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Items: 1 to 20 of 26


Deciphering the therapeutic mechanisms of Xiao-Ke-An in treatment of type 2 diabetes in mice by a Fangjiomics approach.

Yang ZZ, Liu W, Zhang F, Li Z, Cheng YY.

Acta Pharmacol Sin. 2015 Jun;36(6):699-707. doi: 10.1038/aps.2014.138. Epub 2015 May 11.


Molecular network-based analysis of guizhi-shaoyao-zhimu decoction, a TCM herbal formula, for treatment of diabetic peripheral neuropathy.

Zhao N, Li J, Li L, Niu XY, Jiang M, He XJ, Bian ZX, Zhang G, Lu AP.

Acta Pharmacol Sin. 2015 Jun;36(6):716-23. doi: 10.1038/aps.2015.15. Epub 2015 Apr 27.


Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine model.

Kogelman LJ, Cirera S, Zhernakova DV, Fredholm M, Franke L, Kadarmideen HN.

BMC Med Genomics. 2014 Sep 30;7:57. doi: 10.1186/1755-8794-7-57.


Systems analysis and the prediction and prevention of Type 2 diabetes mellitus.

Bergman RN, Stefanovski D, Kim SP.

Curr Opin Biotechnol. 2014 Aug;28:165-70. doi: 10.1016/j.copbio.2014.05.007. Epub 2014 Jun 27. Review.


The pathogenesis of obesity from a genomic and systems biology perspective.

Levian C, Ruiz E, Yang X.

Yale J Biol Med. 2014 Jun 6;87(2):113-26. eCollection 2014 Jun. Review.


Integrative network analysis unveils convergent molecular pathways in Parkinson's disease and diabetes.

Santiago JA, Potashkin JA.

PLoS One. 2013 Dec 20;8(12):e83940. doi: 10.1371/journal.pone.0083940. eCollection 2013.


Systems biology approach to identify alterations in the stem cell reservoir of subcutaneous adipose tissue in a rat model of diabetes: effects on differentiation potential and function.

Ferrer-Lorente R, Bejar MT, Tous M, Vilahur G, Badimon L.

Diabetologia. 2014 Jan;57(1):246-56. doi: 10.1007/s00125-013-3081-z. Epub 2013 Oct 17.


Differential effects of drug interventions and dietary lifestyle in developing type 2 diabetes and complications: a systems biology analysis in LDLr-/- mice.

Radonjic M, Wielinga PY, Wopereis S, Kelder T, Goelela VS, Verschuren L, Toet K, van Duyvenvoorde W, van der Werff van der Vat B, Stroeve JH, Cnubben N, Kooistra T, van Ommen B, Kleemann R.

PLoS One. 2013;8(2):e56122. doi: 10.1371/journal.pone.0056122. Epub 2013 Feb 15.


Systems biology approach reveals genome to phenome correlation in type 2 diabetes.

Jain P, Vig S, Datta M, Jindel D, Mathur AK, Mathur SK, Sharma A.

PLoS One. 2013;8(1):e53522. doi: 10.1371/journal.pone.0053522. Epub 2013 Jan 7.


Systems biology: building a useful model from multiple markers and profiles.

Mayer P, Mayer B, Mayer G.

Nephrol Dial Transplant. 2012 Nov;27(11):3995-4002. doi: 10.1093/ndt/gfs489. Review.


A computational procedure for identifying master regulator candidates: a case study on diabetes progression in Goto-Kakizaki rats.

Piao G, Saito S, Sun Y, Liu ZP, Wang Y, Han X, Wu J, Zhou H, Chen L, Horimoto K.

BMC Syst Biol. 2012;6 Suppl 1:S2. doi: 10.1186/1752-0509-6-S1-S2. Epub 2012 Jul 16.


Perspectives on systems biology applications in diabetic kidney disease.

Komorowsky CV, Brosius FC 3rd, Pennathur S, Kretzler M.

J Cardiovasc Transl Res. 2012 Aug;5(4):491-508. doi: 10.1007/s12265-012-9382-7. Epub 2012 Jun 26. Review.


Proteomics and systems biology for understanding diabetic nephropathy.

Starkey JM, Tilton RG.

J Cardiovasc Transl Res. 2012 Aug;5(4):479-90. doi: 10.1007/s12265-012-9372-9. Epub 2012 May 12. Review.


Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease.

Greenblum S, Turnbaugh PJ, Borenstein E.

Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):594-9. doi: 10.1073/pnas.1116053109. Epub 2011 Dec 19.


Overview of symposium "Systems Genetics in Nutrition and Obesity Research".

Kalupahana NS, Moustaid-Moussa N.

J Nutr. 2011 Mar;141(3):512-4. doi: 10.3945/jn.110.130104. Epub 2011 Jan 26.


Genes and pathways contributing to obesity: a systems biology view.

Drake TA.

Prog Mol Biol Transl Sci. 2010;94:9-38. doi: 10.1016/S1877-1173(10)94002-7. Review.


Closed-loop control of artificial pancreatic Beta -cell in type 1 diabetes mellitus using model predictive iterative learning control.

Wang Y, Dassau E, Doyle FJ 3rd.

IEEE Trans Biomed Eng. 2010 Feb;57(2):211-9. doi: 10.1109/TBME.2009.2024409. Epub 2009 Jun 12.


Complex systems modeling for obesity research.

Hammond RA.

Prev Chronic Dis. 2009 Jul;6(3):A97. Epub 2009 Jun 15. Review.


A systems-oriented multilevel framework for addressing obesity in the 21st century.

Huang TT, Drewnosksi A, Kumanyika S, Glass TA.

Prev Chronic Dis. 2009 Jul;6(3):A82. Epub 2009 Jun 15. No abstract available.


Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes.

Eizirik DL, Moore F, Flamez D, Ortis F.

Biochem Soc Trans. 2008 Jun;36(Pt 3):321-7. doi: 10.1042/BST0360321. Review.

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