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Results: 20


Evaluation of the agonist PET radioligand [¹¹C]GR103545 to image kappa opioid receptor in humans: kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242.

Naganawa M, Jacobsen LK, Zheng MQ, Lin SF, Banerjee A, Byon W, Weinzimmer D, Tomasi G, Nabulsi N, Grimwood S, Badura LL, Carson RE, McCarthy TJ, Huang Y.

Neuroimage. 2014 Oct 1;99:69-79. doi: 10.1016/j.neuroimage.2014.05.033. Epub 2014 May 17.


Phosphodiesterase 10A PET radioligand development program: from pig to human.

Plisson C, Weinzimmer D, Jakobsen S, Natesan S, Salinas C, Lin SF, Labaree D, Zheng MQ, Nabulsi N, Marques TR, Kapur S, Kawanishi E, Saijo T, Gunn RN, Carson RE, Rabiner EA.

J Nucl Med. 2014 Apr;55(4):595-601. doi: 10.2967/jnumed.113.131409. Epub 2014 Mar 10.


Imaging nicotine- and amphetamine-induced dopamine release in rhesus monkeys with [(11)C]PHNO vs [(11)C]raclopride PET.

Gallezot JD, Kloczynski T, Weinzimmer D, Labaree D, Zheng MQ, Lim K, Rabiner EA, Ridler K, Pittman B, Huang Y, Carson RE, Morris ED, Cosgrove KP.

Neuropsychopharmacology. 2014 Mar;39(4):866-74. doi: 10.1038/npp.2013.286. Epub 2013 Oct 15.


Clinical doses of atomoxetine significantly occupy both norepinephrine and serotonin transports: Implications on treatment of depression and ADHD.

Ding YS, Naganawa M, Gallezot JD, Nabulsi N, Lin SF, Ropchan J, Weinzimmer D, McCarthy TJ, Carson RE, Huang Y, Laruelle M.

Neuroimage. 2014 Feb 1;86:164-71. doi: 10.1016/j.neuroimage.2013.08.001. Epub 2013 Aug 9.


Determination of in vivo Bmax and Kd for 11C-GR103545, an agonist PET tracer for κ-opioid receptors: a study in nonhuman primates.

Tomasi G, Nabulsi N, Zheng MQ, Weinzimmer D, Ropchan J, Blumberg L, Brown-Proctor C, Ding YS, Carson RE, Huang Y.

J Nucl Med. 2013 Apr;54(4):600-8. doi: 10.2967/jnumed.112.112672. Epub 2013 Feb 19.


Kinetic analysis of drug-target interactions with PET for characterization of pharmacological hysteresis.

Salinas C, Weinzimmer D, Searle G, Labaree D, Ropchan J, Huang Y, Rabiner EA, Carson RE, Gunn RN.

J Cereb Blood Flow Metab. 2013 May;33(5):700-7. doi: 10.1038/jcbfm.2012.208. Epub 2013 Feb 6.


Optimization of PET-MR registrations for nonhuman primates using mutual information measures: a Multi-Transform Method (MTM).

Sandiego CM, Weinzimmer D, Carson RE.

Neuroimage. 2013 Jan 1;64:571-81. doi: 10.1016/j.neuroimage.2012.08.051. Epub 2012 Aug 25.


Ex vivo and in vivo evaluation of the norepinephrine transporter ligand [11C]MRB for brown adipose tissue imaging.

Lin SF, Fan X, Yeckel CW, Weinzimmer D, Mulnix T, Gallezot JD, Carson RE, Sherwin RS, Ding YS.

Nucl Med Biol. 2012 Oct;39(7):1081-6. doi: 10.1016/j.nucmedbio.2012.04.005. Epub 2012 May 16.


Glucose metabolism in the insula and cingulate is affected by systemic inflammation in humans.

Hannestad J, Subramanyam K, Dellagioia N, Planeta-Wilson B, Weinzimmer D, Pittman B, Carson RE.

J Nucl Med. 2012 Apr;53(4):601-7. doi: 10.2967/jnumed.111.097014. Epub 2012 Mar 13.


Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo.

Gallezot JD, Beaver JD, Gunn RN, Nabulsi N, Weinzimmer D, Singhal T, Slifstein M, Fowles K, Ding YS, Huang Y, Laruelle M, Carson RE, Rabiner EA.

Synapse. 2012 Jun;66(6):489-500. doi: 10.1002/syn.21535. Epub 2012 Feb 24.


Recovery from chronic spinal cord contusion after Nogo receptor intervention.

Wang X, Duffy P, McGee AW, Hasan O, Gould G, Tu N, Harel NY, Huang Y, Carson RE, Weinzimmer D, Ropchan J, Benowitz LI, Cafferty WB, Strittmatter SM.

Ann Neurol. 2011 Nov;70(5):805-21. doi: 10.1002/ana.22527.


Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A.

Plisson C, Salinas C, Weinzimmer D, Labaree D, Lin SF, Ding YS, Jakobsen S, Smith PW, Eiji K, Carson RE, Gunn RN, Rabiner EA.

Nucl Med Biol. 2011 Aug;38(6):875-84. doi: 10.1016/j.nucmedbio.2011.02.005. Epub 2011 Mar 30.


Assessing the sensitivity of [¹¹C]p943, a novel 5-HT1B radioligand, to endogenous serotonin release.

Cosgrove KP, Kloczynski T, Nabulsi N, Weinzimmer D, Lin SF, Staley JK, Bhagwagar Z, Carson RE.

Synapse. 2011 Oct;65(10):1113-7. doi: 10.1002/syn.20942. Epub 2011 May 3.


Evaluation of [(11)C]MRB for assessment of occupancy of norepinephrine transporters: Studies with atomoxetine in non-human primates.

Gallezot JD, Weinzimmer D, Nabulsi N, Lin SF, Fowles K, Sandiego C, McCarthy TJ, Maguire RP, Carson RE, Ding YS.

Neuroimage. 2011 May 1;56(1):268-79. doi: 10.1016/j.neuroimage.2010.09.040. Epub 2010 Sep 30.


Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.

Singhal T, Ding YS, Weinzimmer D, Normandin MD, Labaree D, Ropchan J, Nabulsi N, Lin SF, Skaddan MB, Soeller WC, Huang Y, Carson RE, Treadway JL, Cline GW.

Mol Imaging Biol. 2011 Oct;13(5):973-84. doi: 10.1007/s11307-010-0406-x. Epub 2010 Sep 8.


High-resolution imaging of brain 5-HT 1B receptors in the rhesus monkey using [11C]P943.

Nabulsi N, Huang Y, Weinzimmer D, Ropchan J, Frost JJ, McCarthy T, Carson RE, Ding YS.

Nucl Med Biol. 2010 Feb;37(2):205-14. doi: 10.1016/j.nucmedbio.2009.10.007. Epub 2009 Dec 1.


Arterial transit time effects in pulsed arterial spin labeling CBF mapping: insight from a PET and MR study in normal human subjects.

Qiu M, Paul Maguire R, Arora J, Planeta-Wilson B, Weinzimmer D, Wang J, Wang Y, Kim H, Rajeevan N, Huang Y, Carson RE, Constable RT.

Magn Reson Med. 2010 Feb;63(2):374-84. doi: 10.1002/mrm.22218.


Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies.

Bennacef I, Salinas CA, Bonasera TA, Gunn RN, Audrain H, Jakobsen S, Nabulsi N, Weinzimmer D, Carson RE, Huang Y, Holmes I, Micheli F, Heidbreder C, Gentile G, Rossi T, Laruelle M.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5056-9. doi: 10.1016/j.bmcl.2009.07.055. Epub 2009 Jul 25.


123I-5-IA-85380 SPECT measurement of nicotinic acetylcholine receptors in human brain by the constant infusion paradigm: feasibility and reproducibility.

Staley JK, van Dyck CH, Weinzimmer D, Brenner E, Baldwin RM, Tamagnan GD, Riccardi P, Mitsis E, Seibyl JP.

J Nucl Med. 2005 Sep;46(9):1466-72.


Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking.

Staley JK, Gottschalk C, Petrakis IL, Gueorguieva R, O'Malley S, Baldwin R, Jatlow P, Verhoeff NP, Perry E, Weinzimmer D, Frohlich E, Ruff E, van Dyck CH, Seibyl JP, Innis RB, Krystal JH.

Arch Gen Psychiatry. 2005 Aug;62(8):877-88.

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