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Page 1
Continuous Subcutaneous Foslevodopa/Foscarbidopa in Parkinson's Disease: Safety and Efficacy Results From a 12-Month, Single-Arm, Open-Label, Phase 3 Study.
Aldred J, Freire-Alvarez E, Amelin AV, Antonini A, Bergmans B, Bergquist F, Bouchard M, Budur K, Carroll C, Chaudhuri KR, Criswell SR, Danielsen EH, Gandor F, Jia J, Kimber TE, Mochizuki H, Robieson WZ, Spiegel AM, Standaert DG, Talapala S, Facheris MF, Fung VSC. Aldred J, et al. Neurol Ther. 2023 Dec;12(6):1937-1958. doi: 10.1007/s40120-023-00533-1. Epub 2023 Aug 26. Neurol Ther. 2023. PMID: 37632656 Free PMC article.
Secondary endpoints included changes from baseline in normalized "Off" and "On" time, percentage of patients reporting morning akinesia, Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Parkinson's Disease Sleep Scale-2 (PDSS-2), 39-item Parkinson's …
Secondary endpoints included changes from baseline in normalized "Off" and "On" time, percentage of patients reporting morning akinesia, Mov …
Angina After Percutaneous Coronary Intervention: Patient and Procedural Predictors.
Collison D, Copt S, Mizukami T, Collet C, McLaren R, Didagelos M, Aetesam-Ur-Rahman M, McCartney P, Ford TJ, Lindsay M, Shaukat A, Rocchiccioli P, Brogan R, Watkins S, McEntegart M, Good R, Robertson K, O'Boyle P, Davie A, Khan A, Hood S, Eteiba H, Berry C, Oldroyd KG. Collison D, et al. Circ Cardiovasc Interv. 2023 Apr;16(4):e012511. doi: 10.1161/CIRCINTERVENTIONS.122.012511. Epub 2023 Mar 28. Circ Cardiovasc Interv. 2023. PMID: 36974680 Free PMC article. Clinical Trial.
Compared with patients with no angina at follow-up, they had lower baseline SAQ summary scores (69.4824.12 versus 50.2022.59, P<0.001) and EQ-5D-5L health index scores (0.840.15 versus 0.690.22, P<0.001). Pre-PCI fractional flow reserve (FFR) was lower among p …
Compared with patients with no angina at follow-up, they had lower baseline SAQ summary scores (69.4824.12 versus 50.2022.59, P<0.001) an …
Patient-reported outcome measures for adult chronic rhinosinusitis: A systematic review and quality assessment.
Rudmik L, Hopkins C, Peters A, Smith TL, Schlosser RJ, Soler ZM. Rudmik L, et al. J Allergy Clin Immunol. 2015 Dec;136(6):1532-1540.e2. doi: 10.1016/j.jaci.2015.10.012. J Allergy Clin Immunol. 2015. PMID: 26654198 Review.
Overall, the highest quality validated PROMs for adults with CRS were (1) the 22-item Sinonasal Outcome Test (19 points), (2) the Questionnaire of Olfactory Disorders (14 points), (3) the Sinusitis Control Test (14 points), and (4) the EQ-5D (13 points). Most of the …
Overall, the highest quality validated PROMs for adults with CRS were (1) the 22-item Sinonasal Outcome Test (19 points), (2) the Que …
Cross-cultural adaptation and validation of simplified Chinese version of the Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ) 2.0 with its assessment in clinical setting.
Yin M, Sun Z, Ding X, Wang T, Sun Y, Li L, Gao X, Ma J, Huang Q, Xiao J, Mo W. Yin M, et al. Spine J. 2022 Dec;22(12):2024-2032. doi: 10.1016/j.spinee.2022.08.013. Epub 2022 Aug 26. Spine J. 2022. PMID: 36031097
The relationship among the SC-SOSGOQ 2.0, SC-EQ-5D-5L and SC-SF-36 was assessed using the correlation coefficients. ...Concurrent assessment of criterion validity demonstrated a moderate-to-strong correlation in all domains of SC-SOSGOQ 2.0 with …
The relationship among the SC-SOSGOQ 2.0, SC-EQ-5D-5L and SC-SF-36 was assessed using the correlation coefficien …
Emergent magnetism at transition-metal-nanocarbon interfaces.
Al Ma'Mari F, Rogers M, Alghamdi S, Moorsom T, Lee S, Prokscha T, Luetkens H, Valvidares M, Teobaldi G, Flokstra M, Stewart R, Gargiani P, Ali M, Burnell G, Hickey BJ, Cespedes O. Al Ma'Mari F, et al. Proc Natl Acad Sci U S A. 2017 May 30;114(22):5583-5588. doi: 10.1073/pnas.1620216114. Epub 2017 May 15. Proc Natl Acad Sci U S A. 2017. PMID: 28507160 Free PMC article.
Here, we investigate the origin of the magnetism arising at these interfaces by using different techniques to probe 3d and 5d metal films such as Sc, Mn, Cu, and Pt in contact with fullerenes and rf-sputtered carbon layers. These systems exhibit small anisotropy and …
Here, we investigate the origin of the magnetism arising at these interfaces by using different techniques to probe 3d and 5d metal f …
Anion photoelectron spectroscopy of free [Au(25)(SC(12)H(25))(18)]().
Hirata K, Yamashita K, Muramatsu S, Takano S, Ohshimo K, Azuma T, Nakanishi R, Nagata T, Yamazoe S, Koyasu K, Tsukuda T. Hirata K, et al. Nanoscale. 2017 Sep 21;9(36):13409-13412. doi: 10.1039/c7nr04641c. Nanoscale. 2017. PMID: 28861577
Nevertheless, no direct information is available on the energy levels and densities of occupied states. Here, we report the photoelectron spectrum of [Au(25)(SC(12)H(25))(18)](-) isolated under vacuum for the first time. The spectrum exhibits two distinct peaks, correspond …
Nevertheless, no direct information is available on the energy levels and densities of occupied states. Here, we report the photoelectron sp …
Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Children and Adolescents With COVID-19 or Multisystem Inflammatory Syndrome Admitted to U.S. ICUs.
Bembea MM, Loftis LL, Thiagarajan RR, Young CC, McCadden TP, Newhams MM, Kucukak S, Mack EH, Fitzgerald JC, Rowan CM, Maddux AB, Kolmar AR, Irby K, Heidemann S, Schwartz SP, Kong M, Crandall H, Havlin KM, Singh AR, Schuster JE, Hall MW, Wellnitz KA, Maamari M, Gaspers MG, Nofziger RA, Lim PPC, Carroll RW, Coronado Munoz A, Bradford TT, Cullimore ML, Halasa NB, McLaughlin GE, Pannaraj PS, Cvijanovich NZ, Zinter MS, Coates BM, Horwitz SM, Hobbs CV, Dapul H, Graciano AL, Butler AD, Patel MM, Zambrano LD, Campbell AP, Randolph AG; Overcoming COVID-19 Investigators. Bembea MM, et al. Pediatr Crit Care Med. 2023 May 1;24(5):356-371. doi: 10.1097/PCC.0000000000003212. Epub 2023 Mar 30. Pediatr Crit Care Med. 2023. PMID: 36995097 Free PMC article.
The body mass index percentile was similar in the MIS-C ECMO versus no ECMO groups (89.9 vs 85.8; p = 0.22) but higher in the COVID-19 ECMO versus no ECMO groups (98.3 vs 96.5; p = 0.03). ...
The body mass index percentile was similar in the MIS-C ECMO versus no ECMO groups (89.9 vs 85.8; p = 0.22) but higher in the COVID-1 …
Effects of Microorganisms on Growth Performance, Body Composition, Digestive Enzyme Activity, Intestinal Bacteria Flora and Antimicrobial Peptide (AMP) Content of Black Soldier Fly Larvae (Hermetia illucens).
Meng Y, Zhang X, Zhang Z, Li J, Zheng P, Li J, Xu J, Xian J, Lu Y. Meng Y, et al. Animals (Basel). 2023 Aug 26;13(17):2722. doi: 10.3390/ani13172722. Animals (Basel). 2023. PMID: 37684985 Free PMC article.
Therefore, RP was selected to prepare the diets and was incorporated into diets for H. illucens at levels of 0 (R0), 1.22 10(6) (R1), 1.22 10(7) (R2), 1.22 10(8) (R3), 1.22 10(9) (R4) and 1.22 10(10) (R5) CFU/g. ...Therefore, RP is superior to t …
Therefore, RP was selected to prepare the diets and was incorporated into diets for H. illucens at levels of 0 (R0), 1.22 10(6) (R1), …
Factors associated with health-related quality of life in patients with Crohn's disease in Iran: A prospective observational study.
Karami H, Shirvani Shiri M, Ebadi Fard Azar F, Bagheri Lankarani K, Ghahramani S, Rezapour A, Tatari M, Heidari Javargi Z. Karami H, et al. Front Med (Lausanne). 2023 Jan 19;9:1091330. doi: 10.3389/fmed.2022.1091330. eCollection 2022. Front Med (Lausanne). 2023. PMID: 36760884 Free PMC article.
Employment, having "other chronic diseases," and ADA consumption were the most important independent predictors of HRQoL in CD patients, [beta = 0.21 (EQ-5D index), beta = 19.61 (EQ-VAS), beta = 12.26 (IBDQ-9), OR: 0.09 (MO), OR: 0.12 (UA), OR: 0.21 (P/D), OR: 0.22 …
Employment, having "other chronic diseases," and ADA consumption were the most important independent predictors of HRQoL in CD patients, [be …
Pharmacokinetics of Buprenorphine and Sustained-release Buprenorphine in Common Marmosets (Callithrix jacchus).
Fitz CB, Goodroe AE, Moody DE, Fang WB, Capuano SV III. Fitz CB, et al. J Am Assoc Lab Anim Sci. 2021 Mar 1;60(2):188-194. doi: 10.30802/AALAS-JAALAS-20-000082. Epub 2020 Dec 29. J Am Assoc Lab Anim Sci. 2021. PMID: 33375952 Free PMC article.
Equal numbers of each sex were randomly assigned to receive BUP (0.02 mg/kg IM) or BSR (0.2 mg/kg SC), resulting in peak plasma concentrations (mean 1 SD) of 15.2 8.1 and 2.8 1.2 ng/mL, terminal phase t(1/2) of 2.2 1.0 and 32.6 9.6 h, and AUC(0-last) of 16.1 3.7 and 98.6 4 …
Equal numbers of each sex were randomly assigned to receive BUP (0.02 mg/kg IM) or BSR (0.2 mg/kg SC), resulting in peak plasma conce …
55 results