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Results: 1 to 20 of 74

1.

Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells.

Chang CW, Lai YS, Lamb LS Jr, Townes TM.

PLoS One. 2014 May 14;9(5):e97335. doi: 10.1371/journal.pone.0097335. eCollection 2014.

2.

The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment.

Yang W, Lee YH, Jones AE, Woolnough JL, Zhou D, Dai Q, Wu Q, Giles KE, Townes TM, Wang H.

Nat Commun. 2014 May 2;5:3818. doi: 10.1038/ncomms4818.

3.

USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.

Zhang Z, Jones A, Joo HY, Zhou D, Cao Y, Chen S, Erdjument-Bromage H, Renfrow M, He H, Tempst P, Townes TM, Giles KE, Ma L, Wang H.

Genes Dev. 2013 Jul 15;27(14):1581-95. doi: 10.1101/gad.211037.112. Epub 2013 Jul 3.

4.

FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin.

Kode A, Mosialou I, Silva BC, Rached MT, Zhou B, Wang J, Townes TM, Hen R, DePinho RA, Guo XE, Kousteni S.

J Clin Invest. 2012 Oct;122(10):3490-503. doi: 10.1172/JCI64906. Epub 2012 Sep 4.

5.

Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells.

Young MA, Larson DE, Sun CW, George DR, Ding L, Miller CA, Lin L, Pawlik KM, Chen K, Fan X, Schmidt H, Kalicki-Veizer J, Cook LL, Swift GW, Demeter RT, Wendl MC, Sands MS, Mardis ER, Wilson RK, Townes TM, Ley TJ.

Cell Stem Cell. 2012 May 4;10(5):570-82. doi: 10.1016/j.stem.2012.03.002. Epub 2012 Apr 26.

6.

Heme-regulated eIF2╬▒ kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis.

Suragani RN, Zachariah RS, Velazquez JG, Liu S, Sun CW, Townes TM, Chen JJ.

Blood. 2012 May 31;119(22):5276-84. doi: 10.1182/blood-2011-10-388132. Epub 2012 Apr 12.

7.

SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency.

Lai YS, Chang CW, Pawlik KM, Zhou D, Renfrow MB, Townes TM.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3772-7. doi: 10.1073/pnas.1108595109. Epub 2012 Feb 23.

8.

PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming.

Zhang Z, Jones A, Sun CW, Li C, Chang CW, Joo HY, Dai Q, Mysliwiec MR, Wu LC, Guo Y, Yang W, Liu K, Pawlik KM, Erdjument-Bromage H, Tempst P, Lee Y, Min J, Townes TM, Wang H.

Stem Cells. 2011 Feb;29(2):229-40. doi: 10.1002/stem.578.

9.

Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection.

Lin WJ, Zheng X, Lin CC, Tsao J, Zhu X, Cody JJ, Coleman JM, Gherzi R, Luo M, Townes TM, Parker JN, Chen CY.

Mol Cell Biol. 2011 Aug;31(16):3196-207. doi: 10.1128/MCB.05073-11. Epub 2011 Jun 20.

10.

Negative regulation of IRF7 activation by activating transcription factor 4 suggests a cross-regulation between the IFN responses and the cellular integrated stress responses.

Liang Q, Deng H, Sun CW, Townes TM, Zhu F.

J Immunol. 2011 Jan 15;186(2):1001-10. doi: 10.4049/jimmunol.1002240. Epub 2010 Dec 8.

11.

KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching.

Zhou D, Liu K, Sun CW, Pawlik KM, Townes TM.

Nat Genet. 2010 Sep;42(9):742-4. doi: 10.1038/ng.637. Epub 2010 Aug 1.

PMID:
20676097
12.

Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells.

Chang CW, Lai YS, Pawlik KM, Liu K, Sun CW, Li C, Schoeb TR, Townes TM.

Stem Cells. 2009 May;27(5):1042-9. doi: 10.1002/stem.39.

13.

Gene replacement therapy for sickle cell disease and other blood disorders.

Townes TM.

Hematology Am Soc Hematol Educ Program. 2008:193-6. doi: 10.1182/asheducation-2008.1.193.

14.

Global reorganization of replication domains during embryonic stem cell differentiation.

Hiratani I, Ryba T, Itoh M, Yokochi T, Schwaiger M, Chang CW, Lyou Y, Townes TM, Sch├╝beler D, Gilbert DM.

PLoS Biol. 2008 Oct 7;6(10):e245. doi: 10.1371/journal.pbio.0060245.

15.

SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation.

Isbell TS, Sun CW, Wu LC, Teng X, Vitturi DA, Branch BG, Kevil CG, Peng N, Wyss JM, Ambalavanan N, Schwiebert L, Ren J, Pawlik KM, Renfrow MB, Patel RP, Townes TM.

Nat Med. 2008 Jul;14(7):773-7. doi: 10.1038/nm1771. Epub 2008 May 30.

16.

ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo.

Lange PS, Chavez JC, Pinto JT, Coppola G, Sun CW, Townes TM, Geschwind DH, Ratan RR.

J Exp Med. 2008 May 12;205(5):1227-42. doi: 10.1084/jem.20071460. Epub 2008 May 5.

17.

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.

Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R.

Science. 2007 Dec 21;318(5858):1920-3. Epub 2007 Dec 6.

18.

Alterations in expression and chromatin configuration of the alpha hemoglobin-stabilizing protein gene in erythroid Kruppel-like factor-deficient mice.

Pilon AM, Nilson DG, Zhou D, Sangerman J, Townes TM, Bodine DM, Gallagher PG.

Mol Cell Biol. 2006 Jun;26(11):4368-77.

19.

Correction of sickle cell disease by homologous recombination in embryonic stem cells.

Wu LC, Sun CW, Ryan TM, Pawlik KM, Ren J, Townes TM.

Blood. 2006 Aug 15;108(4):1183-8. Epub 2006 Apr 25.

20.

Differential binding of erythroid Krupple-like factor to embryonic/fetal globin gene promoters during development.

Zhou D, Pawlik KM, Ren J, Sun CW, Townes TM.

J Biol Chem. 2006 Jun 9;281(23):16052-7. Epub 2006 Apr 10.

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