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Results: 1 to 20 of 110

1.

Synaptic abnormalities in a Drosophila model of Alzheimer's disease.

Mhatre SD, Satyasi V, Killen M, Paddock BE, Moir RD, Saunders AJ, Marenda DR.

Dis Model Mech. 2014 Mar-Apr;7(3):373-85. doi: 10.1242/dmm.012104. Epub 2014 Jan 30.

PMID:
24487408
[PubMed - in process]
Free PMC Article
2.

Regulation of pol III transcription by nutrient and stress signaling pathways.

Moir RD, Willis IM.

Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):361-75. doi: 10.1016/j.bbagrm.2012.11.001. Epub 2012 Nov 16. Review.

PMID:
23165150
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

SCS3 and YFT2 link transcription of phospholipid biosynthetic genes to ER stress and the UPR.

Moir RD, Gross DA, Silver DL, Willis IM.

PLoS Genet. 2012 Aug;8(8):e1002890. doi: 10.1371/journal.pgen.1002890. Epub 2012 Aug 23.

PMID:
22927826
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Recovery of RNA polymerase III transcription from the glycerol-repressed state: revisiting the role of protein kinase CK2 in Maf1 phosphoregulation.

Moir RD, Lee J, Willis IM.

J Biol Chem. 2012 Aug 31;287(36):30833-41. doi: 10.1074/jbc.M112.378828. Epub 2012 Jul 18.

PMID:
22810236
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC.

Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716.

PMID:
22593173
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

TOR signaling regulates ribosome and tRNA synthesis via LAMMER/Clk and GSK-3 family kinases.

Lee J, Moir RD, McIntosh KB, Willis IM.

Mol Cell. 2012 Mar 30;45(6):836-43. doi: 10.1016/j.molcel.2012.01.018. Epub 2012 Feb 23.

PMID:
22364741
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells.

Lajoie P, Moir RD, Willis IM, Snapp EL.

Mol Biol Cell. 2012 Mar;23(5):955-64. doi: 10.1091/mbc.E11-12-0995. Epub 2012 Jan 4.

PMID:
22219379
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization.

Zhang Y, Zhen Y, Dong Y, Xu Z, Yue Y, Golde TE, Tanzi RE, Moir RD, Xie Z.

PLoS One. 2011;6(11):e27019. doi: 10.1371/journal.pone.0027019. Epub 2011 Nov 1.

PMID:
22069482
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Does casein kinase II phosphorylation of Maf1 trigger RNA polymerase III activation?

Willis IM, Moir RD, Lee J.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):E300; author reply E301. doi: 10.1073/pnas.1107306108. Epub 2011 Jul 6. No abstract available.

PMID:
21734148
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects.

Chakraborty R, Vepuri V, Mhatre SD, Paddock BE, Miller S, Michelson SJ, Delvadia R, Desai A, Vinokur M, Melicharek DJ, Utreja S, Khandelwal P, Ansaloni S, Goldstein LE, Moir RD, Lee JC, Tabb LP, Saunders AJ, Marenda DR.

PLoS One. 2011;6(6):e20799. doi: 10.1371/journal.pone.0020799. Epub 2011 Jun 6.

PMID:
21673973
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species.

Ran C, Zhao W, Moir RD, Moore A.

PLoS One. 2011 Apr 29;6(4):e19362. doi: 10.1371/journal.pone.0019362.

PMID:
21559413
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.

Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI.

Cell. 2010 Sep 17;142(6):857-67. doi: 10.1016/j.cell.2010.08.014.

PMID:
20817278
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Alzheimer's disease amyloid-beta links lens and brain pathology in Down syndrome.

Moncaster JA, Pineda R, Moir RD, Lu S, Burton MA, Ghosh JG, Ericsson M, Soscia SJ, Mocofanescu A, Folkerth RD, Robb RM, Kuszak JR, Clark JI, Tanzi RE, Hunter DG, Goldstein LE.

PLoS One. 2010 May 20;5(5):e10659. doi: 10.1371/journal.pone.0010659.

PMID:
20502642
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide.

Soscia SJ, Kirby JE, Washicosky KJ, Tucker SM, Ingelsson M, Hyman B, Burton MA, Goldstein LE, Duong S, Tanzi RE, Moir RD.

PLoS One. 2010 Mar 3;5(3):e9505. doi: 10.1371/journal.pone.0009505.

PMID:
20209079
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.

Kim M, Suh J, Romano D, Truong MH, Mullin K, Hooli B, Norton D, Tesco G, Elliott K, Wagner SL, Moir RD, Becker KD, Tanzi RE.

Hum Mol Genet. 2009 Oct 15;18(20):3987-96. doi: 10.1093/hmg/ddp323. Epub 2009 Jul 15.

PMID:
19608551
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels.

Dong Y, Zhang G, Zhang B, Moir RD, Xia W, Marcantonio ER, Culley DJ, Crosby G, Tanzi RE, Xie Z.

Arch Neurol. 2009 May;66(5):620-31. doi: 10.1001/archneurol.2009.48.

PMID:
19433662
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway.

Lee J, Moir RD, Willis IM.

J Biol Chem. 2009 May 8;284(19):12604-8. doi: 10.1074/jbc.C900020200. Epub 2009 Mar 19.

PMID:
19299514
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.

Myre MA, Washicosky K, Moir RD, Tesco G, Tanzi RE, Wasco W.

Cell Signal. 2009 Apr;21(4):567-76. doi: 10.1016/j.cellsig.2008.12.008. Epub 2008 Dec 25.

PMID:
19154786
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo.

Xie Z, Culley DJ, Dong Y, Zhang G, Zhang B, Moir RD, Frosch MP, Crosby G, Tanzi RE.

Ann Neurol. 2008 Dec;64(6):618-27. doi: 10.1002/ana.21548.

PMID:
19006075
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes.

Willis IM, Chua G, Tong AH, Brost RL, Hughes TR, Boone C, Moir RD.

PLoS Genet. 2008 Jul 4;4(7):e1000112. doi: 10.1371/journal.pgen.1000112.

PMID:
18604275
[PubMed - indexed for MEDLINE]
Free PMC Article

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