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Results: 1 to 20 of 37

1.

Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa.

Tam BM, Noorwez SM, Kaushal S, Kono M, Moritz OL.

J Neurosci. 2014 Oct 1;34(40):13336-48. doi: 10.1523/JNEUROSCI.1655-14.2014.

PMID:
25274813
[PubMed - indexed for MEDLINE]
2.

The Gos28 SNARE protein mediates intra-Golgi transport of rhodopsin and is required for photoreceptor survival.

Rosenbaum EE, Vasiljevic E, Cleland SC, Flores C, Colley NJ.

J Biol Chem. 2014 Nov 21;289(47):32392-409. doi: 10.1074/jbc.M114.585166. Epub 2014 Sep 26.

PMID:
25261468
[PubMed - indexed for MEDLINE]
3.

Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of the Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis.

Onish C, Mori-Kimachi S, Hirade T, Abe M, Taketani T, Suzumiya J, Sugimoto T, Yamaguchi S, Kapur R, Fukuda S.

J Biol Chem. 2014 Nov 7;289(45):31053-65. doi: 10.1074/jbc.M114.568287. Epub 2014 Sep 18.

PMID:
25237195
[PubMed - indexed for MEDLINE]
4.

An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration.

Kutys ML, Yamada KM.

Nat Cell Biol. 2014 Sep;16(9):909-17. doi: 10.1038/ncb3026. Epub 2014 Aug 24.

PMID:
25150978
[PubMed - indexed for MEDLINE]
5.

Role of Rho small GTPases in meniscus cells.

Kanazawa T, Furumatsu T, Matsumoto-Ogawa E, Maehara A, Ozaki T.

J Orthop Res. 2014 Nov;32(11):1479-86. doi: 10.1002/jor.22703. Epub 2014 Aug 11.

PMID:
25130858
[PubMed - indexed for MEDLINE]
6.

Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation.

Oleinik NV, Helke KL, Kistner-Griffin E, Krupenko NI, Krupenko SA.

J Biol Chem. 2014 Sep 19;289(38):26383-94. doi: 10.1074/jbc.M114.569657. Epub 2014 Aug 1.

PMID:
25086046
[PubMed - indexed for MEDLINE]
7.

Rho GTPases modulate malignant transformation of tumor cells.

Orgaz JL, Herraiz C, Sanz-Moreno V.

Small GTPases. 2014;5:e29019. doi: 10.4161/sgtp.29019. Epub 2014 May 8. Review.

PMID:
25036871
[PubMed - indexed for MEDLINE]
8.

Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions.

Julian L, Olson MF.

Small GTPases. 2014;5:e29846. doi: 10.4161/sgtp.29846. Epub 2014 Jul 10. Review.

PMID:
25010901
[PubMed - indexed for MEDLINE]
9.

Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells.

Chircop M.

Small GTPases. 2014;5. pii: e29770. doi: 10.4161/sgtp.29770. Epub 2014 Jul 2. Review.

PMID:
24988197
[PubMed - indexed for MEDLINE]
10.

Contribution of glutamic acid in the conserved E/DRY triad to the functional properties of rhodopsin.

Sato K, Yamashita T, Shichida Y.

Biochemistry. 2014 Jul 15;53(27):4420-5. doi: 10.1021/bi5003772. Epub 2014 Jul 1.

PMID:
24960425
[PubMed - indexed for MEDLINE]
11.

A novel interaction between the SH2 domain of signaling adaptor protein Nck-1 and the upstream regulator of the Rho family GTPase Rac1 engulfment and cell motility 1 (ELMO1) promotes Rac1 activation and cell motility.

Zhang G, Chen X, Qiu F, Zhu F, Lei W, Nie J.

J Biol Chem. 2014 Aug 15;289(33):23112-22. doi: 10.1074/jbc.M114.549550. Epub 2014 Jun 13.

PMID:
24928514
[PubMed - indexed for MEDLINE]
12.

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome.

Xu H, Yang J, Gao W, Li L, Li P, Zhang L, Gong YN, Peng X, Xi JJ, Chen S, Wang F, Shao F.

Nature. 2014 Sep 11;513(7517):237-41. doi: 10.1038/nature13449. Epub 2014 Jun 11.

PMID:
24919149
[PubMed - indexed for MEDLINE]
13.

Up-regulation of Rhoa/Rho kinase pathway by translationally controlled tumor protein in vascular smooth muscle cells.

Maeng J, Sheverdin V, Shin H, Ha I, Bae SS, Yang-Yen HF, Lee K.

Int J Mol Sci. 2014 Jun 10;15(6):10365-76. doi: 10.3390/ijms150610365.

PMID:
24918292
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo AA, Rodrigues M, Zaidi MR, Ksander BR, Merlino G, Sodhi A, Chen Q, Gutkind JS.

Cancer Cell. 2014 Jun 16;25(6):831-45. doi: 10.1016/j.ccr.2014.04.016. Epub 2014 May 29.

PMID:
24882515
[PubMed - indexed for MEDLINE]
15.

The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa.

Parfitt DA, Aguila M, McCulley CH, Bevilacqua D, Mendes HF, Athanasiou D, Novoselov SS, Kanuga N, Munro PM, Coffey PJ, Kalmar B, Greensmith L, Cheetham ME.

Cell Death Dis. 2014 May 22;5:e1236. doi: 10.1038/cddis.2014.214.

PMID:
24853414
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Rho GTPases, oxidation, and cell redox control.

Hobbs GA, Zhou B, Cox AD, Campbell SL.

Small GTPases. 2014;5:e28579. doi: 10.4161/sgtp.28579. Epub 2014 May 8. Review.

PMID:
24809833
[PubMed - indexed for MEDLINE]
17.

The malignancy of metastatic ovarian cancer cells is increased on soft matrices through a mechanosensitive Rho-ROCK pathway.

McGrail DJ, Kieu QM, Dawson MR.

J Cell Sci. 2014 Jun 15;127(Pt 12):2621-6. doi: 10.1242/jcs.144378. Epub 2014 Apr 16.

PMID:
24741068
[PubMed - indexed for MEDLINE]
Free Article
18.

Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.

Tsou PS, Haak AJ, Khanna D, Neubig RR.

Am J Physiol Cell Physiol. 2014 Jul 1;307(1):C2-13. doi: 10.1152/ajpcell.00060.2014. Epub 2014 Apr 16. Review.

PMID:
24740541
[PubMed - indexed for MEDLINE]
19.

Intramolecular interactions that induce helical rearrangement upon rhodopsin activation: light-induced structural changes in metarhodopsin IIa probed by cysteine S-H stretching vibrations.

Yamazaki Y, Nagata T, Terakita A, Kandori H, Shichida Y, Imamoto Y.

J Biol Chem. 2014 May 16;289(20):13792-800. doi: 10.1074/jbc.M113.527606. Epub 2014 Apr 1.

PMID:
24692562
[PubMed - indexed for MEDLINE]
20.

Increased diacylglycerol kinase ΞΆ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion.

Cai K, Mulatz K, Ard R, Nguyen T, Gee SH.

BMC Cancer. 2014 Mar 19;14:208. doi: 10.1186/1471-2407-14-208.

PMID:
24646293
[PubMed - indexed for MEDLINE]
Free PMC Article
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