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Results: 1 to 20 of 132

1.
2.

Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling.

Beaufort N, Scharrer E, Kremmer E, Lux V, Ehrmann M, Huber R, Houlden H, Werring D, Haffner C, Dichgans M.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16496-501. doi: 10.1073/pnas.1418087111. Epub 2014 Nov 4.

PMID:
25369932
3.

A functional approach to examine the role of HTRA1 versus ARMS2 in AMD.

Fu Y.

Invest Ophthalmol Vis Sci. 2014 Oct 16;55(10):6524. doi: 10.1167/iovs.14-15670. No abstract available.

PMID:
25324346
4.

Overexpression of HtrA1 and exposure to mainstream cigarette smoke leads to choroidal neovascularization and subretinal deposits in aged mice.

Nakayama M, Iejima D, Akahori M, Kamei J, Goto A, Iwata T.

Invest Ophthalmol Vis Sci. 2014 Sep 9;55(10):6514-23. doi: 10.1167/iovs.14-14453.

PMID:
25205867
5.

Genomic aspects of age-related macular degeneration.

Horie-Inoue K, Inoue S.

Biochem Biophys Res Commun. 2014 Sep 19;452(2):263-75. doi: 10.1016/j.bbrc.2014.08.013. Epub 2014 Aug 8. Review.

PMID:
25111812
6.

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

Jeffries MA, Donica M, Baker LW, Stevenson ME, Annan AC, Humphrey MB, James JA, Sawalha AH.

Arthritis Rheumatol. 2014 Oct;66(10):2804-15. doi: 10.1002/art.38762.

PMID:
24980887
7.

The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis.

Hou Y, Lin H, Zhu L, Liu Z, Hu F, Shi J, Yang T, Shi X, Guo H, Tan X, Zhang L, Wang Q, Li Z, Zhao Y.

J Immunol. 2014 Jul 1;193(1):130-8. doi: 10.4049/jimmunol.1302700. Epub 2014 Jun 6.

PMID:
24907345
8.

Rare complement factor H variant associated with age-related macular degeneration in the Amish.

Hoffman JD, Cooke Bailey JN, D'Aoust L, Cade W, Ayala-Haedo J, Fuzzell D, Laux R, Adams LD, Reinhart-Mercer L, Caywood L, Whitehead-Gay P, Agarwal A, Wang G, Scott WK, Pericak-Vance MA, Haines JL.

Invest Ophthalmol Vis Sci. 2014 Jun 6;55(7):4455-60. doi: 10.1167/iovs.13-13684.

9.

Angiographic features of transgenic mice with increased expression of human serine protease HTRA1 in retinal pigment epithelium.

Kumar S, Berriochoa Z, Ambati BK, Fu Y.

Invest Ophthalmol Vis Sci. 2014 May 22;55(6):3842-50. doi: 10.1167/iovs.13-13111.

PMID:
24854852
10.

Identification of prosaposin and transgelin as potential biomarkers for gallbladder cancer using quantitative proteomics.

Sahasrabuddhe NA, Barbhuiya MA, Bhunia S, Subbannayya T, Gowda H, Advani J, Shrivastav BR, Navani S, Leal P, Roa JC, Chaerkady R, Gupta S, Chatterjee A, Pandey A, Tiwari PK.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):863-9. doi: 10.1016/j.bbrc.2014.03.017. Epub 2014 Mar 20.

PMID:
24657443
11.

Biological characterization and analysis of metastasis-related genes in cell lines derived from the primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the mandibular gingiva.

Fujinaga T, Kumamaru W, Sugiura T, Kobayashi Y, Ohyama Y, Ikari T, Onimaru M, Akimoto N, Jogo R, Mori Y.

Int J Oncol. 2014 May;44(5):1614-24. doi: 10.3892/ijo.2014.2332. Epub 2014 Mar 10.

PMID:
24627082
12.

Mutation in the HTRA1 gene in a patient with degenerated spine as a component of CARASIL syndrome.

Bayrakli F, Balaban H, Gurelik M, Hizmetli S, Topaktas S.

Turk Neurosurg. 2014;24(1):67-9. doi: 10.5137/1019-5149.JTN.6226-12.1.

13.

Two novel HTRA1 mutations in a European CARASIL patient.

Bianchi S, Di Palma C, Gallus GN, Taglia I, Poggiani A, Rosini F, Rufa A, Muresanu DF, Cerase A, Dotti MT, Federico A.

Neurology. 2014 Mar 11;82(10):898-900. doi: 10.1212/WNL.0000000000000202. Epub 2014 Feb 5. No abstract available.

PMID:
24500651
14.

Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines.

Yang J, Li Y, Chan L, Tsai YT, Wu WH, Nguyen HV, Hsu CW, Li X, Brown LM, Egli D, Sparrow JR, Tsang SH.

Hum Mol Genet. 2014 Jul 1;23(13):3445-55. doi: 10.1093/hmg/ddu053. Epub 2014 Feb 4.

PMID:
24497574
15.

Genes in the high-density lipoprotein metabolic pathway in age-related macular degeneration and polypoidal choroidal vasculopathy.

Liu K, Chen LJ, Lai TY, Tam PO, Ho M, Chiang SW, Liu DT, Young AL, Yang Z, Pang CP.

Ophthalmology. 2014 Apr;121(4):911-6. doi: 10.1016/j.ophtha.2013.10.042. Epub 2014 Jan 3.

PMID:
24393350
16.

HtrA1 downregulation induces cisplatin resistance in lung adenocarcinoma by promoting cancer stem cell-like properties.

Xu Y, Jiang Z, Zhang Z, Sun N, Zhang M, Xie J, Li T, Hou Y, Wu D.

J Cell Biochem. 2014 Jun;115(6):1112-21. doi: 10.1002/jcb.24751.

PMID:
24356998
17.

Chromosome 10q26 locus and age-related macular degeneration: a progress update.

Wang G.

Exp Eye Res. 2014 Feb;119:1-7. doi: 10.1016/j.exer.2013.11.009. Epub 2013 Nov 28. Review.

PMID:
24291204
18.

Genetic association with response to intravitreal ranibizumab for neovascular age-related macular degeneration in the Han Chinese population.

Yuan D, Yuan D, Liu X, Yuan S, Xie P, Liu Q.

Ophthalmologica. 2013;230(4):227-32. doi: 10.1159/000355068. Epub 2013 Sep 25.

PMID:
24080590
19.

Pharmacogenetic associations with vascular endothelial growth factor inhibition in participants with neovascular age-related macular degeneration in the IVAN Study.

Lotery AJ, Gibson J, Cree AJ, Downes SM, Harding SP, Rogers CA, Reeves BC, Ennis S, Chakravarthy U; Alternative Treatments to Inhibit VEGF in Patients with Age-Related Choroidal Neovascularisation (IVAN) Study Group.

Ophthalmology. 2013 Dec;120(12):2637-43. doi: 10.1016/j.ophtha.2013.07.046. Epub 2013 Sep 23.

PMID:
24070809
20.

Serine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation.

Graham JR, Chamberland A, Lin Q, Li XJ, Dai D, Zeng W, Ryan MS, Rivera-Bermúdez MA, Flannery CR, Yang Z.

PLoS One. 2013 Sep 11;8(9):e74094. doi: 10.1371/journal.pone.0074094. eCollection 2013.

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