Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis.
Seneviratne D, Ma J, Tan X, Kwon YK, Muhammad E, Melhem M, DeFrances MC, Zarnegar R.
Seneviratne D, et al.
Gastroenterology. 2015 Jan;148(1):181-191.e17. doi: 10.1053/j.gastro.2014.09.019. Epub 2014 Sep 20.
Gastroenterology. 2015.
PMID: 25244939
Free PMC article.
METHODS: We genotyped human colon tumor tissues and adjacent nontumor tissues collected from 78 patients University of Pittsburgh Health Sciences and Veterans Hospital, along with 40 human CRC and adjacent nontumor tissues in a commercial microarray. ...
METHODS: We genotyped human colon tumor tissues and adjacent nontumor tissues collected from 78 patients University of Pitt …