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Results: 1 to 20 of 153

1.

Youth advocacy as a tool for environmental and policy changes that support physical activity and nutrition: an evaluation study in San Diego County.

Linton LS, Edwards CC, Woodruff SI, Millstein RA, Moder C.

Prev Chronic Dis. 2014 Mar 27;11:E46. doi: 10.5888/pcd11.130321.

PMID:
24674636
[PubMed - in process]
Free PMC Article
2.

Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").

Hatfield MJ, Tsurkan LG, Hyatt JL, Edwards CC, Lemoff A, Jeffries C, Yan B, Potter PM.

J Nat Prod. 2013 Jan 25;76(1):36-44. doi: 10.1021/np300628a. Epub 2013 Jan 3.

PMID:
23286284
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors.

Tsurkan LG, Hatfield MJ, Edwards CC, Hyatt JL, Potter PM.

Chem Biol Interact. 2013 Mar 25;203(1):226-30. doi: 10.1016/j.cbi.2012.10.018. Epub 2012 Nov 2.

PMID:
23123248
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones.

Parkinson EI, Jason Hatfield M, Tsurkan L, Hyatt JL, Edwards CC, Hicks LD, Yan B, Potter PM.

Bioorg Med Chem. 2011 Aug 1;19(15):4635-43. doi: 10.1016/j.bmc.2011.06.012. Epub 2011 Jul 4.

PMID:
21733699
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles.

Edwards JS, Kumbhar A, Roberts A, Hemmert AC, Edwards CC, Potter PM, Redinbo MR.

Biotechnol Prog. 2011 May-Jun;27(3):863-9. doi: 10.1002/btpr.604. Epub 2011 Apr 20.

PMID:
21509954
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Nerve agent hydrolysis activity designed into a human drug metabolism enzyme.

Hemmert AC, Otto TC, Chica RA, Wierdl M, Edwards JS, Lewis SM, Edwards CC, Tsurkan L, Cadieux CL, Kasten SA, Cashman JR, Mayo SL, Potter PM, Cerasoli DM, Redinbo MR.

PLoS One. 2011 Mar 18;6(3):e17441. doi: 10.1371/journal.pone.0017441. Erratum in: PLoS One. 2012;7(1). doi:10.1371/annotation/c5953f27-95f8-4a1b-a46c-639d90e182ac. Lewis, Steven L [corrected to Lewis, Steven M].

PMID:
21445272
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing.

Fan L, Lagisetti C, Edwards CC, Webb TR, Potter PM.

ACS Chem Biol. 2011 Jun 17;6(6):582-9. doi: 10.1021/cb100356k. Epub 2011 Mar 7.

PMID:
21344922
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2.

Xie S, Borazjani A, Hatfield MJ, Edwards CC, Potter PM, Ross MK.

Chem Res Toxicol. 2010 Dec 20;23(12):1890-904. doi: 10.1021/tx1002194.

PMID:
21049984
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11.

Hatfield MJ, Tsurkan L, Garrett M, Shaver TM, Hyatt JL, Edwards CC, Hicks LD, Potter PM.

Biochem Pharmacol. 2011 Jan 1;81(1):24-31. doi: 10.1016/j.bcp.2010.09.001. Epub 2010 Sep 15.

PMID:
20833148
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.

Hatfield MJ, Tsurkan L, Hyatt JL, Yu X, Edwards CC, Hicks LD, Wadkins RM, Potter PM.

Br J Pharmacol. 2010 Aug;160(8):1916-28. doi: 10.1111/j.1476-5381.2010.00700.x.

PMID:
20649590
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin.

Hemmert AC, Otto TC, Wierdl M, Edwards CC, Fleming CD, MacDonald M, Cashman JR, Potter PM, Cerasoli DM, Redinbo MR.

Mol Pharmacol. 2010 Apr;77(4):508-16. doi: 10.1124/mol.109.062356. Epub 2010 Jan 5.

PMID:
20051531
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity.

Hicks LD, Hyatt JL, Stoddard S, Tsurkan L, Edwards CC, Wadkins RM, Potter PM.

J Med Chem. 2009 Jun 25;52(12):3742-52. doi: 10.1021/jm9001296.

PMID:
19534556
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Reliability analysis for manual radiographic measures of rotatory subluxation or lateral listhesis in adult scoliosis.

Freedman BA, Horton WC, Rhee JM, Edwards CC 2nd, Kuklo TR.

Spine (Phila Pa 1976). 2009 Mar 15;34(6):603-8. doi: 10.1097/BRS.0b013e31819a841e.

PMID:
19282739
[PubMed - indexed for MEDLINE]
14.

An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11.

Wierdl M, Tsurkan L, Hyatt JL, Edwards CC, Hatfield MJ, Morton CL, Houghton PJ, Danks MK, Redinbo MR, Potter PM.

Cancer Gene Ther. 2008 Mar;15(3):183-92. doi: 10.1038/sj.cgt.7701112. Epub 2008 Jan 11.

PMID:
18188187
[PubMed - indexed for MEDLINE]
15.

Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug.

Barthel BL, Torres RC, Hyatt JL, Edwards CC, Hatfield MJ, Potter PM, Koch TH.

J Med Chem. 2008 Jan 24;51(2):298-304. doi: 10.1021/jm7011479. Epub 2008 Jan 4.

PMID:
18173233
[PubMed - indexed for MEDLINE]
16.

Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1.

Hyatt JL, Wadkins RM, Tsurkan L, Hicks LD, Hatfield MJ, Edwards CC, Ross CR 2nd, Cantalupo SA, Crundwell G, Danks MK, Guy RK, Potter PM.

J Med Chem. 2007 Nov 15;50(23):5727-34. Epub 2007 Oct 17.

PMID:
17941623
[PubMed - indexed for MEDLINE]
17.

Sociodemographic and smoking-related psychosocial predictors of smoking behavior change among high school smokers.

Woodruff SI, Conway TL, Edwards CC.

Addict Behav. 2008 Feb;33(2):354-8. Epub 2007 Sep 8.

PMID:
17900818
[PubMed - indexed for MEDLINE]
18.

Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun.

Fleming CD, Edwards CC, Kirby SD, Maxwell DM, Potter PM, Cerasoli DM, Redinbo MR.

Biochemistry. 2007 May 1;46(17):5063-71. Epub 2007 Apr 4.

PMID:
17407327
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils.

Hicks LD, Hyatt JL, Moak T, Edwards CC, Tsurkan L, Wierdl M, Ferreira AM, Wadkins RM, Potter PM.

Bioorg Med Chem. 2007 Jun 1;15(11):3801-17. Epub 2007 Mar 12.

PMID:
17399985
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Selective inhibition of carboxylesterases by isatins, indole-2,3-diones.

Hyatt JL, Moak T, Hatfield MJ, Tsurkan L, Edwards CC, Wierdl M, Danks MK, Wadkins RM, Potter PM.

J Med Chem. 2007 Apr 19;50(8):1876-85. Epub 2007 Mar 23.

PMID:
17378546
[PubMed - indexed for MEDLINE]

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