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Results: 1 to 20 of 474

1.

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation.

Shinde V, Klima S, Sureshkumar PS, Meganathan K, Jagtap S, Rempel E, Rahnenführer J, Hengstler JG, Waldmann T, Hescheler J, Leist M, Sachinidis A.

J Vis Exp. 2015 Jun 17;(100). doi: 10.3791/52333.

PMID:
26132533
2.

Low concentrations of ethanol but not of dimethyl sulfoxide (DMSO) impair reciprocal retinal signal transduction.

Siapich SA, Akhtar I, Hescheler J, Schneider T, Lüke M.

Graefes Arch Clin Exp Ophthalmol. 2015 Jun 25. [Epub ahead of print]

PMID:
26104874
3.

Docosahexaenoic acid alters Gsα localization in lipid raft and potentiates adenylate cyclase.

Zhu Z, Tan Z, Li Y, Luo H, Hu X, Tang M, Hescheler J, Mu Y, Zhang L.

Nutrition. 2015 Jul-Aug;31(7-8):1025-30. doi: 10.1016/j.nut.2015.02.012. Epub 2015 Mar 17.

PMID:
26059378
4.

Calcium Imaging in Pluripotent Stem Cell-Derived Cardiac Myocytes.

Walter A, Šarić T, Hescheler J, Papadopoulos S.

Methods Mol Biol. 2015 May 30. [Epub ahead of print]

PMID:
26025623
5.

Ascorbic Acid-Induced Cardiac Differentiation of Murine Pluripotent Stem Cells: Transcriptional Profiling and Effect of a Small Molecule Synergist of Wnt/β-Catenin Signaling Pathway.

Ivanyuk D, Budash G, Zheng Y, Gaspar JA, Chaudhari U, Fatima A, Bahmanpour S, Grin VK, Popandopulo AG, Sachinidis A, Hescheler J, Šarić T.

Cell Physiol Biochem. 2015;36(2):810-30. doi: 10.1159/000430140. Epub 2015 May 22.

PMID:
26021268
6.

Effects of synthetic neural adhesion molecule mimetic peptides and related proteins on the cardiomyogenic differentiation of mouse embryonic stem cells.

Xu R, Srinivasan SP, Sureshkumar P, Nembo EN, Schäfer C, Semmler J, Matzkies M, Albrechtsen M, Hescheler J, Nguemo F.

Cell Physiol Biochem. 2015;35(6):2437-50. doi: 10.1159/000374044. Epub 2015 Apr 24.

PMID:
25967873
7.

Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells.

Meganathan K, Jagtap S, Srinivasan SP, Wagh V, Hescheler J, Hengstler J, Leist M, Sachinidis A.

Cell Death Dis. 2015 May 7;6:e1756. doi: 10.1038/cddis.2015.121.

PMID:
25950486
8.

Chromosome tracking in fused cells by single nucleotide polymorphisms.

Fatima A, Hescheler J, Šaric T.

Methods Mol Biol. 2015;1313:95-106. doi: 10.1007/978-1-4939-2703-6_6.

PMID:
25947658
9.

Excitation-contraction coupling in zebrafish ventricular myocardium is regulated by trans-sarcolemmal Ca2+ influx and sarcoplasmic reticulum Ca2+ release.

Haustein M, Hannes T, Trieschmann J, Verhaegh R, Köster A, Hescheler J, Brockmeier K, Adelmann R, Khalil M.

PLoS One. 2015 May 4;10(5):e0125654. doi: 10.1371/journal.pone.0125654. eCollection 2015.

10.

Susceptibility of murine induced pluripotent stem cell-derived cardiomyocytes to hypoxia and nutrient deprivation.

Brodarac A, Šarić T, Oberwallner B, Mahmoodzadeh S, Neef K, Albrecht J, Burkert K, Oliverio M, Nguemo F, Choi YH, Neiss WF, Morano I, Hescheler J, Stamm C.

Stem Cell Res Ther. 2015 Apr 23;6:83. doi: 10.1186/s13287-015-0057-6.

11.

Traditional Chinese medicine baicalin suppresses mESCs proliferation through inhibition of miR-294 expression.

Wang J, Masika J, Zhou J, Wang J, Zhu M, Luo H, Hu X, Zhang L, Tang M, Gao L, Hescheler J, Liang H.

Cell Physiol Biochem. 2015;35(5):1868-76. doi: 10.1159/000373997. Epub 2015 Mar 26.

PMID:
25871338
12.

Voltage-gated calcium channels: Determinants of channel function and modulation by inorganic cations.

Neumaier F, Dibué-Adjei M, Hescheler J, Schneider T.

Prog Neurobiol. 2015 Jun;129:1-36. doi: 10.1016/j.pneurobio.2014.12.003. Epub 2015 Mar 25. Review.

PMID:
25817891
13.

Regionally diverse mitochondrial calcium signaling regulates spontaneous pacing in developing cardiomyocytes.

Zhang XH, Wei H, Šarić T, Hescheler J, Cleemann L, Morad M.

Cell Calcium. 2015 May;57(5-6):321-36. doi: 10.1016/j.ceca.2015.02.003. Epub 2015 Feb 18.

PMID:
25746147
14.

Stem cells and differentiation--a synoptic review of patents granted since 2009.

Sureshkumar P, Srinivasan SP, Natarajan K, Gaspar JA, Hescheler J, Sachinidis A.

Expert Opin Ther Pat. 2015 Jun;25(6):663-73. doi: 10.1517/13543776.2015.1021334. Epub 2015 Mar 2.

PMID:
25732569
15.

In vitro chronotropic effects of Erythrina senegalensis DC (Fabaceae) aqueous extract on mouse heart slice and pluripotent stem cell-derived cardiomyocytes.

Nembo EN, Atsamo AD, Nguelefack TB, Kamanyi A, Hescheler J, Nguemo F.

J Ethnopharmacol. 2015 May 13;165:163-72. doi: 10.1016/j.jep.2015.02.002. Epub 2015 Feb 11.

PMID:
25680843
16.

Stem cell-derived systems in toxicology assessment.

Suter-Dick L, Alves PM, Blaauboer BJ, Bremm KD, Brito C, Coecke S, Flick B, Fowler P, Hescheler J, Ingelman-Sundberg M, Jennings P, Kelm JM, Manou I, Mistry P, Moretto A, Roth A, Stedman D, van de Water B, Beilmann M.

Stem Cells Dev. 2015 Jun 1;24(11):1284-96. doi: 10.1089/scd.2014.0540. Epub 2015 Mar 31.

PMID:
25675366
17.

Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development.

Meganathan K, Sotiriadou I, Natarajan K, Hescheler J, Sachinidis A.

Int J Cardiol. 2015 Mar 15;183:117-28. doi: 10.1016/j.ijcard.2015.01.049. Epub 2015 Jan 27. Review.

PMID:
25662074
18.

Diethyldithiocarbamate-mediated zinc ion chelation reveals role of Cav2.3 channels in glucagon secretion.

Drobinskaya I, Neumaier F, Pereverzev A, Hescheler J, Schneider T.

Biochim Biophys Acta. 2015 May;1853(5):953-64. doi: 10.1016/j.bbamcr.2015.01.001. Epub 2015 Jan 17.

PMID:
25603538
19.

Electrophysiological characteristics of embryonic stem cell-derived cardiomyocytes are cell line-dependent.

Hannes T, Wolff M, Doss MX, Pfannkuche K, Haustein M, Müller-Ehmsen J, Sachinidis A, Hescheler J, Khalil M, Halbach M.

Cell Physiol Biochem. 2015;35(1):305-14. doi: 10.1159/000369697. Epub 2015 Jan 10.

PMID:
25591772
20.

diXa: a data infrastructure for chemical safety assessment.

Hendrickx DM, Aerts HJ, Caiment F, Clark D, Ebbels TM, Evelo CT, Gmuender H, Hebels DG, Herwig R, Hescheler J, Jennen DG, Jetten MJ, Kanterakis S, Keun HC, Matser V, Overington JP, Pilicheva E, Sarkans U, Segura-Lepe MP, Sotiriadou I, Wittenberger T, Wittwehr C, Zanzi A, Kleinjans JC.

Bioinformatics. 2015 May 1;31(9):1505-7. doi: 10.1093/bioinformatics/btu827. Epub 2014 Dec 12.

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