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Results: 1 to 20 of 49

1.

Post-traumatic stress disorder, depression, and aggression in OEF/OIF veterans.

Angkaw AC, Ross BS, Pittman JO, Kelada AM, Valencerina MA, Baker DG.

Mil Med. 2013 Oct;178(10):1044-50. doi: 10.7205/MILMED-D-13-00061.

PMID:
24083916
[PubMed - in process]
2.

β-D-2'-α-F-2'-β-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship study.

Du J, Bao D, Chun BK, Jiang Y, Reddy PG, Zhang HR, Ross BS, Bansal S, Bao H, Espiritu C, Lam AM, Murakami E, Niu C, Micolochick Steuer HM, Furman PA, Otto MJ, Sofia MJ.

Bioorg Med Chem Lett. 2012 Sep 15;22(18):5924-9. doi: 10.1016/j.bmcl.2012.07.066. Epub 2012 Jul 27.

PMID:
22892115
[PubMed - indexed for MEDLINE]
3.

Rapid differentiation of nucleotide phosphoramidate diastereomers by electrospray ionization tandem mass spectrometry.

Bao D, Reddy PG, Ross BS, Sofia MJ.

Rapid Commun Mass Spectrom. 2012 Aug 30;26(16):1887-92. doi: 10.1002/rcm.6307.

PMID:
22777791
[PubMed - indexed for MEDLINE]
4.

Phosphoramidate prodrugs of (-)-β-D-(2R,4R)-dioxolane-thymine (DOT) as potent anti-HIV agents.

Wang P, Rachakonda S, Zennou V, Keilman M, Niu C, Bao D, Ross BS, Furman PA, Otto MJ, Sofia MJ.

Antivir Chem Chemother. 2012 May 14;22(5):217-38. doi: 10.3851/IMP2079.

PMID:
22358223
[PubMed - indexed for MEDLINE]
5.

Nucleoside, nucleotide, and non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA-polymerase.

Sofia MJ, Chang W, Furman PA, Mosley RT, Ross BS.

J Med Chem. 2012 Mar 22;55(6):2481-531. doi: 10.1021/jm201384j. Epub 2012 Jan 23. Review. No abstract available.

PMID:
22185586
[PubMed - indexed for MEDLINE]
6.

Synthesis of stable isotope labeled analogs of the anti-hepatitis C virus nucleotide prodrugs PSI-7977 and PSI-352938.

Chun BK, Du J, Zhang HR, Chang W, Ross BS, Jiang Y, Bao D, Espiritu CL, Keilman M, Steuer HM, Furman PA, Sofia MJ.

Nucleosides Nucleotides Nucleic Acids. 2011 Nov;30(11):886-96. doi: 10.1080/15257770.2011.614308.

PMID:
22060553
[PubMed - indexed for MEDLINE]
7.

Synthesis of diastereomerically pure nucleotide phosphoramidates.

Ross BS, Reddy PG, Zhang HR, Rachakonda S, Sofia MJ.

J Org Chem. 2011 Oct 21;76(20):8311-9. doi: 10.1021/jo201492m. Epub 2011 Sep 26.

PMID:
21916475
[PubMed - indexed for MEDLINE]
8.

A liquid chromatography-tandem mass spectrometry method for the quantitative determination of diastereomers of a phosphoramidate nucleotide prodrug (PSI-7851) in human plasma.

Bao D, Ross BS, Sofia MJ.

Biomed Chromatogr. 2012 May;26(5):583-8. doi: 10.1002/bmc.1678. Epub 2011 Aug 12.

PMID:
21842514
[PubMed - indexed for MEDLINE]
9.

Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661.

Furman PA, Murakami E, Niu C, Lam AM, Espiritu C, Bansal S, Bao H, Tolstykh T, Micolochick Steuer H, Keilman M, Zennou V, Bourne N, Veselenak RL, Chang W, Ross BS, Du J, Otto MJ, Sofia MJ.

Antiviral Res. 2011 Aug;91(2):120-32. doi: 10.1016/j.antiviral.2011.05.003. Epub 2011 May 12.

PMID:
21600932
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Stereoselective synthesis of PSI-352938: a β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl-3',5'-cyclic phosphate nucleotide prodrug for the treatment of HCV.

Reddy PG, Chun BK, Zhang HR, Rachakonda S, Ross BS, Sofia MJ.

J Org Chem. 2011 May 20;76(10):3782-90. doi: 10.1021/jo200060f. Epub 2011 Apr 19.

PMID:
21469736
[PubMed - indexed for MEDLINE]
11.

2'-deoxy-2'-α-fluoro-2'-β-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.

Reddy PG, Bao D, Chang W, Chun BK, Du J, Nagarathnam D, Rachakonda S, Ross BS, Zhang HR, Bansal S, Espiritu CL, Keilman M, Lam AM, Niu C, Steuer HM, Furman PA, Otto MJ, Sofia MJ.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7376-80. doi: 10.1016/j.bmcl.2010.10.035. Epub 2010 Oct 15.

PMID:
21050754
[PubMed - indexed for MEDLINE]
12.

Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus.

Sofia MJ, Bao D, Chang W, Du J, Nagarathnam D, Rachakonda S, Reddy PG, Ross BS, Wang P, Zhang HR, Bansal S, Espiritu C, Keilman M, Lam AM, Steuer HM, Niu C, Otto MJ, Furman PA.

J Med Chem. 2010 Oct 14;53(19):7202-18. doi: 10.1021/jm100863x.

PMID:
20845908
[PubMed - indexed for MEDLINE]
13.

Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.

Chang W, Du J, Rachakonda S, Ross BS, Convers-Reignier S, Yau WT, Pons JF, Murakami E, Bao H, Steuer HM, Furman PA, Otto MJ, Sofia MJ.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4539-43. doi: 10.1016/j.bmcl.2010.06.025. Epub 2010 Jun 8.

PMID:
20580554
[PubMed - indexed for MEDLINE]
14.

PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.

Lam AM, Murakami E, Espiritu C, Steuer HM, Niu C, Keilman M, Bao H, Zennou V, Bourne N, Julander JG, Morrey JD, Smee DF, Frick DN, Heck JA, Wang P, Nagarathnam D, Ross BS, Sofia MJ, Otto MJ, Furman PA.

Antimicrob Agents Chemother. 2010 Aug;54(8):3187-96. doi: 10.1128/AAC.00399-10. Epub 2010 Jun 1.

PMID:
20516278
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase.

Wang P, Chun BK, Rachakonda S, Du J, Khan N, Shi J, Stec W, Cleary D, Ross BS, Sofia MJ.

J Org Chem. 2009 Sep 4;74(17):6819-24. doi: 10.1021/jo901345j.

PMID:
19642660
[PubMed - indexed for MEDLINE]
16.

Process research on the preparation of DMT protected 2'-O-methoxyethylguanosine for oligonucleotide synthesis in therapeutic applications.

Taj SA, Narayanan S, Meenakshi SS, Sanghvi YS, Ross BS, Ravikumar VT.

Nucleosides Nucleotides Nucleic Acids. 2008 Sep;27(9):1024-33. doi: 10.1080/15257770802271748.

PMID:
18711665
[PubMed - indexed for MEDLINE]
17.

Comparing in vitro and in vivo activity of 2'-O-[2-(methylamino)-2-oxoethyl]- and 2'-O-methoxyethyl-modified antisense oligonucleotides.

Prakash TP, Kawasaki AM, Wancewicz EV, Shen L, Monia BP, Ross BS, Bhat B, Manoharan M.

J Med Chem. 2008 May 8;51(9):2766-76. doi: 10.1021/jm701537z. Epub 2008 Apr 10.

PMID:
18399648
[PubMed - indexed for MEDLINE]
18.

An efficient and scalable synthesis of 2,6-diaminopurine riboside.

Ross BS, Springer RH, Ravikumar VT.

Nucleosides Nucleotides Nucleic Acids. 2008 Jan;27(1):67-9. doi: 10.1080/15257770701571990.

PMID:
18188771
[PubMed - indexed for MEDLINE]
19.

Capabilities of neurexins in the chick ciliary ganglion.

Ross BS, Conroy WG.

Dev Neurobiol. 2008 Feb 15;68(3):409-19.

PMID:
18161851
[PubMed - indexed for MEDLINE]
20.

Implementation and refinement of a problem-based learning model: a ten-year experience.

Ross LA, Crabtree BL, Theilman GD, Ross BS, Cleary JD, Byrd HJ.

Am J Pharm Educ. 2007 Feb 15;71(1):17.

PMID:
17429517
[PubMed - indexed for MEDLINE]
Free PMC Article

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