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Results: 1 to 20 of 123

1.

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.

Kauwe JS, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C, Ainscough BJ, Bales K, Pickering EH, Bertelsen S; Alzheimer's Disease Neuroimaging Initiative, Fagan AM, Holtzman DM, Morris JC, Goate AM.

PLoS Genet. 2014 Oct 23;10(10):e1004758. doi: 10.1371/journal.pgen.1004758. eCollection 2014 Oct.

PMID:
25340798
[PubMed - in process]
Free PMC Article
2.

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.

O'Bryant SE, Gupta V, Henriksen K, Edwards M, Jeromin A, Lista S, Bazenet C, Soares H, Lovestone S, Hampel H, Montine T, Blennow K, Foroud T, Carrillo M, Graff-Radford N, Laske C, Breteler M, Shaw L, Trojanowski JQ, Schupf N, Rissman RA, Fagan AM, Oberoi P, Umek R, Weiner MW, Grammas P, Posner H, Martins R; STAR-B and BBBIG working groups.

Alzheimers Dement. 2014 Sep 27. pii: S1552-5260(14)02765-4. doi: 10.1016/j.jalz.2014.08.099. [Epub ahead of print] Review.

PMID:
25282381
[PubMed - as supplied by publisher]
Free Article
3.

Unrecognized preclinical Alzheimer disease confounds rs-fcMRI studies of normal aging.

Brier MR, Thomas JB, Snyder AZ, Wang L, Fagan AM, Benzinger T, Morris JC, Ances BM.

Neurology. 2014 Oct 28;83(18):1613-9. doi: 10.1212/WNL.0000000000000939. Epub 2014 Sep 26.

PMID:
25261500
[PubMed - in process]
4.

Alzheimer Disease Biomarkers, Attentional Control, and Semantic Memory Retrieval: Synergistic and Mediational Effects of Biomarkers on a Sensitive Cognitive Measure in Non-Demented Older Adults.

Aschenbrenner AJ, Balota DA, Tse CS, Fagan AM, Holtzman DM, Benzinger TL, Morris JC.

Neuropsychology. 2014 Sep 15. [Epub ahead of print]

PMID:
25222200
[PubMed - as supplied by publisher]
5.

Functional connectivity in autosomal dominant and late-onset Alzheimer disease.

Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, Ourselin S, Schofield PR, Masters CL, Martins RN, Weiner MW, Thompson PM, Fox NC, Koeppe RA, Jack CR Jr, Mathis CA, Oliver A, Blazey TM, Moulder K, Buckles V, Hornbeck R, Chhatwal J, Schultz AP, Goate AM, Fagan AM, Cairns NJ, Marcus DS, Morris JC, Ances BM.

JAMA Neurol. 2014 Sep;71(9):1111-22. doi: 10.1001/jamaneurol.2014.1654.

PMID:
25069482
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease.

Blennow K, Dubois B, Fagan AM, Lewczuk P, de Leon MJ, Hampel H.

Alzheimers Dement. 2014 May 2. pii: S1552-5260(14)00066-1. doi: 10.1016/j.jalz.2014.02.004. [Epub ahead of print] Review.

PMID:
24795085
[PubMed - as supplied by publisher]
7.

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease.

Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, Marcus D, Cairns NJ, Buckles VD, Ladenson JH, Morris JC, Holtzman DM; Dominantly Inherited Alzheimer Network.

Sci Transl Med. 2014 Mar 5;6(226):226ra30. doi: 10.1126/scitranslmed.3007901.

PMID:
24598588
[PubMed - indexed for MEDLINE]
8.

Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer's disease in multiplex immunoassay panels of cerebrospinal fluid.

Harari O, Cruchaga C, Kauwe JS, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Goate AM; Alzheimer’s Disease Neuroimaging Initiative.

Biol Psychiatry. 2014 May 1;75(9):723-31. doi: 10.1016/j.biopsych.2013.11.032. Epub 2014 Jan 19.

PMID:
24548642
[PubMed - indexed for MEDLINE]
9.

Missense variant in TREML2 protects against Alzheimer's disease.

Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC; 3C Study Group; EADI consortium; Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Disease Neuroimaging Initiative (ADNI); GERAD Consortium, Williams J, Kauwe JS, Amouyel P, Morgan K, Singleton A, Hardy J, Goate AM, Cruchaga C.

Neurobiol Aging. 2014 Jun;35(6):1510.e19-26. doi: 10.1016/j.neurobiolaging.2013.12.010. Epub 2013 Dec 21.

PMID:
24439484
[PubMed - indexed for MEDLINE]
Free Article
10.

Functional connectivity and graph theory in preclinical Alzheimer's disease.

Brier MR, Thomas JB, Fagan AM, Hassenstab J, Holtzman DM, Benzinger TL, Morris JC, Ances BM.

Neurobiol Aging. 2014 Apr;35(4):757-68. doi: 10.1016/j.neurobiolaging.2013.10.081. Epub 2013 Oct 18.

PMID:
24216223
[PubMed - indexed for MEDLINE]
11.

CSF biomarkers of Alzheimer disease: "noncognitive" outcomes.

Roe CM, Fagan AM, Grant EA, Holtzman DM, Morris JC.

Neurology. 2013 Dec 3;81(23):2028-31. doi: 10.1212/01.wnl.0000436940.78152.05. Epub 2013 Nov 8.

PMID:
24212387
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease.

Benzinger TL, Blazey T, Jack CR Jr, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, Christensen JJ, Ercole L, Hornbeck RC, Farrar AM, Aldea P, Jasielec MS, Owen CJ, Xie X, Mayeux R, Brickman A, McDade E, Klunk W, Mathis CA, Ringman J, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Salloway S, Correia S, Schofield PR, Masters CL, Rowe C, Villemagne VL, Martins R, Ourselin S, Rossor MN, Fox NC, Cash DM, Weiner MW, Holtzman DM, Buckles VD, Moulder K, Morris JC.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4502-9. doi: 10.1073/pnas.1317918110. Epub 2013 Nov 5.

PMID:
24194552
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Relationship between Stroop performance and resting state functional connectivity in cognitively normal older adults.

Duchek JM, Balota DA, Thomas JB, Snyder AZ, Rich P, Benzinger TL, Fagan AM, Holtzman DM, Morris JC, Ances BM.

Neuropsychology. 2013 Sep;27(5):516-28. doi: 10.1037/a0033402.

PMID:
24040929
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Preclinical Alzheimer's disease criteria.

Fagan AM, Vos SJ.

Lancet Neurol. 2013 Dec;12(12):1134. doi: 10.1016/S1474-4422(13)70222-9. Epub 2013 Sep 9. No abstract available.

PMID:
24025450
[PubMed - indexed for MEDLINE]
15.

Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial.

Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, Farlow M, Fox N, Ghetti B, Goate AM, Heinrichs D, Hornbeck R, Jack C, Jucker M, Klunk WE, Marcus DS, Martins RN, Masters CM, Mayeux R, McDade E, Morris JC, Oliver A, Ringman JM, Rossor MN, Salloway S, Schofield PR, Snider J, Snyder P, Sperling RA, Stewart C, Thomas RG, Xiong C, Bateman RJ.

Rev Neurol (Paris). 2013 Oct;169(10):737-43. doi: 10.1016/j.neurol.2013.07.017. Epub 2013 Sep 6. Review.

PMID:
24016464
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study.

Vos SJ, Xiong C, Visser PJ, Jasielec MS, Hassenstab J, Grant EA, Cairns NJ, Morris JC, Holtzman DM, Fagan AM.

Lancet Neurol. 2013 Oct;12(10):957-65. doi: 10.1016/S1474-4422(13)70194-7. Epub 2013 Sep 4.

PMID:
24012374
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Progress update: fluid and imaging biomarkers in Alzheimer's disease.

Sutphen CL, Fagan AM, Holtzman DM.

Biol Psychiatry. 2014 Apr 1;75(7):520-6. doi: 10.1016/j.biopsych.2013.07.031. Epub 2013 Sep 5. Review.

PMID:
24012326
[PubMed - indexed for MEDLINE]
18.

The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.

Benitez BA, Karch CM, Cai Y, Jin SC, Cooper B, Carrell D, Bertelsen S, Chibnik L, Schneider JA, Bennett DA; Alzheimer's Disease Neuroimaging Initiative; Genetic and Environmental Risk for Alzheimer's Disease Consortium GERAD, Fagan AM, Holtzman D, Morris JC, Goate AM, Cruchaga C.

PLoS Genet. 2013;9(8):e1003685. doi: 10.1371/journal.pgen.1003685. Epub 2013 Aug 22.

PMID:
23990795
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cerebrospinal fluid Aβ42, phosphorylated Tau181, and resting-state functional connectivity.

Wang L, Brier MR, Snyder AZ, Thomas JB, Fagan AM, Xiong C, Benzinger TL, Holtzman DM, Morris JC, Ances BM.

JAMA Neurol. 2013 Oct;70(10):1242-8.

PMID:
23959173
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Impaired default network functional connectivity in autosomal dominant Alzheimer disease.

Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C Jr, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, Rowe CC, Fox NC, Brickman AM, Mayeux R, McDade E, Bateman R, Fagan AM, Goate AM, Xiong C, Buckles VD, Morris JC, Sperling RA.

Neurology. 2013 Aug 20;81(8):736-44. doi: 10.1212/WNL.0b013e3182a1aafe. Epub 2013 Jul 24.

PMID:
23884042
[PubMed - indexed for MEDLINE]
Free PMC Article

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