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Items: 1 to 20 of 51


O-015 YI Alterations in the FOXP3-EZH2 Pathway Associates with Increased Susceptibility to Colitis in Both Mice and Human.

Sarmento O, Xiong Y, Sun Z, Svingen P, Bamidele A, Smyrk T, Nair A, Baheti S, McGovern D, Friton J, Papadakis K, Goel G, Xavier R, Urrutia R, Faubion W.

Inflamm Bowel Dis. 2016 Mar;22 Suppl 1:S5-6. doi: 10.1097/01.MIB.0000480101.02647.09.


O-011 Paneth Cell Phenotypes Define a Subtype of Pediatric Crohn's Disease Through Alterations in Host-Microbial Interactions.

Liu TC, Gurram B, Baldridge M, Head R, Lam V, Luo C, Cao Y, Simpson P, Hayward M, Holtz M, Noe J, Lerner D, Cabrera J, Biank V, Stephens M, Huttenhower C, McGovern D, Xavier R, Stappenbeck T, Salzman N.

Inflamm Bowel Dis. 2016 Mar;22 Suppl 1:S4. doi: 10.1097/01.MIB.0000480097.23732.5e.


O-004 Analysis of Chromatin and Transcriptional Profiles in Crohn's Disease Reveals Molecular Subclasses and Highlights Functional Regulatory Regions Implicated in Disease.

Weiser M, Sheikh S, Kochar B, Gipson G, Herfarth H, Sartor R, McGovern D, Rahbar R, Sadiq T, Furey T, Koruda M, Robinson A.

Inflamm Bowel Dis. 2016 Mar;22 Suppl 1:S1-2. doi: 10.1097/01.MIB.0000480042.88631.e4.


O-002 Genes in IBD-Associated Risk Loci Demonstrate Genotype-, Tissue-, and Inflammation-Specific Patterns of Expression in Terminal Ileum and Colon Mucosal Tissue.

Peloquin J, Goel G, Huang H, Haritunians T, Sartor R, Daly M, Newberry R, McGovern D, Lira S, Xavier R.

Inflamm Bowel Dis. 2016 Mar;22 Suppl 1:S1. doi: 10.1097/01.MIB.0000480040.50582.81.


CA19-9 decrease at 8 weeks as a predictor of overall survival in a randomized phase III trial (MPACT) of weekly nab-paclitaxel plus gemcitabine vs gemcitabine alone in patients with metastatic pancreatic cancer.

Chiorean EG, Von Hoff DD, Reni M, Arena FP, Infante JR, Bathini VG, Wood TE, Mainwaring PN, Muldoon RT, Clingan PR, Kunzmann V, Ramanathan RK, Tabernero J, Goldstein D, McGovern D, Lu B, Ko A.

Ann Oncol. 2016 Jan 22. pii: mdw006. [Epub ahead of print]


Positron Emission Tomography Response Evaluation from a Randomized Phase III Trial of Weekly nab-Paclitaxel Plus Gemcitabine vs Gemcitabine Alone for Patients With Metastatic Adenocarcinoma of the Pancreas.

Ramanathan RK, Goldstein D, Korn RL, Arena F, Moore M, Siena S, Teixeira L, Tabernero J, Van Laethem JL, Liu H, McGovern D, Lu B, Von Hoff DD.

Ann Oncol. 2016 Jan 22. pii: mdw020. [Epub ahead of print]


Nonbloody Diarrhea but Not Significant Weight Loss at Diagnosis Is Associated with the Development of Denovo Crohn's Disease After Ileal Pouch-anal Anastomosis for Ulcerative Colitis.

Ahmed S, Melmed G, McGovern D, Robbins LA, Shih D, Vasiliauskas E, Singh N, Rabidzadeh S, Ippoliti A, Targan S, Fleshner P.

Inflamm Bowel Dis. 2016 Mar;22(3):654-61. doi: 10.1097/MIB.0000000000000630.


A novel role for KLF14 in T regulatory cell differentiation.

Sarmento OF, Svingen PA, Xiong Y, Xavier RJ, McGovern D, Smyrk TC, Papadakis KA, Urrutia RA, Faubion WA.

Cell Mol Gastroenterol Hepatol. 2015 Mar 1;1(2):188-202.e4.


Variation in treatment of patients with inflammatory bowel diseases at major referral centers in the United States.

Ananthakrishnan AN, Kwon J, Raffals L, Sands B, Stenson WF, McGovern D, Kwon JH, Rheaume RL, Sandler RS.

Clin Gastroenterol Hepatol. 2015 Jun;13(6):1197-200. doi: 10.1016/j.cgh.2014.11.020. Epub 2014 Nov 21.


Molecular patterns in human ulcerative colitis and correlation with response to infliximab.

Halloran B, Chang J, Shih DQ, McGovern D, Famulski K, Evaschesen C, Fedorak RN, Thiesen A, Targan S, Halloran PF.

Inflamm Bowel Dis. 2014 Dec;20(12):2353-63. doi: 10.1097/MIB.0000000000000239.


Should biologic agents be stopped before surgery for inflammatory bowel disease?

Zaghiyan K, McGovern D, Fleshner P.

Expert Rev Gastroenterol Hepatol. 2015 Mar;9(3):269-72. doi: 10.1586/17474124.2015.975208. Epub 2014 Nov 4. Review.


Decellularized tracheal extracellular matrix supports epithelial migration, differentiation, and function.

Kutten JC, McGovern D, Hobson CM, Luffy SA, Nieponice A, Tobita K, Francis RJ, Reynolds SD, Isenberg JS, Gilbert TW.

Tissue Eng Part A. 2015 Jan;21(1-2):75-84. doi: 10.1089/ten.TEA.2014.0089. Epub 2014 Sep 12.


The impact of preoperative serum anti-TNFα therapy levels on early postoperative outcomes in inflammatory bowel disease surgery.

Lau C, Dubinsky M, Melmed G, Vasiliauskas E, Berel D, McGovern D, Ippoliti A, Shih D, Targan S, Fleshner P.

Ann Surg. 2015 Mar;261(3):487-96. doi: 10.1097/SLA.0000000000000757.


Antibiotics for Treatment of Clostridium difficile Infection in Hospitalized Patients with Inflammatory Bowel Disease.

Horton HA, Dezfoli S, Berel D, Hirsch J, Ippoliti A, McGovern D, Kaur M, Shih D, Dubinsky M, Targan SR, Fleshner P, Vasiliauskas EA, Grein J, Murthy R, Melmed GY.

Antimicrob Agents Chemother. 2014 Sep;58(9):5054-9. doi: 10.1128/AAC.02606-13. Epub 2014 Jun 9.


Elevated serum anti-flagellin antibodies implicate subclinical bowel inflammation in ankylosing spondylitis: an observational study.

Wallis D, Asaduzzaman A, Weisman M, Haroon N, Anton A, McGovern D, Targan S, Inman R.

Arthritis Res Ther. 2013 Oct 26;15(5):R166. doi: 10.1186/ar4350.


Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project.

Cleynen I, González JR, Figueroa C, Franke A, McGovern D, Bortlík M, Crusius BJ, Vecchi M, Artieda M, Szczypiorska M, Bethge J, Arteta D, Ayala E, Danese S, van Hogezand RA, Panés J, Peña SA, Lukas M, Jewell DP, Schreiber S, Vermeire S, Sans M.

Gut. 2013 Nov;62(11):1556-65. doi: 10.1136/gutjnl-2011-300777. Epub 2012 Dec 21.


Does preoperative immunosuppression influence unplanned hospital readmission after surgery in patients with Crohn's disease?

White EC, Melmed GY, Vasiliauskas E, Dubinsky M, Ippoliti A, McGovern D, Targan S, Fleshner P.

Dis Colon Rectum. 2012 May;55(5):563-8. doi: 10.1097/DCR.0b013e3182468961.


Surgical outcome of ileal pouch-anal anastomosis when used intentionally for well-defined Crohn's disease.

Le Q, Melmed G, Dubinsky M, McGovern D, Vasiliauskas EA, Murrell Z, Ippoliti A, Shih D, Kaur M, Targan S, Fleshner P.

Inflamm Bowel Dis. 2013 Jan;19(1):30-6. doi: 10.1002/ibd.22955.


Host-microbe relationships in inflammatory bowel disease detected by bacterial and metaproteomic analysis of the mucosal-luminal interface.

Presley LL, Ye J, Li X, Leblanc J, Zhang Z, Ruegger PM, Allard J, McGovern D, Ippoliti A, Roth B, Cui X, Jeske DR, Elashoff D, Goodglick L, Braun J, Borneman J.

Inflamm Bowel Dis. 2012 Mar;18(3):409-17. doi: 10.1002/ibd.21793. Epub 2011 Jun 22.


The genetic basis of spondyloarthritis: SPARTAN/IGAS 2009.

Evans DM, Reveille JD, Brown MA, Chandran V, Gladman DD, Martin TM, McGovern D, Wordsworth P, Inman RD.

J Rheumatol. 2010 Dec;37(12):2626-31. doi: 10.3899/jrheum.100892. Erratum in: J Rheumatol. 2011 Apr;38(4):788.

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