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Results: 1 to 20 of 31

1.

Mitochondrial quality, dynamics and functional capacity in Parkinson's disease cybrid cell lines selected for Lewy body expression.

Cronin-Furman EN, Borland MK, Bergquist KE, Bennett JP Jr, Trimmer PA.

Mol Neurodegener. 2013 Jan 26;8:6. doi: 10.1186/1750-1326-8-6.

PMID:
23351342
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy.

Trimmer PA, Schwartz KM, Borland MK, De Taboada L, Streeter J, Oron U.

Mol Neurodegener. 2009 Jun 17;4:26. doi: 10.1186/1750-1326-4-26.

PMID:
19534794
[PubMed]
Free PMC Article
3.

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP Jr.

Hum Gene Ther. 2009 Aug;20(8):897-907. doi: 10.1089/hum.2009.023.

PMID:
19374590
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The cybrid model of sporadic Parkinson's disease.

Trimmer PA, Bennett JP Jr.

Exp Neurol. 2009 Aug;218(2):320-5. doi: 10.1016/j.expneurol.2009.03.016. Epub 2009 Mar 26. Review.

PMID:
19328199
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells.

Borland MK, Trimmer PA, Rubinstein JD, Keeney PM, Mohanakumar K, Liu L, Bennett JP Jr.

Mol Neurodegener. 2008 Dec 29;3:21. doi: 10.1186/1750-1326-3-21.

PMID:
19114014
[PubMed]
Free PMC Article
6.

Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues.

Borland MK, Mohanakumar KP, Rubinstein JD, Keeney PM, Xie J, Capaldi R, Dunham LD, Trimmer PA, Bennett JP Jr.

Biochim Biophys Acta. 2009 Jan;1792(1):68-74. doi: 10.1016/j.bbadis.2008.09.014. Epub 2008 Oct 10.

PMID:
18973805
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Nitric oxide impairs mitochondrial movement in cortical neurons during hypoxia.

Zanelli SA, Trimmer PA, Solenski NJ.

J Neurochem. 2006 May;97(3):724-36. Epub 2006 Apr 5.

PMID:
16606371
[PubMed - indexed for MEDLINE]
8.

Differentiated Alzheimer's disease transmitochondrial cybrid cell lines exhibit reduced organelle movement.

Trimmer PA, Borland MK.

Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1101-9.

PMID:
16115014
[PubMed - indexed for MEDLINE]
9.

Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies.

Trimmer PA, Borland MK, Keeney PM, Bennett JP Jr, Parker WD Jr.

J Neurochem. 2004 Feb;88(4):800-12.

PMID:
14756800
[PubMed - indexed for MEDLINE]
10.

Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture.

Trimmer PA, Keeney PM, Borland MK, Simon FA, Almeida J, Swerdlow RH, Parks JP, Parker WD Jr, Bennett JP Jr.

Neurobiol Dis. 2004 Feb;15(1):29-39.

PMID:
14751768
[PubMed - indexed for MEDLINE]
11.

Ultrastructural changes of neuronal mitochondria after transient and permanent cerebral ischemia.

Solenski NJ, diPierro CG, Trimmer PA, Kwan AL, Helm GA.

Stroke. 2002 Mar;33(3):816-24. Erratum in: Stroke 2002 Apr;33(4):1171. Helms Gregory A [corrected to Helm Gregory A].

PMID:
11872909
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Chronic reduction in complex I function alters calcium signaling in SH-SY5Y neuroblastoma cells.

Sherer TB, Trimmer PA, Borland K, Parks JK, Bennett JP Jr, Tuttle JB.

Brain Res. 2001 Feb 9;891(1-2):94-105.

PMID:
11164812
[PubMed - indexed for MEDLINE]
14.

Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways.

Khan SM, Cassarino DS, Abramova NN, Keeney PM, Borland MK, Trimmer PA, Krebs CT, Bennett JC, Parks JK, Swerdlow RH, Parker WD Jr, Bennett JP Jr.

Ann Neurol. 2000 Aug;48(2):148-55.

PMID:
10939564
[PubMed - indexed for MEDLINE]
15.

Mitochondrial DNA-depleted neuroblastoma (Rho degrees) cells exhibit altered calcium signaling.

Sherer TB, Trimmer PA, Parks JK, Tuttle JB.

Biochim Biophys Acta. 2000 Apr 17;1496(2-3):341-55.

PMID:
10771102
[PubMed - indexed for MEDLINE]
Free Article
16.

Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines.

Trimmer PA, Swerdlow RH, Parks JK, Keeney P, Bennett JP Jr, Miller SW, Davis RE, Parker WD Jr.

Exp Neurol. 2000 Mar;162(1):37-50.

PMID:
10716887
[PubMed - indexed for MEDLINE]
17.

Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family.

Swerdlow RH, Parks JK, Davis JN 2nd, Cassarino DS, Trimmer PA, Currie LJ, Dougherty J, Bridges WS, Bennett JP Jr, Wooten GF, Parker WD.

Ann Neurol. 1998 Dec;44(6):873-81.

PMID:
9851431
[PubMed - indexed for MEDLINE]
18.

Mitochondria in sporadic amyotrophic lateral sclerosis.

Swerdlow RH, Parks JK, Cassarino DS, Trimmer PA, Miller SW, Maguire DJ, Sheehan JP, Maguire RS, Pattee G, Juel VC, Phillips LH, Tuttle JB, Bennett JP Jr, Davis RE, Parker WD Jr.

Exp Neurol. 1998 Sep;153(1):135-42.

PMID:
9743575
[PubMed - indexed for MEDLINE]

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