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Comparative transcriptome analysis of Peromyscus leucopus and C3H mice infected with the Lyme disease pathogen.
Gaber AM, Mandric I, Nitirahardjo C, Piontkivska H, Hillhouse AE, Threadgill DW, Zelikovsky A, Rogovskyy AS. Gaber AM, et al. Front Cell Infect Microbiol. 2023 Apr 11;13:1115350. doi: 10.3389/fcimb.2023.1115350. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37113133 Free PMC article.
Lyme disease (LD), the most prevalent tick-borne disease of humans in the Northern Hemisphere, is caused by the spirochetal bacterium of Borreliella burgdorferi (Bb) sensu lato complex. In nature, Bb spirochetes are continuously transmitted between Ixodes ticks and …
Lyme disease (LD), the most prevalent tick-borne disease of humans in the Northern Hemisphere, is caused by the spirochetal bacterium of …
Lyme Disease Agent Reservoirs Peromyscus leucopus and P. maniculatus Have Natively Inactivated Genes for the High-Affinity Immunoglobulin Gamma Fc Receptor I (CD64).
Barbour AG, Duong JV, Long AD. Barbour AG, et al. Pathogens. 2023 Aug 18;12(8):1056. doi: 10.3390/pathogens12081056. Pathogens. 2023. PMID: 37624016 Free PMC article.
In the present study a prior observation of absent expression of the high-affinity Fc immunoglobulin gamma receptor I (FcgammaRI), or CD64, in P. leucopus was confirmed in an experimental infection with Borreliella burgdorferi, a Lyme disease agent. We demonstrate t …
In the present study a prior observation of absent expression of the high-affinity Fc immunoglobulin gamma receptor I (FcgammaRI), or CD64, …