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Variants of a putative baseplate wedge protein extend the host range of Pseudomonas phage K8.
Sun L, You J, Li D, Zhang Z, Qin X, Pang W, Li P, Han Q, Li Y, Huang Z, Zhang X, Gong M, Yang H. Sun L, et al. Microbiome. 2023 Jan 31;11(1):18. doi: 10.1186/s40168-022-01459-w. Microbiome. 2023. PMID: 36721246 Free PMC article.
BACKGROUND: Narrow host range is a major limitation for phage applications, but phages can evolve expanded host range through adaptations in the receptor-binding proteins. RESULTS: Here, we report that Pseudomonas phage K8 can evolve broader host range and hi …
BACKGROUND: Narrow host range is a major limitation for phage applications, but phages can evolve expanded host range through adaptations in …