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Results: 1 to 20 of 52

1.

A Human ErbB2-Specific T-Cell Receptor Confers Potent Antitumor Effector Functions in Genetically Engineered Primary Cytotoxic Lymphocytes.

Lanitis E, Smith JB, Dangaj D, Flingai S, Poussin M, Xu S, Czerniecki BJ, Li YF, Robbins PF, Powell DJ Jr.

Hum Gene Ther. 2014 Aug;25(8):730-9. doi: 10.1089/hum.2014.006.

PMID:
25003657
[PubMed - in process]
2.

B7-H4 as a potential target for immunotherapy for gynecologic cancers: a closer look.

Smith JB, Stashwick C, Powell DJ Jr.

Gynecol Oncol. 2014 Jul;134(1):181-9. doi: 10.1016/j.ygyno.2014.03.553. Epub 2014 Mar 20. Review.

PMID:
24657487
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Chimeric antigen receptor T Cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo.

Lanitis E, Poussin M, Klattenhoff AW, Song D, Sandaltzopoulos R, June CH, Powell DJ Jr.

Cancer Immunol Res. 2013 Jul;1(1):43-53.

PMID:
24409448
[PubMed - in process]
Free PMC Article
4.

Therapeutic dendritic cell-based cancer vaccines: the state of the art.

Strioga MM, Felzmann T, Powell DJ Jr, Ostapenko V, Dobrovolskiene NT, Matuskova M, Michalek J, Schijns VE.

Crit Rev Immunol. 2013;33(6):489-547. Review.

PMID:
24266347
[PubMed - indexed for MEDLINE]
5.

CD137 accurately identifies and enriches for naturally occurring tumor-reactive T cells in tumor.

Ye Q, Song DG, Poussin M, Yamamoto T, Best A, Li C, Coukos G, Powell DJ Jr.

Clin Cancer Res. 2014 Jan 1;20(1):44-55. doi: 10.1158/1078-0432.CCR-13-0945. Epub 2013 Sep 17.

PMID:
24045181
[PubMed - indexed for MEDLINE]
6.

A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: from bench to bedside.

Chiang CL, Kandalaft LE, Tanyi J, Hagemann AR, Motz GT, Svoronos N, Montone K, Mantia-Smaldone GM, Smith L, Nisenbaum HL, Levine BL, Kalos M, Czerniecki BJ, Torigian DA, Powell DJ Jr, Mick R, Coukos G.

Clin Cancer Res. 2013 Sep 1;19(17):4801-15. doi: 10.1158/1078-0432.CCR-13-1185. Epub 2013 Jul 9.

PMID:
23838316
[PubMed - indexed for MEDLINE]
7.

Novel recombinant human b7-h4 antibodies overcome tumoral immune escape to potentiate T-cell antitumor responses.

Dangaj D, Lanitis E, Zhao A, Joshi S, Cheng Y, Sandaltzopoulos R, Ra HJ, Danet-Desnoyers G, Powell DJ Jr, Scholler N.

Cancer Res. 2013 Aug 1;73(15):4820-9. doi: 10.1158/0008-5472.CAN-12-3457. Epub 2013 May 30.

PMID:
23722540
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Remarkable stability of clinical grade reagents for gene-engineered T-lymphocyte production.

Johnson LA, Powell DJ Jr.

Cytotherapy. 2013 May;15(5):523-4. doi: 10.1016/j.jcyt.2013.02.012. No abstract available.

PMID:
23541089
[PubMed - indexed for MEDLINE]
9.

Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer.

Kandalaft LE, Powell DJ Jr, Chiang CL, Tanyi J, Kim S, Bosch M, Montone K, Mick R, Levine BL, Torigian DA, June CH, Coukos G.

Oncoimmunology. 2013 Jan 1;2(1):e22664.

PMID:
23482679
[PubMed]
Free PMC Article
10.

IL-21 promotes the expansion of CD27+ CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells.

Santegoets SJ, Turksma AW, Suhoski MM, Stam AG, Albelda SM, Hooijberg E, Scheper RJ, van den Eertwegh AJ, Gerritsen WR, Powell DJ Jr, June CH, de Gruijl TD.

J Transl Med. 2013 Feb 12;11:37. doi: 10.1186/1479-5876-11-37.

PMID:
23402380
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Chimeric NKG2D CAR-expressing T cell-mediated attack of human ovarian cancer is enhanced by histone deacetylase inhibition.

Song DG, Ye Q, Santoro S, Fang C, Best A, Powell DJ Jr.

Hum Gene Ther. 2013 Mar;24(3):295-305. doi: 10.1089/hum.2012.143. Epub 2013 Mar 1.

PMID:
23297870
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Primary human ovarian epithelial cancer cells broadly express HER2 at immunologically-detectable levels.

Lanitis E, Dangaj D, Hagemann IS, Song DG, Best A, Sandaltzopoulos R, Coukos G, Powell DJ Jr.

PLoS One. 2012;7(11):e49829. doi: 10.1371/journal.pone.0049829. Epub 2012 Nov 26.

PMID:
23189165
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous T cells for recurrent ovarian cancer.

Kandalaft LE, Powell DJ Jr, Coukos G.

J Transl Med. 2012 Aug 3;10:157. doi: 10.1186/1479-5876-10-157.

PMID:
22863016
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Dendritic cells and their role in tumor immunosurveillance.

Strioga M, Schijns V, Powell DJ Jr, Pasukoniene V, Dobrovolskiene N, Michalek J.

Innate Immun. 2013 Feb;19(1):98-111. doi: 10.1177/1753425912449549. Epub 2012 Jun 25. Review.

PMID:
22732734
[PubMed - indexed for MEDLINE]
15.

CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients.

Rech AJ, Mick R, Martin S, Recio A, Aqui NA, Powell DJ Jr, Colligon TA, Trosko JA, Leinbach LI, Pletcher CH, Tweed CK, DeMichele A, Fox KR, Domchek SM, Riley JL, Vonderheide RH.

Sci Transl Med. 2012 May 16;4(134):134ra62. doi: 10.1126/scitranslmed.3003330.

PMID:
22593175
[PubMed - indexed for MEDLINE]
Free Article
16.

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer.

Stroncek DF, Berger C, Cheever MA, Childs RW, Dudley ME, Flynn P, Gattinoni L, Heath JR, Kalos M, Marincola FM, Miller JS, Mostoslavsky G, Powell DJ Jr, Rao M, Restifo NP, Rosenberg SA, O'Shea J, Melief CJ.

J Transl Med. 2012 Mar 15;10:48. doi: 10.1186/1479-5876-10-48.

PMID:
22420641
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor.

Urbanska K, Lanitis E, Poussin M, Lynn RC, Gavin BP, Kelderman S, Yu J, Scholler N, Powell DJ Jr.

Cancer Res. 2012 Apr 1;72(7):1844-52. doi: 10.1158/0008-5472.CAN-11-3890. Epub 2012 Feb 7.

PMID:
22315351
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses.

Chiang CL, Hagemann AR, Leskowitz R, Mick R, Garrabrant T, Czerniecki BJ, Kandalaft LE, Powell DJ Jr, Coukos G.

PLoS One. 2011;6(12):e28732. doi: 10.1371/journal.pone.0028732. Epub 2011 Dec 14.

PMID:
22194898
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mannose receptor (MR) engagement by mesothelin GPI anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody.

Dangaj D, Abbott KL, Mookerjee A, Zhao A, Kirby PS, Sandaltzopoulos R, Powell DJ Jr, Lamazière A, Siegel DL, Wolf C, Scholler N.

PLoS One. 2011;6(12):e28386. doi: 10.1371/journal.pone.0028386. Epub 2011 Dec 6.

PMID:
22163010
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Redirected antitumor activity of primary human lymphocytes transduced with a fully human anti-mesothelin chimeric receptor.

Lanitis E, Poussin M, Hagemann IS, Coukos G, Sandaltzopoulos R, Scholler N, Powell DJ Jr.

Mol Ther. 2012 Mar;20(3):633-43. doi: 10.1038/mt.2011.256. Epub 2011 Nov 29.

PMID:
22127019
[PubMed - indexed for MEDLINE]
Free PMC Article

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