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Year Number of Results
2019 14
2020 24
2021 12
2022 9
2023 7
2024 4

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Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung.
Schupp JC, Adams TS, Cosme C Jr, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe'er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Schupp JC, et al. Circulation. 2021 Jul 27;144(4):286-302. doi: 10.1161/CIRCULATIONAHA.120.052318. Epub 2021 May 25. Circulation. 2021. PMID: 34030460 Free PMC article.
Beyond the broad cellular categories of lymphatic, capillary, arterial, and venous ECs, we found previously indistinguishable subpopulations; among venous EC, we identified 2 previously indistinguishable populations: pulmonary-venous ECs (COL15A1(neg)) localized to the lung paren …
Beyond the broad cellular categories of lymphatic, capillary, arterial, and venous ECs, we found previously indistinguishable subpopulations …
Comprehensive characterization of the genetic landscape of familial Hirschsprung's disease.
Xiao J, Hao LW, Wang J, Yu XS, You JY, Li ZJ, Mao HD, Meng XY, Feng JX. Xiao J, et al. World J Pediatr. 2023 Jul;19(7):644-651. doi: 10.1007/s12519-023-00686-x. Epub 2023 Mar 1. World J Pediatr. 2023. PMID: 36857021 Free PMC article. Review.
The primary gene factors in the syndromic families are ret proto-oncogene (RET) and endothelin B receptor gene (EDNRB). Most families show incomplete dominance and are relevant to RET, and the RET mutation has 56% penetrance in familial HSCR. ...
The primary gene factors in the syndromic families are ret proto-oncogene (RET) and endothelin B receptor gene (EDNRB). Most families …
Role of endothelin receptor type B (EDNRB) in lung adenocarcinoma.
Wei F, Ge Y, Li W, Wang X, Chen B. Wei F, et al. Thorac Cancer. 2020 Jul;11(7):1885-1890. doi: 10.1111/1759-7714.13474. Epub 2020 May 12. Thorac Cancer. 2020. PMID: 32394530 Free PMC article.
BACKGROUND: The five-year survival rate of lung adenocarcinoma patients (LUAD) is very low,and the methods of predicting survival are a great obstacle for LUAD therapies. Endothelin receptor type B (EDNRB) gene is associated with tumorigenesis. …
BACKGROUND: The five-year survival rate of lung adenocarcinoma patients (LUAD) is very low,and the methods of predicting survival are a grea …
Knockdown of endothelin receptor B inhibits the progression of triple-negative breast cancer.
Gu X, Han S, Cui M, Xue J, Ai L, Sun L, Zhu X, Wang Y, Liu C. Gu X, et al. Ann N Y Acad Sci. 2019 Jul;1448(1):5-18. doi: 10.1111/nyas.14039. Epub 2019 Mar 22. Ann N Y Acad Sci. 2019. PMID: 30900271
EDNRB expression was particularly upregulated in triple-negative breast cancer (TNBC) cells. ...Therefore, our findings provide strong evidence for the first time that knockdown of EDNRB expression inhibits the progression of TNBC and that EDNRB can serve as …
EDNRB expression was particularly upregulated in triple-negative breast cancer (TNBC) cells. ...Therefore, our findings provide stron …
Genetic heterogeneity in GJB2, COL4A3, ATP6V1B1 and EDNRB variants detected among hearing impaired families in Morocco.
AitRaise I, Amalou G, Bousfiha A, Charoute H, Rouba H, Abdelghaffar H, Bonnet C, Petit C, Barakat A. AitRaise I, et al. Mol Biol Rep. 2022 May;49(5):3949-3954. doi: 10.1007/s11033-022-07245-z. Epub 2022 Mar 17. Mol Biol Rep. 2022. PMID: 35301649
THE RESULTS: The results of four out of the six families revealed four genetic variants in the genes GJB2, COL4A3, ATP6V1B1 and EDNRB responsible for non-syndromic and syndromic hearing loss. Multiple Bioinformatics programs and molecular modelling predicted the pathogenic …
THE RESULTS: The results of four out of the six families revealed four genetic variants in the genes GJB2, COL4A3, ATP6V1B1 and EDNRB …
Single-cell transcriptomic profiling of microvascular endothelial cell heterogeneity in congenital diaphragmatic hernia.
Robertson JO, Bazeley P, Erzurum SC, Asosingh K. Robertson JO, et al. Sci Rep. 2023 Jun 17;13(1):9851. doi: 10.1038/s41598-023-37050-y. Sci Rep. 2023. PMID: 37330615 Free PMC article.
Only the CDH mvEC cluster had a distinct inflammatory transcriptomic signature as compared to the 2HC and NC endothelial cells, e.g. greater activation and adhesion of inflammatory cells and production of reactive oxygen species. Furthermore, CDH mvECs had downregulated Ca4, Apln …
Only the CDH mvEC cluster had a distinct inflammatory transcriptomic signature as compared to the 2HC and NC endothelial cells, e.g. greater …
Associations of EDNRA and EDNRB Polymorphisms with Intracerebral Hemorrhage.
Zeng Y, Chen R, Ma M, Liu B, Xia J, Xu H, Liu Y, Du X, Hu Z, Yang Q, Zhang L. Zeng Y, et al. World Neurosurg. 2019 Sep;129:e472-e477. doi: 10.1016/j.wneu.2019.05.186. Epub 2019 May 29. World Neurosurg. 2019. PMID: 31150867
Recent studies have demonstrated increased plasma endothelin-1 level in ICH patients and relationships between EDNRA and EDNRB genetic variants and ischemic stroke. The aim of the current study was to investigate whether EDNRA and EDNRB polymorphisms are associated …
Recent studies have demonstrated increased plasma endothelin-1 level in ICH patients and relationships between EDNRA and EDNRB geneti …
The clinical and genetic research of Waardenburg syndrome type I and II in Chinese families.
Liu Q, Cheng J, Lu Y, Zhou J, Wang L, Yang C, Yang G, Yang H, Cao J, Zhang Z, Sun Y. Liu Q, et al. Int J Pediatr Otorhinolaryngol. 2020 Mar;130:109806. doi: 10.1016/j.ijporl.2019.109806. Epub 2019 Nov 29. Int J Pediatr Otorhinolaryngol. 2020. PMID: 31812001
OBJECTIVE: Waardenburg Syndrome (WS) is a neurocristopathy with an autosomal dominant mode of inheritance and highly genetic heterogeneity. To date, mutations of PAX3, SOX10, MITF, EDNRB, EDN3 and SNAI2 have been implicated in the pathogenesis of WS. ...METHODS: In this st …
OBJECTIVE: Waardenburg Syndrome (WS) is a neurocristopathy with an autosomal dominant mode of inheritance and highly genetic heterogeneity. …
Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next-generation sequencing.
Lee CY, Lo MY, Chen YM, Lin PH, Hsu CJ, Chen PL, Wu CC, Hsu JS. Lee CY, et al. Mol Genet Genomic Med. 2022 Dec;10(12):e2082. doi: 10.1002/mgg3.2082. Epub 2022 Nov 4. Mol Genet Genomic Med. 2022. PMID: 36331148 Free PMC article.
Of these variants, nine were novel and discovered in PAX3, SOX10, EDNRB, and MITF genes, including missense, nonsense, deletion, and splice site variants. ...
Of these variants, nine were novel and discovered in PAX3, SOX10, EDNRB, and MITF genes, including missense, nonsense, deletion, and …
A gene regulatory network explains RET-EDNRB epistasis in Hirschsprung disease.
Chatterjee S, Chakravarti A. Chatterjee S, et al. Hum Mol Genet. 2019 Sep 15;28(18):3137-3147. doi: 10.1093/hmg/ddz149. Hum Mol Genet. 2019. PMID: 31313802 Free PMC article.
Significantly, RET and EDNRB expression is regulated by their shared use of GATA2 and SOX10, and in turn, these TFs are controlled by EDNRB and RET in a dose-dependent manner. This study expands the ENS development GRN to include both RET and EDNRB, uncovers …
Significantly, RET and EDNRB expression is regulated by their shared use of GATA2 and SOX10, and in turn, these TFs are controlled by …
60 results