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Results: 19

1.

Mitochondrial Oxidative Phosphorylation Transcriptome Alterations in Human Amyotrophic Lateral Sclerosis Spinal Cord and Blood.

Ladd AC, Keeney PM, Govind MM, Bennett JP Jr.

Neuromolecular Med. 2014 Aug 1. [Epub ahead of print]

PMID:
25081190
[PubMed - as supplied by publisher]
2.

Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimer's disease hippocampi.

Rice AC, Keeney PM, Algarzae NK, Ladd AC, Thomas RR, Bennett JP Jr.

J Alzheimers Dis. 2014;40(2):319-30. doi: 10.3233/JAD-131715.

PMID:
24448779
[PubMed - in process]
3.

Impaired complex-I mitochondrial biogenesis in Parkinson disease frontal cortex.

Thomas RR, Keeney PM, Bennett JP.

J Parkinsons Dis. 2012;2(1):67-76. doi: 10.3233/JPD-2012-11074.

PMID:
23939409
[PubMed - indexed for MEDLINE]
4.

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions.

Keeney PM, Bennett JP Jr.

Mol Neurodegener. 2010 May 26;5:21. doi: 10.1186/1750-1326-5-21.

PMID:
20504367
[PubMed]
Free PMC Article
5.

Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships.

Keeney PM, Dunham LD, Quigley CK, Morton SL, Bergquist KE, Bennett JP Jr.

Exp Neurol. 2009 Dec;220(2):374-82. doi: 10.1016/j.expneurol.2009.09.025. Epub 2009 Oct 6.

PMID:
19815014
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP Jr.

Hum Gene Ther. 2009 Aug;20(8):897-907. doi: 10.1089/hum.2009.023.

PMID:
19374590
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells.

Borland MK, Trimmer PA, Rubinstein JD, Keeney PM, Mohanakumar K, Liu L, Bennett JP Jr.

Mol Neurodegener. 2008 Dec 29;3:21. doi: 10.1186/1750-1326-3-21.

PMID:
19114014
[PubMed]
Free PMC Article
9.

Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues.

Borland MK, Mohanakumar KP, Rubinstein JD, Keeney PM, Xie J, Capaldi R, Dunham LD, Trimmer PA, Bennett JP Jr.

Biochim Biophys Acta. 2009 Jan;1792(1):68-74. doi: 10.1016/j.bbadis.2008.09.014. Epub 2008 Oct 10.

PMID:
18973805
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

Keeney PM, Xie J, Capaldi RA, Bennett JP Jr.

J Neurosci. 2006 May 10;26(19):5256-64.

PMID:
16687518
[PubMed - indexed for MEDLINE]
Free Article
11.

Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies.

Trimmer PA, Borland MK, Keeney PM, Bennett JP Jr, Parker WD Jr.

J Neurochem. 2004 Feb;88(4):800-12.

PMID:
14756800
[PubMed - indexed for MEDLINE]
12.

Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture.

Trimmer PA, Keeney PM, Borland MK, Simon FA, Almeida J, Swerdlow RH, Parks JP, Parker WD Jr, Bennett JP Jr.

Neurobiol Dis. 2004 Feb;15(1):29-39.

PMID:
14751768
[PubMed - indexed for MEDLINE]
13.

Neurotoxic nitric oxide rapidly depolarizes and permeabilizes mitochondria by dynamically opening the mitochondrial transition pore.

Kindler DD, Thiffault C, Solenski NJ, Dennis J, Kostecki V, Jenkins R, Keeney PM, Bennett JP Jr.

Mol Cell Neurosci. 2003 Aug;23(4):559-73.

PMID:
12932437
[PubMed - indexed for MEDLINE]
14.

Antibody types and IgG subclasses in paraneoplastic neurological syndromes.

Greenlee JE, Boyden JW, Pingree M, Brashear HR, Clawson SA, Keeney PM.

J Neurol Sci. 2001 Mar 1;184(2):131-7.

PMID:
11239946
[PubMed - indexed for MEDLINE]
15.

Disrupted mitochondrial electron transport function increases expression of anti-apoptotic bcl-2 and bcl-X(L) proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress.

Veech GA, Dennis J, Keeney PM, Fall CP, Swerdlow RH, Parker WD Jr, Bennett JP Jr.

J Neurosci Res. 2000 Sep 15;61(6):693-700.

PMID:
10972966
[PubMed - indexed for MEDLINE]
16.

Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways.

Khan SM, Cassarino DS, Abramova NN, Keeney PM, Borland MK, Trimmer PA, Krebs CT, Bennett JC, Parks JK, Swerdlow RH, Parker WD Jr, Bennett JP Jr.

Ann Neurol. 2000 Aug;48(2):148-55.

PMID:
10939564
[PubMed - indexed for MEDLINE]
17.

Localization of antibody in the central nervous system of a patient with paraneoplastic encephalomyeloneuritis.

Brashear HR, Caccamo DV, Heck A, Keeney PM.

Neurology. 1991 Oct;41(10):1583-7.

PMID:
1656326
[PubMed - indexed for MEDLINE]
18.

Immunoenzymatic labelling of JC papovavirus T antigen in brains of patients with progressive multifocal leukoencephalopathy.

Greenlee JE, Keeney PM.

Acta Neuropathol. 1986;71(1-2):150-3.

PMID:
3022533
[PubMed - indexed for MEDLINE]

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