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Results: 1 to 20 of 31

Select item 232631601.

Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.

Morad SA, Messner MC, Levin JC, Abdelmageed N, Park H, Merrill AH Jr, Cabot MC.

Cancer Chemother Pharmacol. 2013 Mar;71(3):635-45. doi: 10.1007/s00280-012-2050-4. Epub 2012 Dec 21.

PMID:: 23263160; [PubMed - indexed for MEDLINE]

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Select item 229276462.

Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor.

Lucki NC, Li D, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB.

Mol Cell Biol. 2012 Nov;32(21):4419-31. doi: 10.1128/MCB.00378-12. Epub 2012 Aug 27.

PMID:: 22927646; [PubMed - indexed for MEDLINE]

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Select item 227038803.

Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1.

Zhou J, Tawk M, Tiziano FD, Veillet J, Bayes M, Nolent F, Garcia V, Servidei S, Bertini E, Castro-Giner F, Renda Y, Carpentier S, Andrieu-Abadie N, Gut I, Levade T, Topaloglu H, Melki J.

Am J Hum Genet. 2012 Jul 13;91(1):5-14. doi: 10.1016/j.ajhg.2012.05.001. Epub 2012 Jun 14.

PMID:: 22703880; [PubMed - indexed for MEDLINE]

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Select item 225155194.

Acid ceramidase as a chemotherapeutic target to overcome resistance to the antitumoral effect of choline kinase α inhibition.

Ramírez de Molina A, de la Cueva A, Machado-Pinilla R, Rodriguez-Fanjul V, Gomez del Pulgar T, Cebrian A, Perona R, Lacal JC.

Curr Cancer Drug Targets. 2012 Jul;12(6):617-24.

PMID:: 22515519; [PubMed - indexed for MEDLINE]

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Select item 223492665.

DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.

Haynes TA, Filippov V, Filippova M, Yang J, Zhang K, Duerksen-Hughes PJ.

Biochim Biophys Acta. 2012 Jul;1821(7):943-53. doi: 10.1016/j.bbalip.2012.02.002. Epub 2012 Feb 11.

PMID:: 22349266; [PubMed - indexed for MEDLINE]

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Select item 223225906.

Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B.

Beckham TH, Lu P, Cheng JC, Zhao D, Turner LS, Zhang X, Hoffman S, Armeson KE, Liu A, Marrison T, Hannun YA, Liu X.

Int J Cancer. 2012 Nov 1;131(9):2034-43. doi: 10.1002/ijc.27480. Epub 2012 Mar 27.

PMID:: 22322590; [PubMed - indexed for MEDLINE]

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Select item 222618217.

Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression.

Lucki NC, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB.

Mol Endocrinol. 2012 Feb;26(2):228-43. doi: 10.1210/me.2011-1150. Epub 2012 Jan 19.

PMID:: 22261821; [PubMed - indexed for MEDLINE]

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Select item 219356018.

C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.

Flowers M, Fabriás G, Delgado A, Casas J, Abad JL, Cabot MC.

Breast Cancer Res Treat. 2012 Jun;133(2):447-58. doi: 10.1007/s10549-011-1768-8. Epub 2011 Sep 21.

PMID:: 21935601; [PubMed - indexed for MEDLINE]

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Select item 218933899.

Novel V97G ASAH1 mutation found in Farber disease patients: unique appearance of the disease with an intermediate severity, and marked early involvement of central and peripheral nervous system.

Chedrawi AK, Al-Hassnan ZN, Al-Muhaizea M, Colak D, Al-Younes B, Albakheet A, Tulba S, Kaya N.

Brain Dev. 2012 May;34(5):400-4. doi: 10.1016/j.braindev.2011.07.003. Epub 2011 Sep 3.

PMID:: 21893389; [PubMed - indexed for MEDLINE]

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Select item 2184672810.

Identification of cystatin SA as a novel inhibitor of acid ceramidase.

Eliyahu E, Shtraizent N, He X, Chen D, Shalgi R, Schuchman EH.

J Biol Chem. 2011 Oct 14;286(41):35624-33. doi: 10.1074/jbc.M111.260372. Epub 2011 Aug 16.

PMID:: 21846728; [PubMed - indexed for MEDLINE]

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Select item 2170070011.

Acid ceramidase expression modulates the sensitivity of A375 melanoma cells to dacarbazine.

Bedia C, Casas J, Andrieu-Abadie N, Fabriàs G, Levade T.

J Biol Chem. 2011 Aug 12;286(32):28200-9. doi: 10.1074/jbc.M110.216382. Epub 2011 Jun 23.

PMID:: 21700700; [PubMed - indexed for MEDLINE]

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Select item 2155727112.

Inhibition of acid ceramidase by a 2-substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N-(4-hydroxyphenyl) retinamide.

Gouazé-Andersson V, Flowers M, Karimi R, Fabriás G, Delgado A, Casas J, Cabot MC.

Prostate. 2011 Jul;71(10):1064-73. doi: 10.1002/pros.21321. Epub 2010 Dec 28.

PMID:: 21557271; [PubMed - indexed for MEDLINE]

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Select item 2149371013.

Genistein stimulates MCF-7 breast cancer cell growth by inducing acid ceramidase (ASAH1) gene expression.

Lucki NC, Sewer MB.

J Biol Chem. 2011 Jun 3;286(22):19399-409. doi: 10.1074/jbc.M110.195826. Epub 2011 Apr 14.

PMID:: 21493710; [PubMed - indexed for MEDLINE]

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Select item 2148704014.

IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia.

Hu X, Yang D, Zimmerman M, Liu F, Yang J, Kannan S, Burchert A, Szulc Z, Bielawska A, Ozato K, Bhalla K, Liu K.

Cancer Res. 2011 Apr 15;71(8):2882-91. doi: 10.1158/0008-5472.CAN-10-2493. Epub 2011 Apr 12.

PMID:: 21487040; [PubMed - indexed for MEDLINE]

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Select item 2137536415.

Identification of the N-acylsphingosine amidohydrolase 1 gene (ASAH1) for susceptibility to schizophrenia in a Han Chinese population.

Zhang H, Li D, Su Y, Jiang S, Xu Y, Jiang K, Cui D.

World J Biol Psychiatry. 2012 Feb;13(2):106-13. doi: 10.3109/15622975.2011.559273. Epub 2011 Mar 4.

PMID:: 21375364; [PubMed - indexed for MEDLINE]

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Select item 2133555516.

Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.

Jenkins RW, Clarke CJ, Canals D, Snider AJ, Gault CR, Heffernan-Stroud L, Wu BX, Simbari F, Roddy P, Kitatani K, Obeid LM, Hannun YA.

J Biol Chem. 2011 Apr 15;286(15):13292-303. doi: 10.1074/jbc.M110.163378. Epub 2011 Feb 18.

PMID:: 21335555; [PubMed - indexed for MEDLINE]

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Select item 2127701817.

A biodegradable amphiphilic and cationic triblock copolymer for the delivery of siRNA targeting the acid ceramidase gene for cancer therapy.

Mao CQ, Du JZ, Sun TM, Yao YD, Zhang PZ, Song EW, Wang J.

Biomaterials. 2011 Apr;32(11):3124-33. doi: 10.1016/j.biomaterials.2011.01.006. Epub 2011 Jan 28.

PMID:: 21277018; [PubMed - indexed for MEDLINE]

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Select item 2111628618.

Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide.

Turner LS, Cheng JC, Beckham TH, Keane TE, Norris JS, Liu X.

Prostate Cancer Prostatic Dis. 2011 Mar;14(1):30-7. doi: 10.1038/pcan.2010.47. Epub 2010 Nov 30.

PMID:: 21116286; [PubMed - indexed for MEDLINE]

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Select item 2087979719.

Serum autoantibody profiling using a natural glycoprotein microarray for the prognosis of early melanoma.

Liu Y, He J, Xie X, Su G, Teitz-Tennenbaum S, Sabel MS, Lubman DM.

J Proteome Res. 2010 Nov 5;9(11):6044-51. doi: 10.1021/pr100856k. Epub 2010 Oct 20.

PMID:: 20879797; [PubMed - indexed for MEDLINE]

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Select item 2060960320.

Farber lipogranulomatosis type 1--late presentation and early death in a Croatian boy with a novel homozygous ASAH1 mutation.

Cvitanovic-Sojat L, Gjergja Juraski R, Sabourdy F, Fensom AH, Fumic K, Paschke E, Levade T.

Eur J Paediatr Neurol. 2011 Mar;15(2):171-3. doi: 10.1016/j.ejpn.2010.06.002. Epub 2010 Jul 7.

PMID:: 20609603; [PubMed - indexed for MEDLINE]

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16 free full-text articles in PubMed Central

Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor. [Mol Cell Biol. 2012]
Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor.
Lucki NC, Li D, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB. Mol Cell Biol. 2012 Nov; 32(21):4419-31. Epub 2012 Aug 27.
Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1. [Am J Hum Genet. 2012]
Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1.
Zhou J, Tawk M, Tiziano FD, Veillet J, Bayes M, Nolent F, Garcia V, Servidei S, Bertini E, Castro-Giner F, et al. Am J Hum Genet. 2012 Jul 13; 91(1):5-14. Epub 2012 Jun 14.
Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. [Mol Endocrinol. 2012]
Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression.
Lucki NC, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB. Mol Endocrinol. 2012 Feb; 26(2):228-43. Epub 2012 Jan 19.

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