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Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease.

Kumar DK, Choi SH, Washicosky KJ, Eimer WA, Tucker S, Ghofrani J, Lefkowitz A, McColl G, Goldstein LE, Tanzi RE, Moir RD.

Sci Transl Med. 2016 May 25;8(340):340ra72. doi: 10.1126/scitranslmed.aaf1059.


Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease.

Zhang X, Tian Y, Zhang C, Tian X, Ross AW, Moir RD, Sun H, Tanzi RE, Moore A, Ran C.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9734-9. doi: 10.1073/pnas.1505420112. Epub 2015 Jul 21.


Differential Phosphorylation of RNA Polymerase III and the Initiation Factor TFIIIB in Saccharomyces cerevisiae.

Lee J, Moir RD, Willis IM.

PLoS One. 2015 May 13;10(5):e0127225. doi: 10.1371/journal.pone.0127225. eCollection 2015.


Loss of the RNA polymerase III repressor MAF1 confers obesity resistance.

Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC Jr, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, Vaitheesvaran B, Kurland I, Hernandez N, Willis IM.

Genes Dev. 2015 May 1;29(9):934-47. doi: 10.1101/gad.258350.115.


Differential phosphorylation of a regulatory subunit of protein kinase CK2 by target of rapamycin complex 1 signaling and the Cdc-like kinase Kns1.

Sanchez-Casalongue ME, Lee J, Diamond A, Shuldiner S, Moir RD, Willis IM.

J Biol Chem. 2015 Mar 13;290(11):7221-33. doi: 10.1074/jbc.M114.626523. Epub 2015 Jan 28.


Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites.

Frame IJ, Deniskin R, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH.

ACS Chem Biol. 2015 Mar 20;10(3):775-83. doi: 10.1021/cb500981y. Epub 2015 Jan 30.


Regulating maf1 expression and its expanding biological functions.

Moir RD, Willis IM.

PLoS Genet. 2015 Jan 8;11(1):e1004896. doi: 10.1371/journal.pgen.1004896. eCollection 2015 Jan. No abstract available.


Synaptic abnormalities in a Drosophila model of Alzheimer's disease.

Mhatre SD, Satyasi V, Killen M, Paddock BE, Moir RD, Saunders AJ, Marenda DR.

Dis Model Mech. 2014 Mar;7(3):373-85. doi: 10.1242/dmm.012104. Epub 2014 Jan 30.


Regulation of pol III transcription by nutrient and stress signaling pathways.

Moir RD, Willis IM.

Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):361-75. doi: 10.1016/j.bbagrm.2012.11.001. Epub 2012 Nov 16. Review.


SCS3 and YFT2 link transcription of phospholipid biosynthetic genes to ER stress and the UPR.

Moir RD, Gross DA, Silver DL, Willis IM.

PLoS Genet. 2012 Aug;8(8):e1002890. doi: 10.1371/journal.pgen.1002890. Epub 2012 Aug 23.


Recovery of RNA polymerase III transcription from the glycerol-repressed state: revisiting the role of protein kinase CK2 in Maf1 phosphoregulation.

Moir RD, Lee J, Willis IM.

J Biol Chem. 2012 Aug 31;287(36):30833-41. doi: 10.1074/jbc.M112.378828. Epub 2012 Jul 18.


Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC.

Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716.


TOR signaling regulates ribosome and tRNA synthesis via LAMMER/Clk and GSK-3 family kinases.

Lee J, Moir RD, McIntosh KB, Willis IM.

Mol Cell. 2012 Mar 30;45(6):836-43. doi: 10.1016/j.molcel.2012.01.018. Epub 2012 Feb 23.


Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells.

Lajoie P, Moir RD, Willis IM, Snapp EL.

Mol Biol Cell. 2012 Mar;23(5):955-64. doi: 10.1091/mbc.E11-12-0995. Epub 2012 Jan 4.


Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization.

Zhang Y, Zhen Y, Dong Y, Xu Z, Yue Y, Golde TE, Tanzi RE, Moir RD, Xie Z.

PLoS One. 2011;6(11):e27019. doi: 10.1371/journal.pone.0027019. Epub 2011 Nov 1.


Does casein kinase II phosphorylation of Maf1 trigger RNA polymerase III activation?

Willis IM, Moir RD, Lee J.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):E300; author reply E301. doi: 10.1073/pnas.1107306108. Epub 2011 Jul 6. No abstract available.


Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects.

Chakraborty R, Vepuri V, Mhatre SD, Paddock BE, Miller S, Michelson SJ, Delvadia R, Desai A, Vinokur M, Melicharek DJ, Utreja S, Khandelwal P, Ansaloni S, Goldstein LE, Moir RD, Lee JC, Tabb LP, Saunders AJ, Marenda DR.

PLoS One. 2011;6(6):e20799. doi: 10.1371/journal.pone.0020799. Epub 2011 Jun 6.


Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species.

Ran C, Zhao W, Moir RD, Moore A.

PLoS One. 2011 Apr 29;6(4):e19362. doi: 10.1371/journal.pone.0019362.


Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.

Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI.

Cell. 2010 Sep 17;142(6):857-67. doi: 10.1016/j.cell.2010.08.014.


Alzheimer's disease amyloid-beta links lens and brain pathology in Down syndrome.

Moncaster JA, Pineda R, Moir RD, Lu S, Burton MA, Ghosh JG, Ericsson M, Soscia SJ, Mocofanescu A, Folkerth RD, Robb RM, Kuszak JR, Clark JI, Tanzi RE, Hunter DG, Goldstein LE.

PLoS One. 2010 May 20;5(5):e10659. doi: 10.1371/journal.pone.0010659.

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