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Items: 1 to 20 of 545

1.

Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life.

Davies ER, Kelly JF, Howarth PH, Wilson DI, Holgate ST, Davies DE, Whitsett JA, Haitchi HM.

JCI Insight. 2016 Jul 21;1(11). pii: e87632.

2.

INFLAMMATION. Modulating pulmonary inflammation.

Whitsett JA, Morrisey EE.

Science. 2016 Feb 12;351(6274):662-3. doi: 10.1126/science.aaf1429. No abstract available.

PMID:
26912844
3.

β-catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis.

Ustiyan V, Zhang Y, Perl AK, Whitsett JA, Kalin TV, Kalinichenko VV.

Dev Dyn. 2016 May;245(5):590-604. doi: 10.1002/dvdy.24393. Epub 2016 Mar 8.

PMID:
26869074
4.

SINCERA: A Pipeline for Single-Cell RNA-Seq Profiling Analysis.

Guo M, Wang H, Potter SS, Whitsett JA, Xu Y.

PLoS Comput Biol. 2015 Nov 24;11(11):e1004575. doi: 10.1371/journal.pcbi.1004575. eCollection 2015 Nov.

5.

Systems biology evaluation of cell-free amniotic fluid transcriptome of term and preterm infants to detect fetal maturity.

Kamath-Rayne BD, Du Y, Hughes M, Wagner EA, Muglia LJ, DeFranco EA, Whitsett JA, Salomonis N, Xu Y.

BMC Med Genomics. 2015 Oct 22;8:67. doi: 10.1186/s12920-015-0138-5.

6.

A favourable prognostic marker for EGFR mutant non-small cell lung cancer: immunohistochemical analysis of MUC5B.

Wakata K, Tsuchiya T, Tomoshige K, Takagi K, Yamasaki N, Matsumoto K, Miyazaki T, Nanashima A, Whitsett JA, Maeda Y, Nagayasu T.

BMJ Open. 2015 Jul 29;5(7):e008366. doi: 10.1136/bmjopen-2015-008366.

7.

'LungGENS': a web-based tool for mapping single-cell gene expression in the developing lung.

Du Y, Guo M, Whitsett JA, Xu Y.

Thorax. 2015 Nov;70(11):1092-4. doi: 10.1136/thoraxjnl-2015-207035. Epub 2015 Jun 30. Review.

8.

Alveolar development and disease.

Whitsett JA, Weaver TE.

Am J Respir Cell Mol Biol. 2015 Jul;53(1):1-7. doi: 10.1165/rcmb.2015-0128PS. Review.

9.

Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation.

Rajavelu P, Chen G, Xu Y, Kitzmiller JA, Korfhagen TR, Whitsett JA.

J Clin Invest. 2015 May;125(5):2021-31. doi: 10.1172/JCI79422. Epub 2015 Apr 13.

10.

A novel PI3K inhibitor iMDK suppresses non-small cell lung Cancer cooperatively with A MEK inhibitor.

Ishida N, Fukazawa T, Maeda Y, Yamatsuji T, Kato K, Matsumoto K, Shimo T, Takigawa N, Whitsett JA, Naomoto Y.

Exp Cell Res. 2015 Jul 15;335(2):197-206. doi: 10.1016/j.yexcr.2015.03.019. Epub 2015 Apr 1.

11.

Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.

Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL.

Development. 2015 Apr 1;142(7):1315-24. doi: 10.1242/dev.115808.

12.

Diseases of pulmonary surfactant homeostasis.

Whitsett JA, Wert SE, Weaver TE.

Annu Rev Pathol. 2015;10:371-93. doi: 10.1146/annurev-pathol-012513-104644. Review.

13.

Respiratory epithelial cells orchestrate pulmonary innate immunity.

Whitsett JA, Alenghat T.

Nat Immunol. 2015 Jan;16(1):27-35. doi: 10.1038/ni.3045. Review.

14.

Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung.

Lange AW, Sridharan A, Xu Y, Stripp BR, Perl AK, Whitsett JA.

J Mol Cell Biol. 2015 Feb;7(1):35-47. doi: 10.1093/jmcb/mju046. Epub 2014 Dec 5.

15.

TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium.

McCauley HA, Liu CY, Attia AC, Wikenheiser-Brokamp KA, Zhang Y, Whitsett JA, Guasch G.

Development. 2014 Dec;141(23):4628-39. doi: 10.1242/dev.117804. Epub 2014 Nov 5.

16.

Differential roles of STAT3 in the initiation and growth of lung cancer.

Zhou J, Qu Z, Yan S, Sun F, Whitsett JA, Shapiro SD, Xiao G.

Oncogene. 2015 Jul;34(29):3804-14. doi: 10.1038/onc.2014.318. Epub 2014 Oct 6.

17.

Foxm1 regulates resolution of hyperoxic lung injury in newborns.

Xia H, Ren X, Bolte CS, Ustiyan V, Zhang Y, Shah TA, Kalin TV, Whitsett JA, Kalinichenko VV.

Am J Respir Cell Mol Biol. 2015 May;52(5):611-21. doi: 10.1165/rcmb.2014-0091OC.

18.

SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene.

Cheng XH, Black M, Ustiyan V, Le T, Fulford L, Sridharan A, Medvedovic M, Kalinichenko VV, Whitsett JA, Kalin TV.

PLoS Genet. 2014 Sep 25;10(9):e1004656. doi: 10.1371/journal.pgen.1004656. eCollection 2014 Sep.

19.

Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function.

Hogan BL, Barkauskas CE, Chapman HA, Epstein JA, Jain R, Hsia CC, Niklason L, Calle E, Le A, Randell SH, Rock J, Snitow M, Krummel M, Stripp BR, Vu T, White ES, Whitsett JA, Morrisey EE.

Cell Stem Cell. 2014 Aug 7;15(2):123-38. doi: 10.1016/j.stem.2014.07.012. Review.

20.

The molecular era of surfactant biology.

Whitsett JA.

Neonatology. 2014;105(4):337-43. doi: 10.1159/000360649. Epub 2014 May 30. Review.

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