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Results: 1 to 20 of 88

1.

Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing.

Lipka DB, Wang Q, Cabezas-Wallscheid N, Klimmeck D, Weichenhan D, Herrmann C, Lier A, Brocks D, von Paleske L, Renders S, Wünsche P, Zeisberger P, Gu L, Haas S, Essers MA, Brors B, Eils R, Trumpp A, Milsom MD, Plass C.

Cell Cycle. 2014 Nov 15;13(22):3476-3487.

PMID:
25483069
[PubMed - as supplied by publisher]
2.

Transcriptome-wide Profiling and Posttranscriptional Analysis of Hematopoietic Stem/Progenitor Cell Differentiation toward Myeloid Commitment.

Klimmeck D, Cabezas-Wallscheid N, Reyes A, von Paleske L, Renders S, Hansson J, Krijgsveld J, Huber W, Trumpp A.

Stem Cell Reports. 2014 Nov 11;3(5):858-75. doi: 10.1016/j.stemcr.2014.08.012. Epub 2014 Sep 25.

PMID:
25418729
[PubMed - in process]
Free PMC Article
3.

Co-expression of MET and CD47 is a novel prognosticator for survival of luminal breast cancer patients.

Baccelli I, Stenzinger A, Vogel V, Pfitzner BM, Klein C, Wallwiener M, Scharpff M, Saini M, Holland-Letz T, Sinn HP, Schneeweiss A, Denkert C, Weichert W, Trumpp A.

Oncotarget. 2014 Sep 30;5(18):8147-60.

PMID:
25230070
[PubMed - in process]
Free PMC Article
4.

Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA Methylome analysis.

Cabezas-Wallscheid N, Klimmeck D, Hansson J, Lipka DB, Reyes A, Wang Q, Weichenhan D, Lier A, von Paleske L, Renders S, Wünsche P, Zeisberger P, Brocks D, Gu L, Herrmann C, Haas S, Essers MA, Brors B, Eils R, Huber W, Milsom MD, Plass C, Krijgsveld J, Trumpp A.

Cell Stem Cell. 2014 Oct 2;15(4):507-22. doi: 10.1016/j.stem.2014.07.005. Epub 2014 Aug 21.

PMID:
25158935
[PubMed - in process]
5.

Serial enumeration of circulating tumor cells predicts treatment response and prognosis in metastatic breast cancer: a prospective study in 393 patients.

Wallwiener M, Riethdorf S, Hartkopf AD, Modugno C, Nees J, Madhavan D, Sprick MR, Schott S, Domschke C, Baccelli I, Schönfisch B, Burwinkel B, Marmé F, Heil J, Sohn C, Pantel K, Trumpp A, Schneeweiss A.

BMC Cancer. 2014 Jul 11;14:512. doi: 10.1186/1471-2407-14-512.

PMID:
25015676
[PubMed - in process]
Free PMC Article
6.

Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis.

Madhavan D, Wallwiener M, Bents K, Zucknick M, Nees J, Schott S, Cuk K, Riethdorf S, Trumpp A, Pantel K, Sohn C, Schneeweiss A, Surowy H, Burwinkel B.

Breast Cancer Res Treat. 2014 Jul;146(1):163-74. doi: 10.1007/s10549-014-2946-2. Epub 2014 May 17.

PMID:
24838941
[PubMed - in process]
7.

Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence.

Ehninger A, Boch T, Medyouf H, Müdder K, Orend G, Trumpp A.

Blood. 2014 Jun 26;123(26):4054-63. doi: 10.1182/blood-2013-10-533711. Epub 2014 May 15.

PMID:
24833352
[PubMed - indexed for MEDLINE]
8.

Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response.

Ehninger A, Boch T, Uckelmann H, Essers MA, Müdder K, Sleckman BP, Trumpp A.

Blood. 2014 Jun 19;123(25):3909-13. doi: 10.1182/blood-2013-10-531038. Epub 2014 May 2.

PMID:
24795346
[PubMed - indexed for MEDLINE]
9.

Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.

Carnevalli LS, Scognamiglio R, Cabezas-Wallscheid N, Rahmig S, Laurenti E, Masuda K, Jöckel L, Kuck A, Sujer S, Polykratis A, Erlacher M, Pasparakis M, Essers MA, Trumpp A.

J Exp Med. 2014 May 5;211(5):769-79. doi: 10.1084/jem.20131072. Epub 2014 Apr 21.

PMID:
24752302
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit.

Medyouf H, Mossner M, Jann JC, Nolte F, Raffel S, Herrmann C, Lier A, Eisen C, Nowak V, Zens B, Müdder K, Klein C, Obländer J, Fey S, Vogler J, Fabarius A, Riedl E, Roehl H, Kohlmann A, Staller M, Haferlach C, Müller N, John T, Platzbecker U, Metzgeroth G, Hofmann WK, Trumpp A, Nowak D.

Cell Stem Cell. 2014 Jun 5;14(6):824-37. doi: 10.1016/j.stem.2014.02.014. Epub 2014 Apr 3.

PMID:
24704494
[PubMed - in process]
11.

Expression and prognostic significance of cancer stem cell markers CD24 and CD44 in urothelial bladder cancer xenografts and patients undergoing radical cystectomy.

Hofner T, Macher-Goeppinger S, Klein C, Schillert A, Eisen C, Wagner S, Rigo-Watermeier T, Baccelli I, Vogel V, Trumpp A, Sprick MR.

Urol Oncol. 2014 Jul;32(5):678-86. doi: 10.1016/j.urolonc.2014.01.001. Epub 2014 Mar 12.

PMID:
24631171
[PubMed - in process]
12.

The impact of type 2 diabetes on the outcome of localized renal cell carcinoma.

Höfner T, Zeier M, Hatiboglu G, Eisen C, Schönberg G, Hadaschik B, Teber D, Duensing S, Trumpp A, Hohenfellner M, Pahernik S.

World J Urol. 2014 Dec;32(6):1537-42. doi: 10.1007/s00345-013-1231-z. Epub 2013 Dec 27.

PMID:
24370691
[PubMed - in process]
13.

Hypermutation of the inactive X chromosome is a frequent event in cancer.

Jäger N, Schlesner M, Jones DT, Raffel S, Mallm JP, Junge KM, Weichenhan D, Bauer T, Ishaque N, Kool M, Northcott PA, Korshunov A, Drews RM, Koster J, Versteeg R, Richter J, Hummel M, Mack SC, Taylor MD, Witt H, Swartman B, Schulte-Bockholt D, Sultan M, Yaspo ML, Lehrach H, Hutter B, Brors B, Wolf S, Plass C, Siebert R, Trumpp A, Rippe K, Lehmann I, Lichter P, Pfister SM, Eils R.

Cell. 2013 Oct 24;155(3):567-81. doi: 10.1016/j.cell.2013.09.042. Epub 2013 Oct 17.

PMID:
24139898
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization.

Tesio M, Oser GM, Baccelli I, Blanco-Bose W, Wu H, Göthert JR, Kogan SC, Trumpp A.

J Exp Med. 2013 Oct 21;210(11):2337-49. doi: 10.1084/jem.20122768. Epub 2013 Oct 14.

PMID:
24127490
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.

Cabezas-Wallscheid N, Eichwald V, de Graaf J, Löwer M, Lehr HA, Kreft A, Eshkind L, Hildebrandt A, Abassi Y, Heck R, Dehof AK, Ohngemach S, Sprengel R, Wörtge S, Schmitt S, Lotz J, Meyer C, Kindler T, Zhang DE, Kaina B, Castle JC, Trumpp A, Sahin U, Bockamp E.

EMBO Mol Med. 2013 Dec;5(12):1804-20. doi: 10.1002/emmm.201302661. Epub 2013 Oct 4.

PMID:
24124051
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Development and characteristics of preclinical experimental models for the research of rare neuroendocrine bladder cancer.

Hofner T, Macher-Goeppinger S, Klein C, Rigo-Watermeier T, Eisen C, Pahernik S, Hohenfellner M, Trumpp A, Sprick MR.

J Urol. 2013 Dec;190(6):2263-70. doi: 10.1016/j.juro.2013.06.053. Epub 2013 Jun 29.

PMID:
23820058
[PubMed - indexed for MEDLINE]
17.

Quaternizing diboranes(4): highly divergent outcomes and an inorganic Wagner-Meerwein rearrangement.

Braunschweig H, Damme A, Dewhurst RD, Kramer T, Kupfer T, Radacki K, Siedler E, Trumpp A, Wagner K, Werner C.

J Am Chem Soc. 2013 Jun 12;135(23):8702-7. doi: 10.1021/ja403037k. Epub 2013 Jun 3.

PMID:
23687934
[PubMed - indexed for MEDLINE]
18.

Label retaining cells in cancer--the dormant root of evil?

Schillert A, Trumpp A, Sprick MR.

Cancer Lett. 2013 Nov 28;341(1):73-9. doi: 10.1016/j.canlet.2013.04.019. Epub 2013 Apr 23. Review.

PMID:
23624300
[PubMed - indexed for MEDLINE]
19.

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay.

Baccelli I, Schneeweiss A, Riethdorf S, Stenzinger A, Schillert A, Vogel V, Klein C, Saini M, Bäuerle T, Wallwiener M, Holland-Letz T, Höfner T, Sprick M, Scharpff M, Marmé F, Sinn HP, Pantel K, Weichert W, Trumpp A.

Nat Biotechnol. 2013 Jun;31(6):539-44. doi: 10.1038/nbt.2576. Epub 2013 Apr 21.

PMID:
23609047
[PubMed - indexed for MEDLINE]
20.

The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer.

Wallwiener M, Hartkopf AD, Baccelli I, Riethdorf S, Schott S, Pantel K, Marmé F, Sohn C, Trumpp A, Rack B, Aktas B, Solomayer EF, Müller V, Janni W, Schneeweiss A, Fehm TN.

Breast Cancer Res Treat. 2013 Jan;137(2):503-10. doi: 10.1007/s10549-012-2382-0. Epub 2012 Dec 28.

PMID:
23271327
[PubMed - indexed for MEDLINE]

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