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Chiral recognition between 1-(4-fluorophenyl)ethanol and 2-butanol: higher binding energy of homochiral complexes in the gas phase.
Rondino F, Paladini A, Ciavardini A, Casavola A, Catone D, Satta M, Barth HD, Giardini A, Speranza M, Piccirillo S. Rondino F, et al. Phys Chem Chem Phys. 2011 Jan 21;13(3):818-24. doi: 10.1039/c0cp01401j. Epub 2010 Dec 6. Phys Chem Chem Phys. 2011. PMID: 21132202 Free article.
Diastereomeric adducts between (S)-1-(4-fluorophenyl)-ethanol and R and S 2-butanol, formed by supersonic expansion, have been investigated by means of a combination of mass selected resonant two-photon ionization-spectroscopy and infrare …
Diastereomeric adducts between (S)-1-(4-fluorophenyl)-ethanol and R and S 2-butanol, formed by sup …
The Role of Presenilin-1 in the Excitotoxicity of Ethanol Withdrawal.
Jung ME, Metzger DB, Das HK. Jung ME, et al. J Pharmacol Exp Ther. 2016 Sep;358(3):516-26. doi: 10.1124/jpet.116.233361. Epub 2016 Jun 8. J Pharmacol Exp Ther. 2016. PMID: 27278235 Free PMC article.
Presenilin-1 (PS1) is a core component of gamma-secretase that is involved in neurodegeneration. ...We used the prefrontal cortex of male rats withdrawn from a chronic ethanol diet. Additionally, we used ethanol-withdrawn HT22 cells (mouse hippocampal) treate …
Presenilin-1 (PS1) is a core component of gamma-secretase that is involved in neurodegeneration. ...We used the prefrontal cortex of …
Optically active cyclohexene derivative as a new antisepsis agent: an efficient synthesis of ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242).
Yamada M, Ichikawa T, Yamano T, Kikumoto F, Nishikimi Y, Tamura N, Kitazaki T. Yamada M, et al. Chem Pharm Bull (Tokyo). 2006 Jan;54(1):58-62. doi: 10.1248/cpb.54.58. Chem Pharm Bull (Tokyo). 2006. PMID: 16394550 Free article.
Two new synthetic methods were established for the efficient synthesis of optically active cyclohexene antisepsis agent, ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate [(R)-1: TAK-242)]. The first method involved …
Two new synthetic methods were established for the efficient synthesis of optically active cyclohexene antisepsis agent, ethyl (6R)-6-[N-(2- …
Structure of droperidol-ethanol (1/1).
Klein CL, Welch J, Southall LC. Klein CL, et al. Acta Crystallogr C. 1989 Apr 15;45 ( Pt 4):650-3. doi: 10.1107/s0108270188013022. Acta Crystallogr C. 1989. PMID: 2610979
1-(1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,-3,6-tetrahydro-4-pyridyl)-1,3- dihydro-2H-benzimidazol-2-one ethanol solvate, C22H22FN3O2.C2H6O, Mr = 426.3, triclinic, P1, a = 6.083 (3), b = 10.296 (1), c = 16.018 (2) A, alpha = 1
1-(1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,-3,6-tetrahydro-4-pyridyl)-1,3- dihydro-2H-benzimidazol-2
Insecticidal and Repellent Properties of Rapid-Acting Fluorine-Containing Compounds against Aedes aegypti Mosquitoes.
Zhu X, Valbon W, Qiu M, Hu CT, Yang J, Erriah B, Jankowska M, Dong K, Ward MD, Kahr B. Zhu X, et al. ACS Infect Dis. 2023 Jul 14;9(7):1396-1407. doi: 10.1021/acsinfecdis.3c00161. Epub 2023 Jun 13. ACS Infect Dis. 2023. PMID: 37311068 Free PMC article.
Incorporating fluorine can dramatically alter the physiochemical properties and bioavailability of insecticides. For example, 1,1,1-trichloro-2,2-bis(4-fluorophenyl)ethane (DFDT)a difluoro congener of trichloro-2,2-bis(4-chlorophenyl)ethane (DDT …
Incorporating fluorine can dramatically alter the physiochemical properties and bioavailability of insecticides. For example, 1,1
Development and Validation of a Rapid Method for Identification of New Synthetic Cannabinoids in Hair Based on High-Performance Liquid Chromatography-Ion Trap Mass Spectrometry Using a Simplified User Interface.
Musile G, Palacio C, Murari M, Appolonova S, Tagliaro F. Musile G, et al. J Anal Toxicol. 2023 Feb 21;47(1):72-80. doi: 10.1093/jat/bkac027. J Anal Toxicol. 2023. PMID: 35536611
After a washing step with dichloromethane, hair (about 50 mg) was incubated for 3 h with 1.5 mL ethanol. One milliliter of this solution was then dried, reconstituted with mobile phase and injected. ...The method was validated according to international guidelines o …
After a washing step with dichloromethane, hair (about 50 mg) was incubated for 3 h with 1.5 mL ethanol. One milliliter of thi …
Fungicide dissipation and impact on metolachlor aerobic soil degradation and soil microbial dynamics.
White PM, Potter TL, Culbreath AK. White PM, et al. Sci Total Environ. 2010 Feb 15;408(6):1393-402. doi: 10.1016/j.scitotenv.2009.11.012. Epub 2009 Dec 16. Sci Total Environ. 2010. PMID: 20015538
Our study objective was to determine the effects of 4 peanut fungicides, chlorothalonil (2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile), tebuconazole (alpha-[2-(4-chlorophenyl)ethyl]-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol), …
Our study objective was to determine the effects of 4 peanut fungicides, chlorothalonil (2,4,5,6-tetrachloro-1,3-benzenedicarbonitril …
The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and endothelial dysfunction.
Martelli A, Testai L, Anzini M, Cappelli A, Di Capua A, Biava M, Poce G, Consalvi S, Giordani A, Caselli G, Rovati L, Ghelardini C, Patrignani P, Sautebin L, Breschi MC, Calderone V. Martelli A, et al. Pharmacol Res. 2013 Dec;78:1-9. doi: 10.1016/j.phrs.2013.09.008. Epub 2013 Sep 29. Pharmacol Res. 2013. PMID: 24083950
Synthesis, Computational and cytotoxicity studies of aryl hydrazones of β-diketones: Selective Ni2+ metal Responsive fluorescent chemosensors.
Subhasri A, Balachandran S, Mohanraj K, Kumar PS, Jothi KJ, Anbuselvan C. Subhasri A, et al. Chemosphere. 2022 Jun;297:134150. doi: 10.1016/j.chemosphere.2022.134150. Epub 2022 Mar 2. Chemosphere. 2022. PMID: 35247452
A new fluorescent sensor 2-(2-(3-chloro-4-fluorophenyl)hydrazono)-5,5-dimethyl cyclohexane-1,3-dione (A) and 2-(2-(4-chloro-2-nitrophenyl)hydrazono)-5,5-dimethyl cyclohexane-1,3-dione (B) composed of a beta-diketones of aryl hydrazones synthesized by s …
A new fluorescent sensor 2-(2-(3-chloro-4-fluorophenyl)hydrazono)-5,5-dimethyl cyclohexane-1,3-dione (A) and 2-(2-(4-ch …
The beta3-adrenoceptor agonist 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]-phenyl]-benzenesulfonamide (L755507) and antagonist (S)-N-[4-[2-[[3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]-ethyl]phenyl]benzenesulfonamide (L748337) activate different signaling pathways in Chinese hamster ovary-K1 cells stably expressing the human beta3-adrenoceptor.
Sato M, Hutchinson DS, Evans BA, Summers RJ. Sato M, et al. Mol Pharmacol. 2008 Nov;74(5):1417-28. doi: 10.1124/mol.108.046979. Epub 2008 Aug 6. Mol Pharmacol. 2008. PMID: 18684840
Maximal cAMP accumulation with zinterol and L755507 was increased after pretreatment with pertussis toxin, indicating that the human beta(3)-AR couples to G(i) and to G(s). In contrast to cAMP, zinterol, L755507 and L748337 increased phosphorylation of extracellular signal …
Maximal cAMP accumulation with zinterol and L755507 was increased after pretreatment with pertussis toxin, indicating that the human beta(3) …
34 results