE, et al. Drugs. 2005;65(18):2623-35; discussion 2636-7. doi: 10.2165/00003495-200565180-00008. Drugs. 2005. PMID: 16392879 Review.
Efficacy and tolerability of minocycline for depression: A systematic review and meta-analysis of clinical trials.
Rosenblat JD, McIntyre RS. Rosenblat JD, et al. J Affect Disord. 2018 Feb;227:219-225. doi: 10.1016/j.jad.2017.10.042. Epub 2017 Oct 28. J Affect Disord. 2018. PMID: 29102836 Review.
BACKGROUND: Minocycline has been identified as a potential novel treatment for depression. The objective of the current review is to determine the overall antidepressant efficacy and tolerability of minocycline. METHODS: Completed and ongoing clinical trials of m …
BACKGROUND: Minocycline has been identified as a potential novel treatment for depression. The objective of the current review is to …
Tigecycline.
Pankey GA. Pankey GA. J Antimicrob Chemother. 2005 Sep;56(3):470-80. doi: 10.1093/jac/dki248. Epub 2005 Jul 22. J Antimicrob Chemother. 2005. PMID: 16040625 Review.
Tigecycline, the first in a new class of antimicrobials, the glycylcyclines, is an analogue of minocycline with additional properties that negate most mechanisms mediating resistance to the tetracyclines. ...
Tigecycline, the first in a new class of antimicrobials, the glycylcyclines, is an analogue of minocycline with additional properties …
Re-defining tigecycline therapy.
De Rosa FG, Corcione S, Di Perri G, Scaglione F. De Rosa FG, et al. New Microbiol. 2015 Apr;38(2):121-36. Epub 2015 Apr 21. New Microbiol. 2015. PMID: 25915055 Free article. Review.
Minocycline and neurodegenerative diseases.
Kim HS, Suh YH. Kim HS, et al. Behav Brain Res. 2009 Jan 23;196(2):168-79. doi: 10.1016/j.bbr.2008.09.040. Epub 2008 Oct 11. Behav Brain Res. 2009. PMID: 18977395 Review.
Minocycline has been focused as a neuroprotective agent over neurodegenerative disease since it has been first reported that minocycline has neuroprotective effects in animal models of ischemic injury [Yrjanheikki J, Keinanen R, Pellikka M, Hokfelt T, Koisinaho J. . …
Minocycline has been focused as a neuroprotective agent over neurodegenerative disease since it has been first reported that minoc …
14,085 results
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