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Results: 11

1.

Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest.

Nizialek EA, Peterson C, Mester JL, Downes-Kelly E, Eng C.

Hum Mol Genet. 2013 Jun 15;22(12):2451-61. doi: 10.1093/hmg/ddt097. Epub 2013 Feb 27.

PMID:
23446638
[PubMed - indexed for MEDLINE]
2.

Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas.

Wang Y, He X, Yu Q, Eng C.

Hum Mol Genet. 2013 Jun 1;22(11):2263-72. doi: 10.1093/hmg/ddt077. Epub 2013 Feb 14.

PMID:
23418309
[PubMed - indexed for MEDLINE]
3.

Transcription factor KLLN inhibits tumor growth by AR suppression, induces apoptosis by TP53/TP73 stimulation in prostate carcinomas, and correlates with cellular differentiation.

Wang Y, Radhakrishnan D, He X, Peehl DM, Eng C.

J Clin Endocrinol Metab. 2013 Mar;98(3):E586-94. doi: 10.1210/jc.2012-3490. Epub 2013 Feb 5.

PMID:
23386643
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Analysis of KLLN as a high-penetrance breast cancer predisposition gene.

Thompson ER, Gorringe KL, Choong DY, Eccles DM; kConFab, Mitchell G, Campbell IG.

Breast Cancer Res Treat. 2012 Jul;134(2):543-7. doi: 10.1007/s10549-012-2088-3. Epub 2012 May 13.

PMID:
22580995
[PubMed - indexed for MEDLINE]
5.

Incidence and clinical characteristics of thyroid cancer in prospective series of individuals with Cowden and Cowden-like syndrome characterized by germline PTEN, SDH, or KLLN alterations.

Ngeow J, Mester J, Rybicki LA, Ni Y, Milas M, Eng C.

J Clin Endocrinol Metab. 2011 Dec;96(12):E2063-71. doi: 10.1210/jc.2011-1616. Epub 2011 Sep 28.

PMID:
21956414
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma.

Bennett KL, Campbell R, Ganapathi S, Zhou M, Rini B, Ganapathi R, Neumann HP, Eng C.

Genes Chromosomes Cancer. 2011 Aug;50(8):654-61. doi: 10.1002/gcc.20887. Epub 2011 May 16.

PMID:
21584899
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

S-phase-coupled apoptosis in tumor suppression.

Cho YJ, Liang P.

Cell Mol Life Sci. 2011 Jun;68(11):1883-96. doi: 10.1007/s00018-011-0666-x. Epub 2011 Mar 25. Review.

PMID:
21437646
[PubMed - indexed for MEDLINE]
8.

KILLIN gene discovery stirs up research on Cowden syndrome cancers.

Schmidt C.

J Natl Cancer Inst. 2011 Mar 2;103(5):362-4. doi: 10.1093/jnci/djr055. Epub 2011 Feb 25. No abstract available.

PMID:
21357597
[PubMed - indexed for MEDLINE]
Free Article
9.

PTEN promoter silencing and Cowden syndrome: the role of epigenetic regulation of KILLIN.

Jelovac D, Park BH.

JAMA. 2010 Dec 22;304(24):2744-5. doi: 10.1001/jama.2010.1863. No abstract available.

PMID:
21177512
[PubMed - indexed for MEDLINE]
10.

Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome.

Bennett KL, Mester J, Eng C.

JAMA. 2010 Dec 22;304(24):2724-31. doi: 10.1001/jama.2010.1877.

PMID:
21177507
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Killin is a p53-regulated nuclear inhibitor of DNA synthesis.

Cho YJ, Liang P.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5396-401. doi: 10.1073/pnas.0705410105. Epub 2008 Apr 2.

PMID:
18385383
[PubMed - indexed for MEDLINE]
Free PMC Article

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