Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Filters
Results by year
Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2010 | 1 |
2012 | 1 |
2014 | 1 |
2017 | 1 |
2024 | 0 |
Search Results
4 results
Results by year
Filters applied: . Clear all
The following terms were ignored: [, ]
The following terms were not found in PubMed: 3-dimethylmorpholin-4-yl
Page 1
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).
J Med Chem. 2017 May 25;60(10):4403-4423. doi: 10.1021/acs.jmedchem.7b00345. Epub 2017 May 15.
J Med Chem. 2017.
PMID: 28471663
Herein, we describe optimization of an initial hit 2, resulting in identification of racemic-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone 28, a potent irreversible inhibitor o …
Herein, we describe optimization of an initial hit 2, resulting in identification of racemic-trans-(3-((4-(aminomethyl)-6-(tri …
Novel agonists and antagonists for human protease activated receptor 2.
Barry GD, Suen JY, Le GT, Cotterell A, Reid RC, Fairlie DP.
Barry GD, et al.
J Med Chem. 2010 Oct 28;53(20):7428-40. doi: 10.1021/jm100984y.
J Med Chem. 2010.
PMID: 20873792
Item in Clipboard
Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110).
Suen JY, Barry GD, Lohman RJ, Halili MA, Cotterell AJ, Le GT, Fairlie DP.
Suen JY, et al.
Br J Pharmacol. 2012 Mar;165(5):1413-23. doi: 10.1111/j.1476-5381.2011.01610.x.
Br J Pharmacol. 2012.
PMID: 21806599
Free PMC article.
Item in Clipboard
Structure and putative signaling mechanism of Protease activated receptor 2 (PAR2) - a promising target for breast cancer.
Kakarala KK, Jamil K, Devaraji V.
Kakarala KK, et al.
J Mol Graph Model. 2014 Sep;53:179-199. doi: 10.1016/j.jmgm.2014.07.012. Epub 2014 Aug 7.
J Mol Graph Model. 2014.
PMID: 25173751
Item in Clipboard
Cite
Cite