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Sequence diversity between class I MHC loci of African native and introduced Bos taurus cattle in Theileria parva endemic regions: in silico peptide binding prediction identifies distinct functional clusters.
Obara I, Nielsen M, Jeschek M, Nijhof A, Mazzoni CJ, Svitek N, Steinaa L, Awino E, Olds C, Jabbar A, Clausen PH, Bishop RP. Obara I, et al. Immunogenetics. 2016 May;68(5):339-52. doi: 10.1007/s00251-016-0902-5. Epub 2016 Feb 6. Immunogenetics. 2016. PMID: 26852329
There is strong evidence that the immunity induced by live vaccination for control of the protozoan parasite Theileria parva is mediated by class I MHC-restricted CD8(+) T cells directed against the schizont stage of the parasite that infects bovine lymphocytes. The …
There is strong evidence that the immunity induced by live vaccination for control of the protozoan parasite Theileria parva i …
In vivo comparison of susceptibility between Bos indicus and Bos taurus cattle types to Theileria parva infection.
Ndungu SG, Brown CG, Dolan TT. Ndungu SG, et al. Onderstepoort J Vet Res. 2005 Mar;72(1):13-22. Onderstepoort J Vet Res. 2005. PMID: 15991702
The objective of this study was to determine whether Bos taurus cattle differ form Bos indicus in their susceptibility to infection with the Muguga stabilate of Theileria parva and in their resistance to the resultant disease. ...
The objective of this study was to determine whether Bos taurus cattle differ form Bos indicus in their susceptibility to infe …
Antigen gene and variable number tandem repeat (VNTR) diversity in Theileria parva parasites from Ankole cattle in south-western Uganda: Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci.
Nanteza A, Obara I, Kasaija P, Mwega E, Kabi F, Salih DA, Njahira M, Njuguna J, Odongo D, Bishop RP, Skilton RA, Ahmed J, Clausen PH, Lubega GW. Nanteza A, et al. Transbound Emerg Dis. 2020 Mar;67 Suppl 1:99-107. doi: 10.1111/tbed.13311. Transbound Emerg Dis. 2020. PMID: 32174038
Theileria parva is a tick-transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a frequently fatal disease of cattle in eastern, central and southern Africa. ...This study investigated the …
Theileria parva is a tick-transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buff …
The response of Bos taurus and Bos indicus cattle types to inoculation of lymphoblastoid cell lines infected with Theileria parva schizonts.
Dolan TT, Njuguna LN, Stagg DA. Dolan TT, et al. Tropenmed Parasitol. 1982 Mar;33(1):57-62. Tropenmed Parasitol. 1982. PMID: 6808728
In a preliminary experiment eight Bos indicus type cattle were inoculated with 10(9) cells of a Bos taurus lymphoblastoid cell line infected with Theileria parva schizonts. ...Two Bos taurus type cattle receiving Bos taurus …
In a preliminary experiment eight Bos indicus type cattle were inoculated with 10(9) cells of a Bos taurus lymphoblastoid cell …
Deciphering the kinome of Theileria annulata for identification of drug targets and anti-theilerial drug.
Kar PP, Araveti PB, Srivastava A. Kar PP, et al. Ticks Tick Borne Dis. 2022 Nov;13(6):102049. doi: 10.1016/j.ttbdis.2022.102049. Epub 2022 Sep 29. Ticks Tick Borne Dis. 2022. PMID: 36215767
Three protein kinases, TA16570, TA09820, and TA07000, had <40% identity with Bos taurus and >40% identity with the previously identified potential drug targets present in the Therapeutic Target Database (TTD). ...Only Dabrafenib, out of these 5 drugs, could bi …
Three protein kinases, TA16570, TA09820, and TA07000, had <40% identity with Bos taurus and >40% identity with the previ …
A Theileria parva isolate of low virulence infects a subpopulation of lymphocytes.
Tindih HS, Geysen D, Goddeeris BM, Awino E, Dobbelaere DA, Naessens J. Tindih HS, et al. Infect Immun. 2012 Mar;80(3):1267-73. doi: 10.1128/IAI.05085-11. Epub 2011 Dec 27. Infect Immun. 2012. PMID: 22202119 Free PMC article.
Theileria parva is a tick-transmitted protozoan parasite that infects and transforms bovine lymphocytes. We have previously shown that Theileria parva Chitongo is an isolate with a lower virulence than that of T. parva Muguga. ...
Theileria parva is a tick-transmitted protozoan parasite that infects and transforms bovine lymphocytes. We have previously sh …
CD4 T Cell Responses to Theileria parva in Immune Cattle Recognize a Diverse Set of Parasite Antigens Presented on the Surface of Infected Lymphoblasts.
Morrison WI, Aguado A, Sheldrake TA, Palmateer NC, Ifeonu OO, Tretina K, Parsons K, Fenoy E, Connelley T, Nielsen M, Silva JC. Morrison WI, et al. J Immunol. 2021 Oct 15;207(8):1965-1977. doi: 10.4049/jimmunol.2100331. Epub 2021 Sep 10. J Immunol. 2021. PMID: 34507950
Parasite-specific CD8 T cell responses play a key role in mediating immunity against Theileria parva in cattle (Bos taurus), and there is evidence that efficient induction of these responses requires CD4 T cell responses. ...
Parasite-specific CD8 T cell responses play a key role in mediating immunity against Theileria parva in cattle (Bos …
Synergistic Effect of Two Nanotechnologies Enhances the Protective Capacity of the Theileria parva Sporozoite p67C Antigen in Cattle.
Lacasta A, Mody KT, De Goeyse I, Yu C, Zhang J, Nyagwange J, Mwalimu S, Awino E, Saya R, Njoroge T, Muriuki R, Ndiwa N, Poole EJ, Zhang B, Cavallaro A, Mahony TJ, Steinaa L, Mitter N, Nene V. Lacasta A, et al. J Immunol. 2021 Feb 15;206(4):686-699. doi: 10.4049/jimmunol.2000442. Epub 2021 Jan 8. J Immunol. 2021. PMID: 33419770 Free PMC article.
East Coast fever (ECF), caused by Theileria parva, is the most important tick-borne disease of cattle in sub-Saharan Africa. ...Individually, HBcAg-p67C (chimeric hepatitis B core Ag virus-like particles displaying p67C) and silica vesicle (SV)-p67C (s-p67C adsorbed …
East Coast fever (ECF), caused by Theileria parva, is the most important tick-borne disease of cattle in sub-Saharan Africa. . …
Relationship between burden of infection in ungulate populations and wildlife/livestock interfaces.
Caron A, Miguel E, Gomo C, Makaya P, Pfukenyi DM, Foggin C, Hove T, de Garine-Wichatitsky M. Caron A, et al. Epidemiol Infect. 2013 Jul;141(7):1522-35. doi: 10.1017/S0950268813000204. Epub 2013 Feb 26. Epidemiol Infect. 2013. PMID: 23442901 Free PMC article.
Here, we assessed the infection burdens of sympatric domestic cattle (Bos taurus/Bos indicus) and African buffalo (Syncerus caffer) at an unfenced interface and compared the infection burdens of cattle populations at different wildlife/livestock interfaces in the Gr …
Here, we assessed the infection burdens of sympatric domestic cattle (Bos taurus/Bos indicus) and African buffalo (Syncerus ca …
Identification of a target population for immunisation against East Coast fever in coastal Kenya.
Maloo SH, Ngumi P, Mbogo S, Williamson S, Thorpe W, Rowlands GJ, Perry BD. Maloo SH, et al. Prev Vet Med. 2001 Nov 2;52(1):31-41. doi: 10.1016/s0167-5877(01)00236-7. Prev Vet Med. 2001. PMID: 11566376 Clinical Trial.
Firstly, a sentinel-calf study was used to determine the age window for ECF immunisation by determining ages at clinical detection of infection with Theileria parva. Six groups of five naive cross-bred (Bos taurus/Bos indicus) male calves, introduced a …
Firstly, a sentinel-calf study was used to determine the age window for ECF immunisation by determining ages at clinical detection of infect …
14 results