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Did you mean (+)-fargesii (162 results)?
Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-kappaB pathways.
Lu J, Zhang H, Pan J, Hu Z, Liu L, Liu Y, Yu X, Bai X, Cai D, Zhang H. Lu J, et al. Arthritis Res Ther. 2021 May 14;23(1):142. doi: 10.1186/s13075-021-02512-z. Arthritis Res Ther. 2021. PMID: 33990219 Free PMC article.
Conditioned medium (CM) from M1 macrophages treated with fargesin reduced the expression of matrix metalloproteinase-13, RUNX2, and type X collagen and increased Col2a1 and SOX9 in OA chondrocytes, but fargesin alone did not affect chondrocyte catabolic processes. M …
Conditioned medium (CM) from M1 macrophages treated with fargesin reduced the expression of matrix metalloproteinase-13, RUNX2, and t …
Fargesin alleviates atherosclerosis by promoting reverse cholesterol transport and reducing inflammatory response.
Wang G, Gao JH, He LH, Yu XH, Zhao ZW, Zou J, Wen FJ, Zhou L, Wan XJ, Tang CK. Wang G, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 May;1865(5):158633. doi: 10.1016/j.bbalip.2020.158633. Epub 2020 Jan 25. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 31988050
BACKGROUND AND AIMS: Fargesin mainly functions in the improvement of lipid metabolism and the inhibition of inflammation, but the role of fargesin in atherogenesis and the molecular mechanisms have not been defined. ...Further, fargesin reduced lipid accumula …
BACKGROUND AND AIMS: Fargesin mainly functions in the improvement of lipid metabolism and the inhibition of inflammation, but the rol …
Protective effects of fargesin on cadmium-induced lung injury through regulating aryl hydrocarbon receptor.
Zhang Y, Ma R, Wang J. Zhang Y, et al. J Biochem Mol Toxicol. 2022 Nov;36(11):e23197. doi: 10.1002/jbt.23197. Epub 2022 Aug 19. J Biochem Mol Toxicol. 2022. PMID: 35983679
Furthermore, fargesin inhibited cadmium-induced NF-kappaB activation. In addition, fargesin was found to increase AhR expression. In conclusion, fargesin attenuates cadmium-induced lung injury may be via activating AhR, which subsequently suppressing the infl …
Furthermore, fargesin inhibited cadmium-induced NF-kappaB activation. In addition, fargesin was found to increase AhR expressi …
Fargesin inhibits melanin synthesis in murine malignant and immortalized melanocytes by regulating PKA/CREB and P38/MAPK signaling pathways.
Fu T, Chai B, Shi Y, Dang Y, Ye X. Fu T, et al. J Dermatol Sci. 2019 Apr;94(1):213-219. doi: 10.1016/j.jdermsci.2019.03.004. Epub 2019 Mar 28. J Dermatol Sci. 2019. PMID: 30956031
BACKGROUND: Fargesin is commonly used in the treatment of allergic rhinitis, inflammation, sinusitis and headache. ...Zebrafish was used as an in vivo model for studying the function of fargesin in regulating melanogenesis. RESULTS: Fargesin effectively inhib …
BACKGROUND: Fargesin is commonly used in the treatment of allergic rhinitis, inflammation, sinusitis and headache. ...Zebrafish was u …
Fargesin Inhibits EGF-Induced Cell Transformation and Colon Cancer Cell Growth by Suppression of CDK2/Cyclin E Signaling Pathway.
Lee GE, Lee CJ, An HJ, Kang HC, Lee HS, Lee JY, Oh SR, Cho SJ, Kim DJ, Cho YY. Lee GE, et al. Int J Mol Sci. 2021 Feb 19;22(4):2073. doi: 10.3390/ijms22042073. Int J Mol Sci. 2021. PMID: 33669811 Free PMC article.
Although the lignan compound fargesin is a major ingredient in Shin-Yi, the roles of fargesin in carcinogenesis and cancer cell growth have not been elucidated. ...Unexpectedly, we found that signaling pathway analyses showed different regulation patterns in which …
Although the lignan compound fargesin is a major ingredient in Shin-Yi, the roles of fargesin in carcinogenesis and cancer cel …
Natural product fargesin interferes with H3 histone lactylation via targeting PKM2 to inhibit non-small cell lung cancer tumorigenesis.
Guo Z, Tang Y, Wang S, Huang Y, Chi Q, Xu K, Xue L. Guo Z, et al. Biofactors. 2023 Dec 27. doi: 10.1002/biof.2031. Online ahead of print. Biofactors. 2023. PMID: 38149461
There is an urgent need to find more effective drugs that inhibit NSCLC. Fargesin (FGS) has demonstrated anti-tumor effects; however, its efficacy and the molecular mechanism of inhibiting NSCLC are unclear. ...
There is an urgent need to find more effective drugs that inhibit NSCLC. Fargesin (FGS) has demonstrated anti-tumor effects; however, …
Flos magnoliae constituent fargesin has an anti-allergic effect via ORAI1 channel inhibition.
Hong PTL, Kim HJ, Kim WK, Nam JH. Hong PTL, et al. Korean J Physiol Pharmacol. 2021 May 1;25(3):251-258. doi: 10.4196/kjpp.2021.25.3.251. Korean J Physiol Pharmacol. 2021. PMID: 33859065 Free PMC article.
Therefore, we investigated which of the five major constituents of 30% ethanoic FM (vanillic acid, tiliroside, eudesmin, magnolin, and fargesin) inhibit SOCE and their physiological effects on immune cells. ...Our findings suggest that fargesin can be a promising ca …
Therefore, we investigated which of the five major constituents of 30% ethanoic FM (vanillic acid, tiliroside, eudesmin, magnolin, and fa …
Fargesin as a potential beta1 adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis.
Wang X, Cheng Y, Xue H, Yue Y, Zhang W, Li X. Wang X, et al. Fitoterapia. 2015 Sep;105:16-25. doi: 10.1016/j.fitote.2015.05.016. Epub 2015 May 27. Fitoterapia. 2015. PMID: 26025856
To provide more biological information about fargesin, we investigated the effects of fargesin on isoproterenol-(ISO-) induced cells injury in the high expression beta1 adrenergic receptor/Chinese hamster ovary-S (beta1AR/CHO-S) cells and occluding the left coronary …
To provide more biological information about fargesin, we investigated the effects of fargesin on isoproterenol-(ISO-) induced …
Anti-Inflammatory Effects of Fargesin on Chemically Induced Inflammatory Bowel Disease in Mice.
Yue B, Ren YJ, Zhang JJ, Luo XP, Yu ZL, Ren GY, Sun AN, Deng C, Wang ZT, Dou W. Yue B, et al. Molecules. 2018 Jun 7;23(6):1380. doi: 10.3390/molecules23061380. Molecules. 2018. PMID: 29880739 Free PMC article.
We sought to investigate whether fargesin ameliorates experimental inflammatory bowel disease (IBD) in mice. ...The findings may contribute to the development of therapies for human IBD by using fargesin or its derivatives....
We sought to investigate whether fargesin ameliorates experimental inflammatory bowel disease (IBD) in mice. ...The findings may cont …
Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice.
Lee YS, Cha BY, Choi SS, Harada Y, Choi BK, Yonezawa T, Teruya T, Nagai K, Woo JT. Lee YS, et al. Biofactors. 2012 Jul-Aug;38(4):300-8. doi: 10.1002/biof.1022. Epub 2012 Jun 2. Biofactors. 2012. PMID: 22674784
Fargesin promoted the glucose uptake in 3T3-L1 adipocytes. In HFD-induced obese mice, fargesin decreased the body weight gain, white adipose tissue (WAT), and plasma triglyceride, non-esterified fatty acid and glucose levels, and improved the glucose tolerance. ...T …
Fargesin promoted the glucose uptake in 3T3-L1 adipocytes. In HFD-induced obese mice, fargesin decreased the body weight gain, …
62 results