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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1868 1
1886 1
1896 1
1907 1
1914 1
1924 1
1925 1
1928 1
1937 1
1940 3
1941 1
1942 1
1944 2
1945 155
1946 496
1947 613
1948 798
1949 686
1950 1050
1951 1104
1952 752
1953 920
1954 1013
1955 1043
1956 946
1957 1168
1958 1187
1959 1088
1960 1132
1961 1233
1962 1448
1963 2293
1964 3464
1965 3191
1966 3805
1967 5007
1968 5946
1969 6747
1970 6880
1971 7644
1972 7918
1973 8356
1974 8499
1975 8485
1976 7960
1977 8040
1978 8324
1979 8910
1980 9475
1981 9673
1982 10469
1983 11280
1984 12168
1985 12837
1986 12968
1987 13268
1988 13762
1989 15129
1990 15261
1991 15766
1992 15325
1993 15467
1994 15081
1995 15016
1996 15049
1997 15087
1998 15054
1999 14980
2000 15748
2001 15975
2002 16203
2003 16929
2004 17050
2005 18737
2006 19534
2007 19987
2008 20832
2009 21888
2010 22631
2011 23587
2012 24552
2013 25587
2014 26544
2015 27009
2016 26397
2017 26354
2018 26538
2019 26847
2020 29049
2021 28660
2022 25616
2023 23260
2024 7505

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888,277 results

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Page 1
Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.
Echt DS, Liebson PR, Mitchell LB, Peters RW, Obias-Manno D, Barker AH, Arensberg D, Baker A, Friedman L, Greene HL, et al. Echt DS, et al. N Engl J Med. 1991 Mar 21;324(12):781-8. doi: 10.1056/NEJM199103213241201. N Engl J Med. 1991. PMID: 1900101 Free article. Clinical Trial.
The use of encainide and flecainide was discontinued because of excess mortality. ...Almost all cardiac deaths not due to arrhythmia were attributed to acute myocardial infarction with shock (11 patients receiving drug and 3 receiving placebo) or to chronic congesti …
The use of encainide and flecainide was discontinued because of excess mortality. ...Almost all cardiac deaths not due to arrhythmia …
Encainide.
Antonaccio MJ, Gomoll AW, Byrne JE. Antonaccio MJ, et al. Cardiovasc Drugs Ther. 1989 Oct;3(5):691-710. doi: 10.1007/BF01857621. Cardiovasc Drugs Ther. 1989. PMID: 2518680 Review.
QT interval increases only by the concomitant increase in the QRS interval. Encainide is metabolized to O-demethyl encainide (ODE) and 3-methoxy-ODE (MODE), both of which are also antiarrhythmics with similar pharmacology to encainide. ...Consequently, enc …
QT interval increases only by the concomitant increase in the QRS interval. Encainide is metabolized to O-demethyl encainide ( …
Pulmonary Hypertension and Heart Failure: A Dangerous Liaison.
Guazzi M. Guazzi M. Heart Fail Clin. 2018 Jul;14(3):297-309. doi: 10.1016/j.hfc.2018.02.006. Heart Fail Clin. 2018. PMID: 29966628 Review.
Pulmonary hypertension (PH) is a common hemodynamic evolution of heart failure (HF) with preserved or reduced ejection fraction, responsible for congestion, symptoms worsening, exercise limitation, and negative outcome. In HF of any origin, PH develops in res …
Pulmonary hypertension (PH) is a common hemodynamic evolution of heart failure (HF) with preserved or reduced ejection …
Impact of Interatrial Shunts on Invasive Hemodynamics and Exercise Tolerance in Patients With Heart Failure.
Griffin JM, Borlaug BA, Komtebedde J, Litwin SE, Shah SJ, Kaye DM, Hoendermis E, Hasenfuß G, Gustafsson F, Wolsk E, Uriel N, Burkhoff D. Griffin JM, et al. J Am Heart Assoc. 2020 Sep;9(17):e016760. doi: 10.1161/JAHA.120.016760. Epub 2020 Aug 15. J Am Heart Assoc. 2020. PMID: 32809903 Free PMC article. Review.
Approximately 50% of patients with heart failure have preserved ejection fraction. Although a wide variety of conditions cause or contribute to heart failure with preserved ejection fraction, elevated left ventricular filling pressures, particularly du …
Approximately 50% of patients with heart failure have preserved ejection fraction. Although a wide variety of conditions cause …
Flecainide and encainide.
Furlanello F, Vergara G, Bettini R, Mosna G, Gramegna L, Disertori M. Furlanello F, et al. Eur Heart J. 1987 Mar;8 Suppl A:33-40. doi: 10.1093/eurheartj/8.suppl_a.33. Eur Heart J. 1987. PMID: 3107989 Review.
Flecainide and encainide (class IC) are presently under clinical evaluation in Italy. ...Encainide shows peculiar pharmacokinetics due to hepatic oxidating metabolisation and to production of metabolites; among these the O-demethylencainide and the 3-methoxy-O-demet …
Flecainide and encainide (class IC) are presently under clinical evaluation in Italy. ...Encainide shows peculiar pharmacokine …
Cardiac dynamics.
Parmley WW, Tyberg JV, Glantz SA. Parmley WW, et al. Annu Rev Physiol. 1977;39:277-99. doi: 10.1146/annurev.ph.39.030177.001425. Annu Rev Physiol. 1977. PMID: 322599 Review.
The studies reported here were selected because of renewed interest in these areas, particularly as they relate to the evaluation and management of patients with coronary artery disease and heart failure. The first section emphasized a new conceptual approach to cha …
The studies reported here were selected because of renewed interest in these areas, particularly as they relate to the evaluation and manage …
Preterm birth and cardiac function in adulthood.
Greer C, Troughton RW, Adamson PD, Harris SL. Greer C, et al. Heart. 2022 Feb;108(3):172-177. doi: 10.1136/heartjnl-2020-318241. Epub 2021 May 20. Heart. 2022. PMID: 34016695 Review.
Accordingly, this population should be recognised as having a higher risk of heart failure as they age. In this review, we present current evidence for increased rates of heart failure and evidence of alterations in cardiac structure and function in th …
Accordingly, this population should be recognised as having a higher risk of heart failure as they age. In this review, we pre …
Pathophysiology of chronic heart failure.
Seixas-Cambão M, Leite-Moreira AF. Seixas-Cambão M, et al. Rev Port Cardiol. 2009 Apr;28(4):439-71. Rev Port Cardiol. 2009. PMID: 19634500 Review. English, Portuguese.
Heart failure is a medical condition characterized by reduced cardiac output (CO) and increased venous pressure, associated with underlying molecular changes and subsequent damage to and death of cardiac muscle cells. ...Neurohumoral mechanisms are classified accord …
Heart failure is a medical condition characterized by reduced cardiac output (CO) and increased venous pressure, associated wi …
Association between heart rate variability and haemodynamic response to exercise in chronic heart failure.
Koshy A, Okwose NC, Nunan D, Toms A, Brodie DA, Doherty P, Seferovic P, Ristic A, Velicki L, Filipovic N, Popovic D, Skinner J, Bailey K, MacGowan GA, Jakovljevic DG. Koshy A, et al. Scand Cardiovasc J. 2019 Apr;53(2):77-82. doi: 10.1080/14017431.2019.1590629. Epub 2019 Apr 8. Scand Cardiovasc J. 2019. PMID: 30835563 Free article.
OBJECTIVES: Heart rate variability (HRV) and haemodynamic response to exercise (i.e. peak cardiac power output) are strong predictors of mortality in heart failure. ...DESIGN: In a prospective observational study of 33 patients (age 54 16 years) with …
OBJECTIVES: Heart rate variability (HRV) and haemodynamic response to exercise (i.e. peak cardiac power output) are strong pre …
Hemodynamic Instability in Heart Failure Intensifies Age-Dependent Cognitive Decline.
de la Torre JC. de la Torre JC. J Alzheimers Dis. 2020;76(1):63-84. doi: 10.3233/JAD-200296. J Alzheimers Dis. 2020. PMID: 32444552 Review.
This review attempts to examine two key elements in the evolution of cognitive impairment in the elderly who develop heart failure. First, major left side heart parts can structurally and functionally deteriorate from aging wear and tear to provoke hemodyn …
This review attempts to examine two key elements in the evolution of cognitive impairment in the elderly who develop heart failure …
888,277 results
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