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Patient-reported outcomes in capmatinib-treated patients with METex14-mutated advanced NSCLC: Results from the GEOMETRY mono-1 study.
Wolf J, Garon EB, Groen HJM, Tan DSW, Gilloteau I, Le Mouhaer S, Hampe M, Cai C, Chassot-Agostinho A, Reynolds M, Sherif B, Heist RS. Wolf J, et al. Eur J Cancer. 2023 Apr;183:98-108. doi: 10.1016/j.ejca.2022.10.030. Epub 2022 Dec 10. Eur J Cancer. 2023. PMID: 36822130
PROs were collected at baseline and every six weeks thereafter using EORTC QLQ-C30 global health status/quality of life (GHS/QoL), QLQ-LC13 symptoms, and EQ-5D-5L visual analogue scale (VAS) questionnaires. RESULTS: As of 6 January 2020, 27/28 1L and 65/69 2L(+) patients h …
PROs were collected at baseline and every six weeks thereafter using EORTC QLQ-C30 global health status/quality of life (GHS/QoL), QLQ-LC13 …
Quality of Life After Fractional Flow Reserve-Guided PCI Compared With Coronary Bypass Surgery.
Fearon WF, Zimmermann FM, Ding VY, Zelis JM, Piroth Z, Davidavicius G, Mansour S, Kharbanda R, Östlund-Papadogeorgos N, Oldroyd KG, Wendler O, Reardon MJ, Woo YJ, Yeung AC, Pijls NHJ, De Bruyne B, Desai M, Hlatky MA; FAME 3 Investigators. Fearon WF, et al. Circulation. 2022 May 31;145(22):1655-1662. doi: 10.1161/CIRCULATIONAHA.122.060049. Epub 2022 Apr 2. Circulation. 2022. PMID: 35369704 Free article. Clinical Trial.
The primary objective was to compare EQ-5D summary index at 12 months. Secondary end points included angina grade and work status. ...The trajectory of EQ-5D during the 12 months differed (P<0.001) between PCI and CABG: at 1 month, EQ-5D was 0.063 (95% CI, …
The primary objective was to compare EQ-5D summary index at 12 months. Secondary end points included angina grade and work status. .. …
Comparing the Performance of 2 Health Utility Measures in the Medicare Health Outcome Survey (HOS).
Jia H, Lubetkin EI, DeMichele K, Stark DS, Zack MM, Thompson WW. Jia H, et al. Med Decis Making. 2018 Nov;38(8):983-993. doi: 10.1177/0272989X18808494. Med Decis Making. 2018. PMID: 30403580
BACKGROUND: The Medicare Health Outcomes Survey (HOS), a nationwide annual survey of Medicare beneficiaries, includes the Centers for Disease Control and Prevention's HRQOL-4 questionnaire and Veterans RAND 12-item Health Survey (VR-12). This study compared EQ-5D scores de …
BACKGROUND: The Medicare Health Outcomes Survey (HOS), a nationwide annual survey of Medicare beneficiaries, includes the Centers for Diseas …
The efficacy and safety of intravesical chondroitin sulphate solution in recurrent urinary tract infections.
Rahnama'i MS, Javan Balegh Marand A, Röschmann-Doose K, Steffens L, Arendsen HJ. Rahnama'i MS, et al. BMC Urol. 2022 Nov 23;22(1):188. doi: 10.1186/s12894-022-01149-7. BMC Urol. 2022. PMID: 36424583 Free PMC article.
Patients filled in a standardized quality of life questionnaire (EQ-5D). RESULTS: We found a statistically significant reduction of number of infections from 7.10 0.50 SEM to 0.45 0.07 SEM after 12 months therapy with CS compared to 12 months therapy with LDLTAB (from 7.04 …
Patients filled in a standardized quality of life questionnaire (EQ-5D). RESULTS: We found a statistically significant reduction of n …
Patient-reported outcomes during repetitive oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for isolated unresectable colorectal peritoneal metastases in a multicenter, single-arm, phase 2 trial (CRC-PIPAC).
Lurvink RJ, Rovers KP, Wassenaar ECE, Bakkers C, Burger JWA, Creemers GM, Los M, Mols F, Wiezer MJ, Nienhuijs SW, Boerma D, de Hingh IHJT. Lurvink RJ, et al. Surg Endosc. 2022 Jun;36(6):4486-4498. doi: 10.1007/s00464-021-08802-6. Epub 2021 Nov 10. Surg Endosc. 2022. PMID: 34757489 Free PMC article. Clinical Trial.
METHODS: In this single-arm phase 2 trial in two tertiary centers, patients with isolated unresectable CPM received 6-weekly PIPAC-OX (92 mg/m(2)). PROs (calculated from EQ-5D-5L, and EORTC QLQ-C30 and QLQ-CR29) were compared between baseline and 1 and 4 weeks after the fi …
METHODS: In this single-arm phase 2 trial in two tertiary centers, patients with isolated unresectable CPM received 6-weekly PIPAC-OX (92 mg …
Silent new ischemic lesions after index stroke and the risk of future clinical recurrent stroke.
Kang DW, Han MK, Kim HJ, Sohn H, Kim BJ, Kwon SU, Kim JS, Warach S. Kang DW, et al. Neurology. 2016 Jan 19;86(3):277-85. doi: 10.1212/WNL.0000000000002289. Epub 2015 Dec 18. Neurology. 2016. PMID: 26683639 Free PMC article.
METHODS: In this prospective study, we analyzed data from patients presenting with acute ischemic stroke who underwent MRI <24 hours and 5 and 30 days after symptom onset. The presence of a SNIL at 5 (5D-SNIL) and 30 (30D-SNIL) days was determined on diffusion-weighted …
METHODS: In this prospective study, we analyzed data from patients presenting with acute ischemic stroke who underwent MRI <24 hours and …
Symptoms and Impaired Quality of Life After COVID-19 Hospitalization: Effect of Therapeutic Heparin in Non-ICU Patients in the Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 Acute Trial: Effect on 3-Month Symptoms and Quality of Life.
Greenstein YY, Hubel K, Froess J, Wisniewski SR, Venugopal V, Lai YH, Berger JS, Chang SY, Colovos C, Shah F, Kornblith LZ, Lawler PR, Gaddh M, Guerrero RM, Nkemdirim W, Lopes RD, Reynolds HR, Amigo JS, Wahid L, Zahra A, Goligher EC, Zarychanski R, Leifer E, Huang DT, Neal MD, Hochman JS, Cushman M, Gong MN. Greenstein YY, et al. Chest. 2024 Apr;165(4):785-799. doi: 10.1016/j.chest.2023.11.019. Epub 2023 Nov 17. Chest. 2024. PMID: 37979717 Clinical Trial.
Individual domains assessed by the EQ-5D-5L included mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. ...Among 410 patients, 148 (36.1%) reported moderate to severe impairment in one or more domains of the EQ-5D-5L. The presence of 90- …
Individual domains assessed by the EQ-5D-5L included mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. …
Cyanido-Bridged {LnIIIWV} Heterobinuclear Complexes: Synthesis and Magneto-Structural Study.
Alexandru MG, Visinescu D, Shova S, Lloret F, Julve M. Alexandru MG, et al. Inorg Chem. 2017 Oct 16;56(20):12594-12605. doi: 10.1021/acs.inorgchem.7b02050. Epub 2017 Sep 27. Inorg Chem. 2017. PMID: 28952727
This new series of {Ln(III)W(V)} heterobinuclear compounds provides more insights into the exchange magnetic interaction between 5d and 4f centers via the cyanide-bridge, for which scarce information is available to date....
This new series of {Ln(III)W(V)} heterobinuclear compounds provides more insights into the exchange magnetic interaction between 5d a …