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Results: 1 to 20 of 166

Select item 236016391.

Highly enantioselective catalytic synthesis of neurite growth-promoting secoyohimbanes.

Antonchick AP, López-Tosco S, Parga J, Sievers S, Schürmann M, Preut H, Höing S, Schöler HR, Sterneckert J, Rauh D, Waldmann H.

Chem Biol. 2013 Apr 18;20(4):500-9. doi: 10.1016/j.chembiol.2013.03.011.

PMID:: 23601639; [PubMed - in process]

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Select item 235336082.

Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.

Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, Gasser T, Schöler HR, Sterneckert J.

PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22.

PMID:: 23533608; [PubMed - in process]

Free PMC Article

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Select item 235250193.

Conversion of genomic imprinting by reprogramming and redifferentiation.

Kim MJ, Choi HW, Jang HJ, Chung HM, Arauzo-Bravo MJ, Schöler HR, Do JT.

J Cell Sci. 2013 Apr 22. [Epub ahead of print]

PMID:: 23525019; [PubMed - as supplied by publisher]

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Select item 235036604.

A central role for TFIID in the pluripotent transcription circuitry.

Pijnappel WW, Esch D, Baltissen MP, Wu G, Mischerikow N, Bergsma AJ, van der Wal E, Han DW, Bruch Hv, Moritz S, Lijnzaad P, Altelaar AF, Sameith K, Zaehres H, Heck AJ, Holstege FC, Schöler HR, Timmers HT.

Nature. 2013 Mar 28;495(7442):516-9. doi: 10.1038/nature11970. Epub 2013 Mar 17.

PMID:: 23503660; [PubMed - indexed for MEDLINE]

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Select item 234861895.

Rapid and efficient generation of neurons from human pluripotent stem cells in a multititre plate format.

Zhang M, Schöler HR, Greber B.

J Vis Exp. 2013 Mar 5;(73):e4335. doi: 10.3791/4335.

PMID:: 23486189; [PubMed - in process]

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Select item 234728746.

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.

Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T, Maisel M, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler HR, Sterneckert J.

Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008.

PMID:: 23472874; [PubMed - in process]

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Select item 234345907.

Parthenogenetic stem cells for tissue-engineered heart repair.

Didié M, Christalla P, Rubart M, Muppala V, Döker S, Unsöld B, El-Armouche A, Rau T, Eschenhagen T, Schwoerer AP, Ehmke H, Schumacher U, Fuchs S, Lange C, Becker A, Tao W, Scherschel JA, Soonpaa MH, Yang T, Lin Q, Zenke M, Han DW, Schöler HR, Rudolph C, Steinemann D, Schlegelberger B, Kattman S, Witty A, Keller G, Field LJ, Zimmermann WH.

J Clin Invest. 2013 Mar 1;123(3):1285-98. doi: 10.1172/JCI66854. Epub 2013 Feb 22.

PMID:: 23434590; [PubMed - indexed for MEDLINE]

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Select item 233769738.

A unique Oct4 interface is crucial for reprogramming to pluripotency.

Esch D, Vahokoski J, Groves MR, Pogenberg V, Cojocaru V, Vom Bruch H, Han D, Drexler HC, Araúzo-Bravo MJ, Ng CK, Jauch R, Wilmanns M, Schöler HR.

Nat Cell Biol. 2013 Mar;15(3):295-301. doi: 10.1038/ncb2680. Epub 2013 Feb 3.

PMID:: 23376973; [PubMed - indexed for MEDLINE]

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Select item 233404229.

Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming.

Ruiz S, Gore A, Li Z, Panopoulos AD, Montserrat N, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Schöler HR, Zhang K, Izpisua Belmonte JC.

Nat Commun. 2013;4:1382. doi: 10.1038/ncomms2381.

PMID:: 23340422; [PubMed - in process]

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Select item 2323456210.

Expansion and differentiation of germline-derived pluripotent stem cells on biomaterials.

Hoss M, Šarić T, Denecke B, Peinkofer G, Bovi M, Groll J, Ko K, Salber J, Halbach M, Schöler HR, Zenke M, Neuss S.

Tissue Eng Part A. 2013 May;19(9-10):1067-80. doi: 10.1089/ten.TEA.2012.0185. Epub 2013 Feb 26.

PMID:: 23234562; [PubMed - in process]

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Select item 2323240911.

Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins.

Tapia N, Reinhardt P, Duemmler A, Wu G, Araúzo-Bravo MJ, Esch D, Greber B, Cojocaru V, Rascon CA, Tazaki A, Kump K, Voss R, Tanaka EM, Schöler HR.

Nat Commun. 2012;3:1279. doi: 10.1038/ncomms2229.

PMID:: 23232409; [PubMed - in process]

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Select item 2320956312.

Comprehensive human transcription factor binding site map for combinatory binding motifs discovery.

Müller-Molina AJ, Schöler HR, Araúzo-Bravo MJ.

PLoS One. 2012;7(11):e49086. doi: 10.1371/journal.pone.0049086. Epub 2012 Nov 28.

PMID:: 23209563; [PubMed - in process]

Free PMC Article

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Select item 2306410113.

Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay.

Höing S, Rudhard Y, Reinhardt P, Glatza M, Stehling M, Wu G, Peiker C, Böcker A, Parga JA, Bunk E, Schwamborn JC, Slack M, Sterneckert J, Schöler HR.

Cell Stem Cell. 2012 Nov 2;11(5):620-32. doi: 10.1016/j.stem.2012.07.005. Epub 2012 Oct 11.

PMID:: 23064101; [PubMed - in process]

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Select item 2302229914.

REST and its downstream molecule Mek5 regulate survival of primordial germ cells.

Okamura D, Mochizuki K, Taniguchi H, Tokitake Y, Ikeda M, Yamada Y, Tournier C, Yamaguchi S, Tada T, Schöler HR, Matsui Y.

Dev Biol. 2012 Dec 15;372(2):190-202. doi: 10.1016/j.ydbio.2012.09.013. Epub 2012 Sep 26.

PMID:: 23022299; [PubMed - indexed for MEDLINE]

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Select item 2301113015.

Direct visualization of cell division using high-resolution imaging of M-phase of the cell cycle.

Hesse M, Raulf A, Pilz GA, Haberlandt C, Klein AM, Jabs R, Zaehres H, Fügemann CJ, Zimmermann K, Trebicka J, Welz A, Pfeifer A, Röll W, Kotlikoff MI, Steinhäuser C, Götz M, Schöler HR, Fleischmann BK.

Nat Commun. 2012;3:1076. doi: 10.1038/ncomms2089.

PMID:: 23011130; [PubMed - indexed for MEDLINE]

Free PMC Article

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Select item 2299147316.

Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells.

Ruiz S, Diep D, Gore A, Panopoulos AD, Montserrat N, Plongthongkum N, Kumar S, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Kan NG, Schöler HR, Mercola M, Zhang K, Izpisua Belmonte JC.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16196-201. doi: 10.1073/pnas.1202352109. Epub 2012 Sep 18.