PubMed

Dysfunctional Corin I555(P568) Allele Is Associated With Impaired Brain Natriuretic Peptide Processing and Adverse Outcomes in Blacks With Systolic Heart Failure: Results From the Genetic Risk Assessment in Heart Failure Substudy.

Rame JE, Tam SW, McNamara D, Worcel M, Sabolinski ML, Wu AH, Dries DL.

Circ Heart Fail. 2009 Nov 1;2(6):541-548. Epub 2009 Sep 28.PMID: 19919978 [PubMed - as supplied by publisher]Related articles

Inpp5f Is a Polyphosphoinositide Phosphatase That Regulates Cardiac Hypertrophic Responsiveness.

Zhu W, Trivedi CM, Zhou D, Yuan L, Lu MM, Epstein JA.

Circ Res. 2009 Oct 29. [Epub ahead of print]PMID: 19875726 [PubMed - as supplied by publisher]Related articles

N-Terminal Pro-Brain Natriuretic Peptide as a Biomarker for Hypertensive Disorders of Pregnancy.

Moghbeli N, Srinivas SK, Bastek J, Lu Y, Putt ME, Cappola TP, Elovitz MA.

Am J Perinatol. 2009 Oct 24. [Epub ahead of print]PMID: 19856261 [PubMed - as supplied by publisher]Related articles

Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers.

Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, Margulies KB, Madesh M, Eberwine JH, Epstein JA, Patel VV.

J Clin Invest. 2009 Nov;119(11):3420-36. doi: 10.1172/JCI39109. Epub 2009 Oct 12.PMID: 19855129 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardin is required for cardiomyocyte survival and maintenance of heart function.

Huang J, Min Lu M, Cheng L, Yuan LJ, Zhu X, Stout AL, Chen M, Li J, Parmacek MS.

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18734-9. Epub 2009 Oct 22.PMID: 19850880 [PubMed - in process]Related articles

Higher Serum Testosterone Concentration in Older Women is Associated with Insulin Resistance, Metabolic Syndrome, and Cardiovascular Disease.

Patel SM, Ratcliffe SJ, Reilly MP, Weinstein R, Bhasin S, Blackman MR, Cauley JA, Sutton-Tyrrell K, Robbins J, Fried LP, Cappola AR.

J Clin Endocrinol Metab. 2009 Oct 21. [Epub ahead of print]PMID: 19846742 [PubMed - as supplied by publisher]Related articles

Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.

McGillicuddy FC, Chiquoine EH, Hinkle CC, Kim RJ, Shah R, Roche HM, Smyth EM, Reilly MP.

J Biol Chem. 2009 Nov 13;284(46):31936-44. Epub 2009 Sep 23.PMID: 19776010 [PubMed - in process]Related articles

MicroRNA-modulated targeting of vascular smooth muscle cells.

Parmacek MS.

J Clin Invest. 2009 Sep;119(9):2526-8. doi: 10.1172/JCI40503. Epub 2009 Aug 17.PMID: 19690387 [PubMed - indexed for MEDLINE]Related articles

Inflammation induces fibrinogen nitration in experimental human endotoxemia.

Heffron SP, Parastatidis I, Cuchel M, Wolfe ML, Tadesse MG, Mohler ER 3rd, Ischiropoulos H, Rader DJ, Reilly MP.

Free Radic Biol Med. 2009 Oct 15;47(8):1140-6. Epub 2009 Jul 22.PMID: 19631267 [PubMed - in process]Related articles

Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure.

Ky B, Kimmel SE, Safa RN, Putt ME, Sweitzer NK, Fang JC, Sawyer DB, Cappola TP.

Circulation. 2009 Jul 28;120(4):310-7. Epub 2009 Jul 13.PMID: 19597049 [PubMed - indexed for MEDLINE]Related articles

Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction.

Xu J, Ismat FA, Wang T, Lu MM, Antonucci N, Epstein JA.

Circ Res. 2009 Jul 31;105(3):304-11. Epub 2009 Jul 2.PMID: 19574548 [PubMed - indexed for MEDLINE]Related articles

Cardiomyocyte renewal.

Parmacek MS, Epstein JA.

N Engl J Med. 2009 Jul 2;361(1):86-8. No abstract available. PMID: 19571289 [PubMed - indexed for MEDLINE]Related articles

Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation.

Griffon N, Jin W, Petty TJ, Millar J, Badellino KO, Saven JG, Marchadier DH, Kempner ES, Billheimer J, Glick JM, Rader DJ.

J Biol Chem. 2009 Aug 28;284(35):23322-30. Epub 2009 Jun 30.PMID: 19567873 [PubMed - indexed for MEDLINE]Related articles

Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development.

High FA, Jain R, Stoller JZ, Antonucci NB, Lu MM, Loomes KM, Kaestner KH, Pear WS, Epstein JA.

J Clin Invest. 2009 Jul;119(7):1986-96. doi: 10.1172/JCI38922. Epub 2009 Jun 8.PMID: 19509466 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein B but not LDL cholesterol is associated with coronary artery calcification in type 2 diabetic whites.

Martin SS, Qasim AN, Mehta NN, Wolfe M, Terembula K, Schwartz S, Iqbal N, Schutta M, Bagheri R, Reilly MP.

Diabetes. 2009 Aug;58(8):1887-92. Epub 2009 Jun 2.PMID: 19491209 [PubMed - indexed for MEDLINE]Related articlesFree article

Genomics, transcriptional profiling, and heart failure.

Margulies KB, Bednarik DP, Dries DL.

J Am Coll Cardiol. 2009 May 12;53(19):1752-9. Review.PMID: 19422981 [PubMed - indexed for MEDLINE]Related articles

Stem cells by the shore: Meeting summary of the 2008 MDI Stem Cell Symposium.

Epstein JA, Niemitz EL.

Epigenetics. 2009 Feb;4(2):125-6. Epub 2009 Mar 3. No abstract available. PMID: 19305143 [PubMed - indexed for MEDLINE]Related articles

Negative regulation of activated alpha-2 integrins during thrombopoiesis.

Zou Z, Schmaier AA, Cheng L, Mericko P, Dickeson SK, Stricker TP, Santoro SA, Kahn ML.

Blood. 2009 Jun 18;113(25):6428-39. Epub 2009 Mar 3.PMID: 19258597 [PubMed - indexed for MEDLINE]Related articles

Soluble p-selectin and the risk of primary graft dysfunction after lung transplantation.

Kawut SM, Okun J, Shimbo D, Lederer DJ, De Andrade J, Lama V, Shah A, Milstone A, Ware LB, Weinacker A, Demissie E, Christie JD; Lung Transplant Outcomes Group.

Chest. 2009 Jul;136(1):237-44. Epub 2009 Mar 2.PMID: 19255296 [PubMed - indexed for MEDLINE]Related articles

Inflammation impairs reverse cholesterol transport in vivo.

McGillicuddy FC, de la Llera Moya M, Hinkle CC, Joshi MR, Chiquoine EH, Billheimer JT, Rothblat GH, Reilly MP.

Circulation. 2009 Mar 3;119(8):1135-45. Epub 2009 Feb 16.PMID: 19221221 [PubMed - indexed for MEDLINE]Related articles

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.

Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Sweeney SM, Chen M, Guo L, Lu MM, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML.

Nat Med. 2009 Feb;15(2):169-76. Epub 2009 Jan 18. Erratum in: Nat Med. 2009 May;15(5):584. Sweeney, Shawn M [added]. PMID: 19151727 [PubMed - indexed for MEDLINE]Related articlesFree article

Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects.

Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA.

Dev Biol. 2009 Jan 1;325(1):82-93. Epub 2008 Oct 17.PMID: 18992737 [PubMed - indexed for MEDLINE]Related articles

Selective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitus.

Mehta NN, Sheetz M, Price K, Comiskey L, Amrutia S, Iqbal N, Mohler ER, Reilly MP.

Cardiovasc Drugs Ther. 2009 Feb;23(1):17-24. Epub 2008 Oct 24.PMID: 18949545 [PubMed - indexed for MEDLINE]Related articles

Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin.

Liu F, Levin MD, Petrenko NB, Lu MM, Wang T, Yuan LJ, Stout AL, Epstein JA, Patel VV.

J Mol Cell Cardiol. 2008 Dec;45(6):715-23. Epub 2008 Sep 16.PMID: 18926829 [PubMed - indexed for MEDLINE]Related articles

Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease.

Martin SS, Qasim A, Reilly MP.

J Am Coll Cardiol. 2008 Oct 7;52(15):1201-10. Review.PMID: 18926322 [PubMed - indexed for MEDLINE]Related articles

Apoptosis signal-regulating kinase 1 attenuates atrial natriuretic peptide secretion.

Shan X, Wang H, Margulies KB.

Biochemistry. 2008 Sep 23;47(38):10041-8. Epub 2008 Aug 30.PMID: 18759454 [PubMed - indexed for MEDLINE]Related articles

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.

Qasim AN, Metkus TS, Tadesse M, Lehrke M, Restine S, Wolfe ML, Hannenhalli S, Cappola T, Rader DJ, Reilly MP.

Clin Endocrinol (Oxf). 2009 May;70(5):698-705. Epub 2008 Aug 15.PMID: 18710472 [PubMed - indexed for MEDLINE]Related articles

Adipokines, insulin resistance, and coronary artery calcification.

Qasim A, Mehta NN, Tadesse MG, Wolfe ML, Rhodes T, Girman C, Reilly MP.

J Am Coll Cardiol. 2008 Jul 15;52(3):231-6.PMID: 18617073 [PubMed - indexed for MEDLINE]Related articles

Cardiac stem cells and progenitors: developmental biology and therapeutic challenges.

Parmacek MS.

Trans Am Clin Climatol Assoc. 2006;117:239-55; discussion 255-6. Review.PMID: 18528477 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of matrix metalloproteinase 9 and brain natriuretic peptide as clinical biomarkers in chronic heart failure.

Vorovich EE, Chuai S, Li M, Averna J, Marwin V, Wolfe D, Reilly MP, Cappola TP.

Am Heart J. 2008 Jun;155(6):992-7. Epub 2008 Feb 21.PMID: 18513509 [PubMed - indexed for MEDLINE]Related articlesFree article

Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates.

Sweeney SM, Orgel JP, Fertala A, McAuliffe JD, Turner KR, Di Lullo GA, Chen S, Antipova O, Perumal S, Ala-Kokko L, Forlino A, Cabral WA, Barnes AM, Marini JC, San Antonio JD.

J Biol Chem. 2008 Jul 25;283(30):21187-97. Epub 2008 May 15.PMID: 18487200 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice.

Wu M, Li J, Engleka KA, Zhou B, Lu MM, Plotkin JB, Epstein JA.

J Clin Invest. 2008 Jun;118(6):2076-87.PMID: 18483623 [PubMed - indexed for MEDLINE]Related articlesFree article

Atlantic City is passé--I'm betting on Chicago.

Epstein J.

J Clin Invest. 2008 Apr;118(4):1235-6.PMID: 18382734 [PubMed - indexed for MEDLINE]Related articlesFree article

A house with many rooms: how the heart got its chambers with foxn4.

Cohen ED, Morrisey EE.

Genes Dev. 2008 Mar 15;22(6):706-10. No abstract available. PMID: 18347088 [PubMed - indexed for MEDLINE]Related articlesFree article

Currying favor for the heart.

Epstein JA.

J Clin Invest. 2008 Mar;118(3):850-2. Erratum in: J Clin Invest. 2009 Jul;119(7):2113. PMID: 18292806 [PubMed - indexed for MEDLINE]Related articlesFree article

Translating molecular discoveries into new therapies for atherosclerosis.

Rader DJ, Daugherty A.

Nature. 2008 Feb 21;451(7181):904-13. Review.PMID: 18288179 [PubMed - indexed for MEDLINE]Related articles

Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal.

Cohen ED, Tian Y, Morrisey EE.

Development. 2008 Mar;135(5):789-98. Review.PMID: 18263841 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development.

High FA, Lu MM, Pear WS, Loomes KM, Kaestner KH, Epstein JA.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1955-9. Epub 2008 Feb 1.PMID: 18245384 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood is thicker than lymph.

Kahn ML.

J Clin Invest. 2008 Jan;118(1):23-6.PMID: 18097477 [PubMed - indexed for MEDLINE]Related articlesFree article

The multifaceted role of Notch in cardiac development and disease.

High FA, Epstein JA.

Nat Rev Genet. 2008 Jan;9(1):49-61. Review.PMID: 18071321 [PubMed - indexed for MEDLINE]Related articles

NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response.

Xu J, Ismat FA, Wang T, Yang J, Epstein JA.

Circulation. 2007 Nov 6;116(19):2148-56. Epub 2007 Oct 22.PMID: 17967772 [PubMed - indexed for MEDLINE]Related articlesFree article

Menin is required in cranial neural crest for palatogenesis and perinatal viability.

Engleka KA, Wu M, Zhang M, Antonucci NB, Epstein JA.

Dev Biol. 2007 Nov 15;311(2):524-37. Epub 2007 Sep 7.PMID: 17927973 [PubMed - indexed for MEDLINE]Related articles

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo.

Wang X, Collins HL, Ranalletta M, Fuki IV, Billheimer JT, Rothblat GH, Tall AR, Rader DJ.

J Clin Invest. 2007 Aug;117(8):2216-24.PMID: 17657311 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling.

Cohen ED, Wang Z, Lepore JJ, Lu MM, Taketo MM, Epstein DJ, Morrisey EE.

J Clin Invest. 2007 Jul;117(7):1794-804.PMID: 17607356 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular regulation of macrophage reverse cholesterol transport.

Wang X, Rader DJ.

Curr Opin Cardiol. 2007 Jul;22(4):368-72. Review.PMID: 17556891 [PubMed - indexed for MEDLINE]Related articles

Plasma cytokines, metabolic syndrome, and atherosclerosis in humans.

Reilly MP, Rohatgi A, McMahon K, Wolfe ML, Pinto SC, Rhodes T, Girman C, Rader DJ.

J Investig Med. 2007 Jan;55(1):26-35.PMID: 17441409 [PubMed - indexed for MEDLINE]Related articles

Foxp2 and Foxp1 cooperatively regulate lung and esophagus development.

Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE.

Development. 2007 May;134(10):1991-2000. Epub 2007 Apr 11.PMID: 17428829 [PubMed - indexed for MEDLINE]Related articlesFree article

Value of electrocardiographic and ankle-brachial index abnormalities for prediction of coronary atherosclerosis in asymptomatic subjects with type 2 diabetes mellitus.

Bagheri R, Schutta M, Cumaranatunge RG, Wolfe ML, Terembula K, Hoffman B, Schwartz S, Kimmel SE, Farouk S, Iqbal N, Reilly MP.

Am J Cardiol. 2007 Apr 1;99(7):951-5. Epub 2007 Feb 14.PMID: 17398190 [PubMed - indexed for MEDLINE]Related articles

Innate immunity modulates adipokines in humans.

Anderson PD, Mehta NN, Wolfe ML, Hinkle CC, Pruscino L, Comiskey LL, Tabita-Martinez J, Sellers KF, Rickels MR, Ahima RS, Reilly MP.

J Clin Endocrinol Metab. 2007 Jun;92(6):2272-9. Epub 2007 Mar 20.PMID: 17374708 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation.

Parmacek MS.

Circ Res. 2007 Mar 16;100(5):633-44. Review.PMID: 17363709 [PubMed - indexed for MEDLINE]Related articlesFree article

HDL proteomics: pot of gold or Pandora's box?

Reilly MP, Tall AR.

J Clin Invest. 2007 Mar;117(3):595-8.PMID: 17332889 [PubMed - indexed for MEDLINE]Related articlesFree article

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

High FA, Zhang M, Proweller A, Tu L, Parmacek MS, Pear WS, Epstein JA.

J Clin Invest. 2007 Feb;117(2):353-63.PMID: 17273555 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular regulation of HDL metabolism and function: implications for novel therapies.

Rader DJ.

J Clin Invest. 2006 Dec;116(12):3090-100. Review.PMID: 17143322 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired notch signaling promotes de novo squamous cell carcinoma formation.

Proweller A, Tu L, Lepore JJ, Cheng L, Lu MM, Seykora J, Millar SE, Pear WS, Parmacek MS.

Cancer Res. 2006 Aug 1;66(15):7438-44.PMID: 16885339 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of homeodomain-only protein in the cardiac conduction system.

Liu F, Ismat FA, Patel VV.

Trends Cardiovasc Med. 2006 Aug;16(6):193-8. Review.PMID: 16839862 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage reverse cholesterol transport: key to the regression of atherosclerosis?

Cuchel M, Rader DJ.

Circulation. 2006 May 30;113(21):2548-55. Review. No abstract available. PMID: 16735689 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein E and coronary disease: a puzzling paradox.

Reilly M, Rader DJ.

PLoS Med. 2006 Jun;3(6):e258. No abstract available. PMID: 16729847 [PubMed - indexed for MEDLINE]Related articlesFree article

High-density lipoprotein cholesterol therapies: the next frontier in lipid management.

Duffy D, Rader DJ.

J Cardiopulm Rehabil. 2006 Jan-Feb;26(1):1-8. Review.PMID: 16617219 [PubMed - indexed for MEDLINE]Related articles

GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis.

Lepore JJ, Mericko PA, Cheng L, Lu MM, Morrisey EE, Parmacek MS.

J Clin Invest. 2006 Apr;116(4):929-39. Epub 2006 Mar 23.PMID: 16557299 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of rosiglitazone on lipids, adipokines, and inflammatory markers in nondiabetic patients with low high-density lipoprotein cholesterol and metabolic syndrome.

Samaha FF, Szapary PO, Iqbal N, Williams MM, Bloedon LT, Kochar A, Wolfe ML, Rader DJ.

Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):624-30. Epub 2005 Dec 15.PMID: 16357312 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo.

Zhang Y, Da Silva JR, Reilly M, Billheimer JT, Rothblat GH, Rader DJ.

J Clin Invest. 2005 Oct;115(10):2870-4.PMID: 16200214 [PubMed - indexed for MEDLINE]Related articlesFree article

Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease.

Epstein JA, Parmacek MS.

Circulation. 2005 Jul 26;112(4):592-7. Review. No abstract available. PMID: 16043659 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development.

Li J, Zhu X, Chen M, Cheng L, Zhou D, Lu MM, Du K, Epstein JA, Parmacek MS.

Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8916-21. Epub 2005 Jun 10.PMID: 15951419 [PubMed - indexed for MEDLINE]Related articlesFree article