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Items: 1 to 20 of 128

1.

Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein.

Renner M, Bertinelli M, Leyrat C, Paesen GC, Saraiva de Oliveira LF, Huiskonen JT, Grimes JM.

Elife. 2016 Feb 15;5. pii: e12627. doi: 10.7554/eLife.12627.

2.

An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1.

Baskaran Y, Ang KC, Anekal PV, Chan WL, Grimes JM, Manser E, Robinson RC.

Nat Commun. 2015 Nov 26;6:8681. doi: 10.1038/ncomms9681.

3.

X-ray structure and activities of an essential Mononegavirales L-protein domain.

Paesen GC, Collet A, Sallamand C, Debart F, Vasseur JJ, Canard B, Decroly E, Grimes JM.

Nat Commun. 2015 Nov 9;6:8749. doi: 10.1038/ncomms9749.

4.

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.

Hengrung N, El Omari K, Serna Martin I, Vreede FT, Cusack S, Rambo RP, Vonrhein C, Bricogne G, Stuart DI, Grimes JM, Fodor E.

Nature. 2015 Nov 5;527(7576):114-7. doi: 10.1038/nature15525. Epub 2015 Oct 26.

5.

Structure Elucidation of Coxsackievirus A16 in Complex with GPP3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.

De Colibus L, Wang X, Tijsma A, Neyts J, Spyrou JA, Ren J, Grimes JM, Puerstinger G, Leyssen P, Fry EE, Rao Z, Stuart DI.

PLoS Pathog. 2015 Oct 20;11(10):e1005165. doi: 10.1371/journal.ppat.1005165. eCollection 2015 Oct.

6.

Calcium-controlled conformational choreography in the N-terminal half of adseverin.

Chumnarnsilpa S, Robinson RC, Grimes JM, Leyrat C.

Nat Commun. 2015 Sep 14;6:8254. doi: 10.1038/ncomms9254.

7.

Corrigendum: A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus.

Dejnirattisai W, Wongwiwat W, Supasa S, Zhang X, Dai X, Rouvinsky A, Jumnainsong A, Edwards C, Quyen NT, Duangchinda T, Grimes JM, Tsai WY, Lai CY, Wang WK, Malasit P, Farrar J, Simmons CP, Zhou ZH, Rey FA, Mongkolsapaya J, Screaton GR.

Nat Immunol. 2015 Jul;16(7):785. doi: 10.1038/ni0715-785a. No abstract available.

PMID:
26086146
8.

A revised partiality model and post-refinement algorithm for X-ray free-electron laser data.

Ginn HM, Brewster AS, Hattne J, Evans G, Wagner A, Grimes JM, Sauter NK, Sutton G, Stuart DI.

Acta Crystallogr D Biol Crystallogr. 2015 Jun;71(Pt 6):1400-10. doi: 10.1107/S1399004715006902. Epub 2015 May 23.

9.

Corrigendum: A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus.

Dejnirattisai W, Wongwiwat W, Supasa S, Zhang X, Dai X, Rouvinsky A, Jumnainsong A, Edwards C, Quyen NT, Duangchinda T, Grimes JM, Tsai WY, Lai CY, Wang WK, Malasit P, Farrar J, Simmons CP, Zhou ZH, Rey FA, Mongkolsapaya J, Screaton GR.

Nat Immunol. 2015 May;16(5):544. doi: 10.1038/ni0515-544b. No abstract available.

PMID:
25898199
10.

Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.

Ginn HM, Messerschmidt M, Ji X, Zhang H, Axford D, Gildea RJ, Winter G, Brewster AS, Hattne J, Wagner A, Grimes JM, Evans G, Sauter NK, Sutton G, Stuart DI.

Nat Commun. 2015 Mar 9;6:6435. doi: 10.1038/ncomms7435.

11.

Yersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization.

Lee WL, Grimes JM, Robinson RC.

Nat Struct Mol Biol. 2015 Mar;22(3):248-55. doi: 10.1038/nsmb.2964. Epub 2015 Feb 9.

12.

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus.

Dejnirattisai W, Wongwiwat W, Supasa S, Zhang X, Dai X, Rouvinski A, Jumnainsong A, Edwards C, Quyen NT, Duangchinda T, Grimes JM, Tsai WY, Lai CY, Wang WK, Malasit P, Farrar J, Simmons CP, Zhou ZH, Rey FA, Mongkolsapaya J, Screaton GR.

Nat Immunol. 2015 Feb;16(2):170-7. doi: 10.1038/ni.3058. Epub 2014 Dec 15. Erratum in: Nat Immunol. 2015 Jul;16(7):785. Nat Immunol. 2015 May;16(5):544.

13.

Structural basis of thymosin-β4/profilin exchange leading to actin filament polymerization.

Xue B, Leyrat C, Grimes JM, Robinson RC.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4596-605. doi: 10.1073/pnas.1412271111. Epub 2014 Oct 13.

14.

SynchLink: an iOS app for ISPyB.

Ginn HM, Mostefaoui GK, Levik KE, Grimes JM, Walsh MA, Ashton AW, Stuart DI.

J Appl Crystallogr. 2014 Sep 4;47(Pt 5):1781-1783. eCollection 2014 Oct 1.

15.

Unexpected structure for the N-terminal domain of hepatitis C virus envelope glycoprotein E1.

El Omari K, Iourin O, Kadlec J, Sutton G, Harlos K, Grimes JM, Stuart DI.

Nat Commun. 2014 Sep 16;5:4874. doi: 10.1038/ncomms5874.

16.

Pushing the limits of sulfur SAD phasing: de novo structure solution of the N-terminal domain of the ectodomain of HCV E1.

El Omari K, Iourin O, Kadlec J, Fearn R, Hall DR, Harlos K, Grimes JM, Stuart DI.

Acta Crystallogr D Biol Crystallogr. 2014 Aug;70(Pt 8):2197-203. doi: 10.1107/S139900471401339X. Epub 2014 Jul 25.

17.

Structural insights into the human metapneumovirus glycoprotein ectodomain.

Leyrat C, Paesen GC, Charleston J, Renner M, Grimes JM.

J Virol. 2014 Oct;88(19):11611-6. doi: 10.1128/JVI.01726-14. Epub 2014 Jul 16.

18.

Drastic changes in conformational dynamics of the antiterminator M2-1 regulate transcription efficiency in Pneumovirinae.

Leyrat C, Renner M, Harlos K, Huiskonen JT, Grimes JM.

Elife. 2014 May 19;3:e02674. doi: 10.7554/eLife.02674.

19.

Structure and self-assembly of the calcium binding matrix protein of human metapneumovirus.

Leyrat C, Renner M, Harlos K, Huiskonen JT, Grimes JM.

Structure. 2014 Jan 7;22(1):136-48. doi: 10.1016/j.str.2013.10.013. Epub 2013 Dec 5.

20.

Solution and crystallographic structures of the central region of the phosphoprotein from human metapneumovirus.

Leyrat C, Renner M, Harlos K, Grimes JM.

PLoS One. 2013 Nov 4;8(11):e80371. doi: 10.1371/journal.pone.0080371. eCollection 2013.

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