Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data.
Li S, Schmid KT, de Vries DH, Korshevniuk M, Losert C, Oelen R, van Blokland IV; BIOS Consortium, sc-eQTLgen Consortium; Groot HE, Swertz MA, van der Harst P, Westra HJ, van der Wijst MGP, Heinig M, Franke L.
Li S, et al.
Genome Biol. 2023 Apr 18;24(1):80. doi: 10.1186/s13059-023-02897-x.
Genome Biol. 2023.
PMID: 37072791
Free PMC article.
One co-eQTL SNP, rs1131017, that is associated with several autoimmune diseases, affects the co-expression of RPS26 with other ribosomal genes. Interestingly, specifically in T cells, the SNP additionally affects co-expression of RPS26 and a group of genes associate …
One co-eQTL SNP, rs1131017, that is associated with several autoimmune diseases, affects the co-expression of RPS26 with other riboso …