Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation.
Wei TT, Chandy M, Nishiga M, Zhang A, Kumar KK, Thomas D, Manhas A, Rhee S, Justesen JM, Chen IY, Wo HT, Khanamiri S, Yang JY, Seidl FJ, Burns NZ, Liu C, Sayed N, Shie JJ, Yeh CF, Yang KC, Lau E, Lynch KL, Rivas M, Kobilka BK, Wu JC.
Wei TT, et al.
Cell. 2022 May 12;185(10):1676-1693.e23. doi: 10.1016/j.cell.2022.04.005. Epub 2022 Apr 29.
Cell. 2022.
PMID: 35489334
Free PMC article.
Epidemiological studies reveal that marijuana increases the risk of cardiovascular disease (CVD); however, little is known about the mechanism. delta(9)-tetrahydrocannabinol (delta(9)-THC), the psychoactive component of marijuana, binds to cannabinoid receptor 1 (CB1/CNR1) in the …
Epidemiological studies reveal that marijuana increases the risk of cardiovascular disease (CVD); however, little is known about the mechani …