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Cross-species comparisons of host genetic associations with the microbiome.

Goodrich JK, Davenport ER, Waters JL, Clark AG, Ley RE.

Science. 2016 Apr 29;352(6285):532-5. doi: 10.1126/science.aad9379. Review.


Erratum to: signatures of early frailty in the gut microbiota.

Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ.

Genome Med. 2016 Feb 17;8(1):21. doi: 10.1186/s13073-016-0275-2. No abstract available.


Gut microbiota in 2015: Prevotella in the gut: choose carefully.

Ley RE.

Nat Rev Gastroenterol Hepatol. 2016 Feb 1;13(2):69-70. doi: 10.1038/nrgastro.2016.4. No abstract available.


Signatures of early frailty in the gut microbiota.

Jackson M, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ.

Genome Med. 2016 Jan 29;8(1):8. doi: 10.1186/s13073-016-0262-7.


Methane Emission in a Specific Riparian-Zone Sediment Decreased with Bioelectrochemical Manipulation and Corresponded to the Microbial Community Dynamics.

Friedman ES, McPhillips LE, Werner JJ, Poole AC, Ley RE, Walter MT, Angenent LT.

Front Microbiol. 2016 Jan 11;6:1523. doi: 10.3389/fmicb.2015.01523. eCollection 2015.


Proton pump inhibitors alter the composition of the gut microbiota.

Jackson MA, Goodrich JK, Maxan ME, Freedberg DE, Abrams JA, Poole AC, Sutter JL, Welter D, Ley RE, Bell JT, Spector TD, Steves CJ.

Gut. 2016 May;65(5):749-56. doi: 10.1136/gutjnl-2015-310861. Epub 2015 Dec 30.


Novel Rhizosphere Soil Alleles for the Enzyme 1-Aminocyclopropane-1-Carboxylate Deaminase Queried for Function with an In Vivo Competition Assay.

Jin Z, Di Rienzi SC, Janzon A, Werner JJ, Angenent LT, Dangl JL, Fowler DM, Ley RE.

Appl Environ Microbiol. 2015 Dec 4;82(4):1050-9. doi: 10.1128/AEM.03074-15.


Epithelial Sel1L is required for the maintenance of intestinal homeostasis.

Sun S, Lourie R, Cohen SB, Ji Y, Goodrich JK, Poole AC, Ley RE, Denkers EY, McGuckin MA, Long Q, Duhamel GE, Simpson KW, Qi L.

Mol Biol Cell. 2016 Feb 1;27(3):483-90. doi: 10.1091/mbc.E15-10-0724. Epub 2015 Dec 2.


Potential applications of next generation DNA sequencing of 16S rRNA gene amplicons in microbial water quality monitoring.

Vierheilig J, Savio D, Ley RE, Mach RL, Farnleitner AH, Reischer GH.

Water Sci Technol. 2015;72(11):1962-72. doi: 10.2166/wst.2015.407.


TGR5 contributes to glucoregulatory improvements after vertical sleeve gastrectomy in mice.

McGavigan AK, Garibay D, Henseler ZM, Chen J, Bettaieb A, Haj FG, Ley RE, Chouinard ML, Cummings BP.

Gut. 2015 Oct 28. pii: gutjnl-2015-309871. doi: 10.1136/gutjnl-2015-309871. [Epub ahead of print]


Host genetic variation impacts microbiome composition across human body sites.

Blekhman R, Goodrich JK, Huang K, Sun Q, Bukowski R, Bell JT, Spector TD, Keinan A, Ley RE, Gevers D, Clark AG.

Genome Biol. 2015 Sep 15;16:191. doi: 10.1186/s13059-015-0759-1.


Gut-Microbiota-Metabolite Axis in Early Renal Function Decline.

Barrios C, Beaumont M, Pallister T, Villar J, Goodrich JK, Clark A, Pascual J, Ley RE, Spector TD, Bell JT, Menni C.

PLoS One. 2015 Aug 4;10(8):e0134311. doi: 10.1371/journal.pone.0134311. eCollection 2015.


Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.

Chassaing B, Koren O, Goodrich JK, Poole AC, Srinivasan S, Ley RE, Gewirtz AT.

Nature. 2015 Mar 5;519(7541):92-6. doi: 10.1038/nature14232. Epub 2015 Feb 25.


The gene-microbe link.

Ley RE.

Nature. 2015 Feb 26;518(7540):S7. doi: 10.1038/518S7a. No abstract available.


Gut microbiota as an epigenetic regulator: pilot study based on whole-genome methylation analysis.

Kumar H, Lund R, Laiho A, Lundelin K, Ley RE, Isolauri E, Salminen S.

MBio. 2014 Dec 16;5(6). pii: e02113-14. doi: 10.1128/mBio.02113-14.


Human genetics shape the gut microbiome.

Goodrich JK, Waters JL, Poole AC, Sutter JL, Koren O, Blekhman R, Beaumont M, Van Treuren W, Knight R, Bell JT, Spector TD, Clark AG, Ley RE.

Cell. 2014 Nov 6;159(4):789-99. doi: 10.1016/j.cell.2014.09.053.


Selection on soil microbiomes reveals reproducible impacts on plant function.

Panke-Buisse K, Poole AC, Goodrich JK, Ley RE, Kao-Kniffin J.

ISME J. 2015 Mar 17;9(4):980-9. doi: 10.1038/ismej.2014.196.


Advancing the microbiome research community.

Huttenhower C, Knight R, Brown CT, Caporaso JG, Clemente JC, Gevers D, Franzosa EA, Kelley ST, Knights D, Ley RE, Mahurkar A, Ravel J; Scientists for Advancement of Microbiome Research, White O.

Cell. 2014 Oct 9;159(2):227-30. doi: 10.1016/j.cell.2014.09.022.


Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome's potential to cause inflammation.

Leifer CA, McConkey C, Li S, Chassaing B, Gewirtz AT, Ley RE.

Immunol Lett. 2014 Dec;162(2 Pt A):3-9. doi: 10.1016/j.imlet.2014.07.017. Epub 2014 Oct 2. Review.


Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice.

Chassaing B, Ley RE, Gewirtz AT.

Gastroenterology. 2014 Dec;147(6):1363-77.e17. doi: 10.1053/j.gastro.2014.08.033. Epub 2014 Aug 27.

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