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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 1
1949 2
1950 2
1951 4
1952 2
1953 3
1954 3
1955 1
1957 3
1958 4
1959 1
1960 6
1961 3
1962 3
1963 2
1964 6
1965 3
1967 1
1968 2
1969 9
1970 5
1971 6
1972 10
1973 5
1974 4
1975 5
1976 13
1977 17
1978 15
1979 18
1980 25
1981 26
1982 35
1983 46
1984 49
1985 49
1986 40
1987 35
1988 46
1989 41
1990 36
1991 46
1992 61
1993 60
1994 66
1995 66
1996 66
1997 104
1998 110
1999 185
2000 270
2001 280
2002 367
2003 407
2004 445
2005 493
2006 555
2007 606
2008 630
2009 691
2010 772
2011 818
2012 911
2013 934
2014 1025
2015 1016
2016 1057
2017 1129
2018 1166
2019 1226
2020 1326
2021 1382
2022 1395
2023 1118
2024 330

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19,150 results

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Page 1
Effects of (-)-epicatechin on mitochondria.
Daussin FN, Heyman E, Burelle Y. Daussin FN, et al. Nutr Rev. 2021 Jan 1;79(1):25-41. doi: 10.1093/nutrit/nuaa094. Nutr Rev. 2021. PMID: 32989466 Free article. Review.
Natural compounds are widely used for multiple indications, and their broad healing properties suggest that several may improve mitochondrial function. This review focuses on (-)-epicatechin, a monomeric flavanol, and its effects on mitochondria. The review summarizes the …
Natural compounds are widely used for multiple indications, and their broad healing properties suggest that several may improve mitochondria …
( -)-Epicatechin and cardiometabolic risk factors: a focus on potential mechanisms of action.
Hid EJ, Mosele JI, Prince PD, Fraga CG, Galleano M. Hid EJ, et al. Pflugers Arch. 2022 Jan;474(1):99-115. doi: 10.1007/s00424-021-02640-0. Epub 2021 Nov 23. Pflugers Arch. 2022. PMID: 34812946 Review.
This review summarizes experimental evidence on the beneficial effects of ( -)-epicatechin (EC) attenuating major cardiometabolic risk factors, i.e., dyslipidemias, obesity (adipose tissue dysfunction), hyperglycemia (insulin resistance), and hypertension (endothelial dysf …
This review summarizes experimental evidence on the beneficial effects of ( -)-epicatechin (EC) attenuating major cardiometabolic ris …
Epicatechin-assembled nanoparticles against renal ischemia/reperfusion injury.
Zhang J, Xie H, Wang T, Zhang H, Yang Z, Yang P, Li Y, Ma X, Gu Z. Zhang J, et al. J Mater Chem B. 2022 Sep 21;10(36):6965-6973. doi: 10.1039/d2tb01301k. J Mater Chem B. 2022. PMID: 36000287
Bioinspired and biosafety antioxidant nanoparticle assemblies from natural occurring molecules have been regarded as a class of effective therapeutic nanomaterials for addressing current inflammatory diseases such as acute kidney injury. In this study, a series of epicatechin
Bioinspired and biosafety antioxidant nanoparticle assemblies from natural occurring molecules have been regarded as a class of effective th …
Absorption, metabolism, distribution and excretion of (-)-epicatechin: A review of recent findings.
Borges G, Ottaviani JI, van der Hooft JJJ, Schroeter H, Crozier A. Borges G, et al. Mol Aspects Med. 2018 Jun;61:18-30. doi: 10.1016/j.mam.2017.11.002. Epub 2017 Nov 9. Mol Aspects Med. 2018. PMID: 29126853 Review.
Studies have shown that [2-(14)C](-)-epicatechin is absorbed in the small intestine with the 12 structural-related (-)-epicatechin metabolites (SREMs), mainly in the form of (-)-epicatechin-3'-O-glucuronide, 3'-O-methyl-(-)-epicatechin-5-sulfate and (- …
Studies have shown that [2-(14)C](-)-epicatechin is absorbed in the small intestine with the 12 structural-related (-)-epicatechin
(-)-Epicatechin Improves Vasoreactivity and Mitochondrial Respiration in Thermoneutral-Housed Wistar Rat Vasculature.
Chun JH, Henckel MM, Knaub LA, Hull SE, Pott GB, Walker LA, Reusch JE, Keller AC. Chun JH, et al. Nutrients. 2022 Mar 5;14(5):1097. doi: 10.3390/nu14051097. Nutrients. 2022. PMID: 35268072 Free PMC article.

AMPK and CaMKIIalpha and beta expression were lessened with ()-epicatechin treatment in those housed at thermoneutrality (p < 0.05). The opposite was observed with animals housed at room temperature supplemented with ()-epicatechin. These data illustrate a contex

AMPK and CaMKIIalpha and beta expression were lessened with ()-epicatechin treatment in those housed at thermoneutrality (p < 0.05

Epicatechin influences primary hemostasis, coagulation and fibrinolysis.
Sinegre T, Teissandier D, Milenkovic D, Morand C, Lebreton A. Sinegre T, et al. Food Funct. 2019 Nov 1;10(11):7291-7298. doi: 10.1039/c9fo00816k. Epub 2019 Oct 17. Food Funct. 2019. PMID: 31621731
Plasma samples from 10 healthy volunteers were spiked with increasing concentrations of epicatechin (1 to 100 muM). Epicatechin effect on primary hemostasis, coagulation and fibrinolysis was assessed by measuring platelet aggregation using light transmission aggrego …
Plasma samples from 10 healthy volunteers were spiked with increasing concentrations of epicatechin (1 to 100 muM). Epicatechin
Green Tea Catechins: Nature's Way of Preventing and Treating Cancer.
Farhan M. Farhan M. Int J Mol Sci. 2022 Sep 14;23(18):10713. doi: 10.3390/ijms231810713. Int J Mol Sci. 2022. PMID: 36142616 Free PMC article. Review.
Catechins have the ability to effectively neutralize reactive oxygen species. The catechin derivatives of green tea include epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG) and epigallocatechin gallate (EGCG). ...
Catechins have the ability to effectively neutralize reactive oxygen species. The catechin derivatives of green tea include epicat
Epicatechin exerts dual action to shield sickling and hydroxyurea-induced myelosuppression: Implication in sickle cell anemia management.
Gour A, Kour D, Dogra A, Manhas D, Wazir P, Digra SK, Kumar A, Nandi U. Gour A, et al. Toxicol Appl Pharmacol. 2022 Aug 15;449:116113. doi: 10.1016/j.taap.2022.116113. Epub 2022 Jun 9. Toxicol Appl Pharmacol. 2022. PMID: 35691369
A panel of experiments were performed at first to observe epicatechin's effect on sickling and hemolytic behaviour using SCA patient's blood (ex vivo). ...Epicatechin exhibited potent action on anti-sickling, polymerization inhibition, and erythrocyte membrane stabi …
A panel of experiments were performed at first to observe epicatechin's effect on sickling and hemolytic behaviour using SCA patient' …
(-)-Epicatechin Reduces Neuroinflammation, Protects Mitochondria Function, and Prevents Cognitive Impairment in Sepsis-Associated Encephalopathy.
Ling J, Wu Y, Zou X, Chang Y, Li G, Fang M. Ling J, et al. Oxid Med Cell Longev. 2022 May 24;2022:2657713. doi: 10.1155/2022/2657713. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35656027 Free PMC article.
In sepsis-associated encephalopathy, neuroinflammatory overactivation and mitochondrial damage are thought to contribute to cognitive and behavioral impairments. In this study, we found that administration of (-)-Epicatechin, a dietary flavonoid of the flavan-3-ol subgroup …
In sepsis-associated encephalopathy, neuroinflammatory overactivation and mitochondrial damage are thought to contribute to cognitive and be …
19,150 results
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