Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 73


Cytosolic Ca2+ buffering determines the intra-SR Ca2+ concentration at which cardiac Ca2+ sparks terminate.

Bovo E, Mazurek SR, Fill M, Zima AV.

Cell Calcium. 2015 Jun 10. pii: S0143-4160(15)00097-4. doi: 10.1016/j.ceca.2015.06.002. [Epub ahead of print]


The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice.

Zhang J, Chen B, Zhong X, Mi T, Guo A, Zhou Q, Tan Z, Wu G, Chen AW, Fill M, Song LS, Chen SR.

Biochem J. 2014 Jul 1;461(1):99-106. doi: 10.1042/BJ20140126.


The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias.

Chen W, Wang R, Chen B, Zhong X, Kong H, Bai Y, Zhou Q, Xie C, Zhang J, Guo A, Tian X, Jones PP, O'Mara ML, Liu Y, Mi T, Zhang L, Bolstad J, Semeniuk L, Cheng H, Zhang J, Chen J, Tieleman DP, Gillis AM, Duff HJ, Fill M, Song LS, Chen SR.

Nat Med. 2014 Feb;20(2):184-92. doi: 10.1038/nm.3440. Epub 2014 Jan 19.


Sarcoplasmic reticulum K(+) (TRIC) channel does not carry essential countercurrent during Ca(2+) release.

Guo T, Nani A, Shonts S, Perryman M, Chen H, Shannon T, Gillespie D, Fill M.

Biophys J. 2013 Sep 3;105(5):1151-60. doi: 10.1016/j.bpj.2013.07.042.


Potential role of cardiac calsequestrin in the lethal arrhythmic effects of cocaine.

Sanchez EJ, Hayes RP, Barr JT, Lewis KM, Webb BN, Subramanian AK, Nissen MS, Jones JP, Shelden EA, Sorg BA, Fill M, Schenk JO, Kang C.

Drug Alcohol Depend. 2013 Dec 1;133(2):344-51. doi: 10.1016/j.drugalcdep.2013.06.012. Epub 2013 Jul 19.


Mechanism of calsequestrin regulation of single cardiac ryanodine receptor in normal and pathological conditions.

Chen H, Valle G, Furlan S, Nani A, Gyorke S, Fill M, Volpe P.

J Gen Physiol. 2013 Aug;142(2):127-36. doi: 10.1085/jgp.201311022. Epub 2013 Jul 15.


Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.

Brunello L, Slabaugh JL, Radwanski PB, Ho HT, Belevych AE, Lou Q, Chen H, Napolitano C, Lodola F, Priori SG, Fedorov VV, Volpe P, Fill M, Janssen PM, Gy├Ârke S.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10312-7. doi: 10.1073/pnas.1300052110. Epub 2013 Jun 3.


Pernicious attrition and inter-RyR2 CICR current control in cardiac muscle.

Gillespie D, Fill M.

J Mol Cell Cardiol. 2013 May;58:53-8. doi: 10.1016/j.yjmcc.2013.01.011. Epub 2013 Jan 28. Review.


Ryanodine receptor current amplitude controls Ca2+ sparks in cardiac muscle.

Guo T, Gillespie D, Fill M.

Circ Res. 2012 Jun 22;111(1):28-36. doi: 10.1161/CIRCRESAHA.112.265652. Epub 2012 May 24.


Is ryanodine receptor a calcium or magnesium channel? Roles of K+ and Mg2+ during Ca2+ release.

Gillespie D, Chen H, Fill M.

Cell Calcium. 2012 Jun;51(6):427-33. doi: 10.1016/j.ceca.2012.02.001. Epub 2012 Mar 3.


Abnormal termination of Ca2+ release is a common defect of RyR2 mutations associated with cardiomyopathies.

Tang Y, Tian X, Wang R, Fill M, Chen SR.

Circ Res. 2012 Mar 30;110(7):968-77. doi: 10.1161/CIRCRESAHA.111.256560. Epub 2012 Feb 28.


Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release.

Zhou Q, Xiao J, Jiang D, Wang R, Vembaiyan K, Wang A, Smith CD, Xie C, Chen W, Zhang J, Tian X, Jones PP, Zhong X, Guo A, Chen H, Zhang L, Zhu W, Yang D, Li X, Chen J, Gillis AM, Duff HJ, Cheng H, Feldman AM, Song LS, Fill M, Back TG, Chen SR.

Nat Med. 2011 Jul 10;17(8):1003-9. doi: 10.1038/nm.2406.


Single ryanodine receptor channel basis of caffeine's action on Ca2+ sparks.

Porta M, Zima AV, Nani A, Diaz-Sylvester PL, Copello JA, Ramos-Franco J, Blatter LA, Fill M.

Biophys J. 2011 Feb 16;100(4):931-8. doi: 10.1016/j.bpj.2011.01.017.


Ryanodol action on calcium sparks in ventricular myocytes.

Ramos-Franco J, Gomez AM, Nani A, Liu Y, Copello JA, Fill M.

Pflugers Arch. 2010 Sep;460(4):767-76. doi: 10.1007/s00424-010-0839-8. Epub 2010 Apr 24.


Flux regulation of cardiac ryanodine receptor channels.

Liu Y, Porta M, Qin J, Ramos J, Nani A, Shannon TR, Fill M.

J Gen Physiol. 2010 Jan;135(1):15-27. doi: 10.1085/jgp.200910273. Epub 2009 Dec 14.


Reinterpreting the anomalous mole fraction effect: the ryanodine receptor case study.

Gillespie D, Giri J, Fill M.

Biophys J. 2009 Oct 21;97(8):2212-21. doi: 10.1016/j.bpj.2009.08.009.


Ryanodine receptor luminal Ca2+ regulation: swapping calsequestrin and channel isoforms.

Qin J, Valle G, Nani A, Chen H, Ramos-Franco J, Nori A, Volpe P, Fill M.

Biophys J. 2009 Oct 7;97(7):1961-70. doi: 10.1016/j.bpj.2009.07.030.


Trifluoperazine: a rynodine receptor agonist.

Qin J, Zima AV, Porta M, Blatter LA, Fill M.

Pflugers Arch. 2009 Aug;458(4):643-51. doi: 10.1007/s00424-009-0658-y. Epub 2009 Mar 11.


Optically pumped 5 microm IV-VI VECSEL with Al-heat spreader.

Rahim M, Felder F, Fill M, Zogg H.

Opt Lett. 2008 Dec 15;33(24):3010-2.


Tricyclic antidepressant amitriptyline alters sarcoplasmic reticulum calcium handling in ventricular myocytes.

Zima AV, Qin J, Fill M, Blatter LA.

Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2008-16. doi: 10.1152/ajpheart.00523.2008. Epub 2008 Sep 12.

Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk