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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1942 2
1943 4
1944 11
1945 634
1946 2219
1947 2541
1948 2837
1949 2704
1950 4360
1951 4584
1952 4772
1953 5001
1954 4255
1955 4021
1956 3902
1957 3890
1958 3519
1959 3180
1960 3078
1961 3325
1962 3796
1963 5809
1964 7076
1965 5947
1966 5517
1967 6549
1968 7112
1969 7792
1970 7870
1971 8369
1972 8213
1973 8879
1974 9147
1975 8477
1976 8176
1977 8225
1978 8060
1979 8782
1980 8529
1981 8825
1982 9699
1983 10072
1984 10765
1985 11264
1986 11014
1987 10954
1988 11233
1989 12172
1990 12147
1991 12133
1992 12109
1993 12311
1994 12325
1995 13311
1996 13709
1997 14090
1998 15010
1999 15179
2000 15996
2001 16892
2002 17321
2003 18020
2004 18870
2005 20294
2006 21674
2007 22692
2008 23917
2009 24892
2010 26193
2011 28542
2012 30486
2013 32253
2014 33488
2015 34325
2016 35420
2017 36430
2018 38519
2019 41768
2020 45965
2021 47563
2022 48252
2023 45009
2024 15819

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1,091,714 results

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Page 1
Lyme disease: diagnosis and treatment.
Schoen RT. Schoen RT. Curr Opin Rheumatol. 2020 May;32(3):247-254. doi: 10.1097/BOR.0000000000000698. Curr Opin Rheumatol. 2020. PMID: 32141956 Review.
This review examines the emergence, clinical features and management of early Lyme disease and Lyme arthritis. RECENT FINDINGS: There has been continuing progress in characterizing the clinical manifestations, diagnostic testing and treatment of Lyme …
This review examines the emergence, clinical features and management of early Lyme disease and Lyme arthritis. RECENT F …
Challenges in the Diagnosis and Treatment of Lyme Disease.
Schoen RT. Schoen RT. Curr Rheumatol Rep. 2020 Jan 7;22(1):3. doi: 10.1007/s11926-019-0857-2. Curr Rheumatol Rep. 2020. PMID: 31912251 Review.
The purpose of this review is to examine advances in the diagnosis and treatment of Lyme disease, as well as ongoing management challenges. RECENT FINDINGS: It is useful to recognize that Lyme disease occurs in stages, with early- and late-stage dis …
The purpose of this review is to examine advances in the diagnosis and treatment of Lyme disease, as well as ongoing managemen …
Chronic Lyme disease.
Lantos PM. Lantos PM. Infect Dis Clin North Am. 2015 Jun;29(2):325-40. doi: 10.1016/j.idc.2015.02.006. Infect Dis Clin North Am. 2015. PMID: 25999227 Free PMC article. Review.
Chronic Lyme disease is a poorly defined diagnosis that is usually given to patients with prolonged, unexplained symptoms or with alternative medical diagnoses. Data do not support the proposition that chronic, treatment-refractory infection with Borrelia burgdorfer …
Chronic Lyme disease is a poorly defined diagnosis that is usually given to patients with prolonged, unexplained symptoms or w …
Antibiotics and Antibiotic Resistance- Flipsides of the Same Coin.
Bhardwaj S, Mehra P, Dhanjal DS, Sharma P, Sharma V, Singh R, Nepovimova E, Chopra C, Kuča K. Bhardwaj S, et al. Curr Pharm Des. 2022;28(28):2312-2329. doi: 10.2174/1381612828666220608120238. Curr Pharm Des. 2022. PMID: 35676839 Review.
One of the major global health care crises in the 21st century is antibiotic resistance. Almost all clinically used antibiotics have resistance emerging to them. ...It has become peremptory to develop treatment options as an alternative to antibiotic therapy …
One of the major global health care crises in the 21st century is antibiotic resistance. Almost all clinically used antibiotics …
Antibiotic use: present and future.
Zinner SH. Zinner SH. New Microbiol. 2007 Jul;30(3):321-5. New Microbiol. 2007. PMID: 17802919 Free article. Review.
However, the future could look dim, as there are relatively few new agents on the horizon. A bold new look for antibacterial targets is needed. ...New approaches to antimicrobial chemotherapy are needed if we are to survive the increasing rates of antibiotic resista …
However, the future could look dim, as there are relatively few new agents on the horizon. A bold new look for antibacterial targets …
Antibiotics and Bacterial Resistance-A Short Story of an Endless Arms Race.
Baran A, Kwiatkowska A, Potocki L. Baran A, et al. Int J Mol Sci. 2023 Mar 17;24(6):5777. doi: 10.3390/ijms24065777. Int J Mol Sci. 2023. PMID: 36982857 Free PMC article. Review.
However, the widespread availability of antibiotics, accompanied by their overprescription, acts as a double-edged sword, since the overuse and/or misuse of antibiotics leads to a growing number of multidrug-resistant microbes. ...Amongst the most common bacterial r …
However, the widespread availability of antibiotics, accompanied by their overprescription, acts as a double-edged sword, since the o …
Antibiotic prophylaxis in orthopedics-traumatology.
Gaudias J. Gaudias J. Orthop Traumatol Surg Res. 2021 Feb;107(1S):102751. doi: 10.1016/j.otsr.2020.102751. Epub 2020 Dec 11. Orthop Traumatol Surg Res. 2021. PMID: 33316449 Free article. Review.
When all rules of hygiene have been scrupulously applied, antibiotic prophylaxis (ABP) is the one remaining means of further reducing surgical site infection risk. ...It is easy enough to conceive of ABP in terms of the tissue pharmacokinetics of the antibiotic(s …
When all rules of hygiene have been scrupulously applied, antibiotic prophylaxis (ABP) is the one remaining means of further reducing …
Lyme Arthritis.
Arvikar SL, Steere AC. Arvikar SL, et al. Infect Dis Clin North Am. 2022 Sep;36(3):563-577. doi: 10.1016/j.idc.2022.03.006. Infect Dis Clin North Am. 2022. PMID: 36116835 Free PMC article. Review.
Arthritis is the most common late manifestation of Borrelia burgdorferi infection in the United States, usually beginning months after the tick bite. In most patients with Lyme arthritis (LA) today, arthritis is the presenting manifestation of the disease. ...Serolo …
Arthritis is the most common late manifestation of Borrelia burgdorferi infection in the United States, usually beginning months after the t …
What is an "ideal" antibiotic? Discovery challenges and path forward.
Singh SB, Young K, Silver LL. Singh SB, et al. Biochem Pharmacol. 2017 Jun 1;133:63-73. doi: 10.1016/j.bcp.2017.01.003. Epub 2017 Jan 10. Biochem Pharmacol. 2017. PMID: 28087253 Review.
Sadly, no such antibiotics exist. What exist are many effective Gram-positive antibacterial agents as well as broad-spectrum agents that provide treatment of certain Gram-negative bacteria but not holistic treatment of all bacteria. However effectiveness of a …
Sadly, no such antibiotics exist. What exist are many effective Gram-positive antibacterial agents as well as broad-spectrum …
Link Between Antibiotic Persistence and Antibiotic Resistance in Bacterial Pathogens.
Eisenreich W, Rudel T, Heesemann J, Goebel W. Eisenreich W, et al. Front Cell Infect Microbiol. 2022 Jul 19;12:900848. doi: 10.3389/fcimb.2022.900848. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35928205 Free PMC article. Review.
Both, antibiotic persistence and antibiotic resistance characterize phenotypes of survival in which a bacterial cell becomes insensitive to one (or even) more antibiotic(s). ...The molecular basics of antibiotic resistance are in principle well …
Both, antibiotic persistence and antibiotic resistance characterize phenotypes of survival in which a bacterial cell becomes i …
1,091,714 results
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