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Results: 1 to 20 of 70

1.

Therapeutic effects of melatonin receptor agonists on sleep and comorbid disorders.

Laudon M, Frydman-Marom A.

Int J Mol Sci. 2014 Sep 9;15(9):15924-50. doi: 10.3390/ijms150915924. Review.

PMID:
25207602
[PubMed - in process]
Free PMC Article
2.

Melatonin receptors in diabetes: A potential new therapeutical target?

She M, Laudon M, Yin W.

Eur J Pharmacol. 2014 Aug 24. pii: S0014-2999(14)00617-7. doi: 10.1016/j.ejphar.2014.08.012. [Epub ahead of print]

PMID:
25160745
[PubMed - as supplied by publisher]
3.

Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.

Wade AG, Farmer M, Harari G, Fund N, Laudon M, Nir T, Frydman-Marom A, Zisapel N.

Clin Interv Aging. 2014 Jun 18;9:947-61. doi: 10.2147/CIA.S65625. eCollection 2014.

PMID:
24971004
[PubMed - in process]
Free PMC Article
4.

Melatonin rescues 3T3-L1 adipocytes from FFA-induced insulin resistance by inhibiting phosphorylation of IRS-1 on Ser307.

She M, Hou H, Wang Z, Zhang C, Laudon M, Yin W.

Biochimie. 2014 Aug;103:126-30. doi: 10.1016/j.biochi.2014.05.001. Epub 2014 May 15.

PMID:
24846082
[PubMed - in process]
5.

Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain.

Liu YY, Yin D, Chen L, Qu WM, Chen CR, Laudon M, Cheng NN, Urade Y, Huang ZL.

Psychopharmacology (Berl). 2014 Oct;231(20):3973-85. doi: 10.1007/s00213-014-3530-5. Epub 2014 Apr 4.

PMID:
24700387
[PubMed - in process]
6.

Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.

Chen C, Fichna J, Laudon M, Storr M.

World J Gastroenterol. 2014 Feb 7;20(5):1298-304. doi: 10.3748/wjg.v20.i5.1298.

PMID:
24574803
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Piromelatine, a novel melatonin receptor agonist, stabilizes metabolic profiles and ameliorates insulin resistance in chronic sleep restricted rats.

She M, Hu X, Su Z, Zhang C, Yang S, Ding L, Laudon M, Yin W.

Eur J Pharmacol. 2014 Mar 15;727:60-5. doi: 10.1016/j.ejphar.2014.01.037. Epub 2014 Jan 30.

PMID:
24486392
[PubMed - in process]
8.

Blood pressure reducing effects of piromelatine and melatonin in spontaneously hypertensive rats.

Huang L, Zhang C, Hou Y, Laudon M, She M, Yang S, Ding L, Wang H, Wang Z, He P, Yin W.

Eur Rev Med Pharmacol Sci. 2013 Sep;17(18):2449-56.

PMID:
24089222
[PubMed - indexed for MEDLINE]
Free Article
9.

Piromelatine decreases triglyceride accumulation in insulin resistant 3T3-L1 adipocytes: role of ATGL and HSL.

Wang PP, She MH, He PP, Chen WJ, Laudon M, Xu XX, Yin WD.

Biochimie. 2013 Aug;95(8):1650-4. doi: 10.1016/j.biochi.2013.05.005. Epub 2013 May 23.

PMID:
23707538
[PubMed - indexed for MEDLINE]
10.

Neu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammation.

Thatcher TH, Hsiao HM, Pinner E, Laudon M, Pollock SJ, Sime PJ, Phipps RP.

Am J Physiol Lung Cell Mol Physiol. 2013 Jul 15;305(2):L165-74. doi: 10.1152/ajplung.00036.2013. Epub 2013 May 17.

PMID:
23686858
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A novel melatonin agonist Neu-P11 facilitates memory performance and improves cognitive impairment in a rat model of Alzheimer' disease.

He P, Ouyang X, Zhou S, Yin W, Tang C, Laudon M, Tian S.

Horm Behav. 2013 Jun;64(1):1-7. doi: 10.1016/j.yhbeh.2013.04.009. Epub 2013 May 4.

PMID:
23651610
[PubMed - indexed for MEDLINE]
12.

Cardiovascular effects of melatonin receptor agonists.

Paulis L, Simko F, Laudon M.

Expert Opin Investig Drugs. 2012 Nov;21(11):1661-78. doi: 10.1517/13543784.2012.714771. Epub 2012 Aug 23. Review.

PMID:
22916799
[PubMed - indexed for MEDLINE]
13.

Effect of melatonin on nocturnal blood pressure: meta-analysis of randomized controlled trials.

Grossman E, Laudon M, Zisapel N.

Vasc Health Risk Manag. 2011;7:577-84. doi: 10.2147/VHRM.S24603. Epub 2011 Sep 15. Review.

PMID:
21966222
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Efficacy and safety of prolonged-release melatonin in insomnia patients with diabetes: a randomized, double-blind, crossover study.

Garfinkel D, Zorin M, Wainstein J, Matas Z, Laudon M, Zisapel N.

Diabetes Metab Syndr Obes. 2011;4:307-13. doi: 10.2147/DMSO.S23904. Epub 2011 Aug 2.

PMID:
21887103
[PubMed]
Free PMC Article
15.

Prolonged-release melatonin for insomnia - an open-label long-term study of efficacy, safety, and withdrawal.

Lemoine P, Garfinkel D, Laudon M, Nir T, Zisapel N.

Ther Clin Risk Manag. 2011;7:301-11. doi: 10.2147/TCRM.S23036. Epub 2011 Jul 26.

PMID:
21845053
[PubMed]
Free PMC Article
16.

Prolonged-release melatonin for children with neurodevelopmental disorders.

De Leersnyder H, Zisapel N, Laudon M.

Pediatr Neurol. 2011 Jul;45(1):23-6. doi: 10.1016/j.pediatrneurol.2011.02.001.

PMID:
21723455
[PubMed - indexed for MEDLINE]
17.

Prolonged release melatonin in the treatment of primary insomnia: evaluation of the age cut-off for short- and long-term response.

Wade AG, Crawford G, Ford I, McConnachie A, Nir T, Laudon M, Zisapel N.

Curr Med Res Opin. 2011 Jan;27(1):87-98. doi: 10.1185/03007995.2010.537317. Epub 2010 Nov 24.

PMID:
21091391
[PubMed - indexed for MEDLINE]
18.

Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.

Wade AG, Ford I, Crawford G, McConnachie A, Nir T, Laudon M, Zisapel N.

BMC Med. 2010 Aug 16;8:51. doi: 10.1186/1741-7015-8-51.

PMID:
20712869
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Antidepressant- and anxiolytic effects of the novel melatonin agonist Neu-P11 in rodent models.

Tian SW, Laudon M, Han L, Gao J, Huang FL, Yang YF, Deng HF.

Acta Pharmacol Sin. 2010 Jul;31(7):775-83. doi: 10.1038/aps.2010.80. Epub 2010 Jun 28.

PMID:
20581849
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

NEU-P11, a novel melatonin agonist, inhibits weight gain and improves insulin sensitivity in high-fat/high-sucrose-fed rats.

She M, Deng X, Guo Z, Laudon M, Hu Z, Liao D, Hu X, Luo Y, Shen Q, Su Z, Yin W.

Pharmacol Res. 2009 Apr;59(4):248-53. doi: 10.1016/j.phrs.2009.01.005. Epub 2009 Jan 24.

PMID:
19429466
[PubMed - indexed for MEDLINE]

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