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Results: 1 to 20 of 76

1.

Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells.

Fenwick PS, Macedo P, Kilty IC, Barnes PJ, Donnelly LE.

PLoS One. 2015 Jun 19;10(6):e0128757. doi: 10.1371/journal.pone.0128757. eCollection 2015.

2.

Corrigendum: Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes.

Ilott NE, Heward JA, Roux B, Tsitsiou E, Fenwick PS, Lenzi L, Goodhead I, Hertz-Fowler C, Heger A, Hall N, Donnelly LE, Sims D, Lindsay MA.

Nat Commun. 2015 Apr 9;6:6814. doi: 10.1038/ncomms7814. No abstract available.

PMID:
25855049
3.

Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease.

Singh R, Mackay AJ, Patel AR, Garcha DS, Kowlessar BS, Brill SE, Donnelly LE, Barnes PJ, Donaldson GC, Wedzicha JA.

Respir Res. 2014 Sep 14;15:114. doi: 10.1186/s12931-014-0114-1.

4.

The lipidome: a new player in chronic obstructive pulmonary disease pathophysiology?

Donnelly LE.

Am J Respir Crit Care Med. 2014 Jul 15;190(2):124-5. doi: 10.1164/rccm.201406-1061ED. No abstract available.

PMID:
25025348
5.

Impaired macrophage phagocytosis of bacteria in severe asthma.

Liang Z, Zhang Q, Thomas CM, Chana KK, Gibeon D, Barnes PJ, Chung KF, Bhavsar PK, Donnelly LE.

Respir Res. 2014 Jun 27;15:72. doi: 10.1186/1465-9921-15-72.

6.

Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes.

IIott NE, Heward JA, Roux B, Tsitsiou E, Fenwick PS, Lenzi L, Goodhead I, Hertz-Fowler C, Heger A, Hall N, Donnelly LE, Sims D, Lindsay MA.

Nat Commun. 2014 Jun 9;5:3979. doi: 10.1038/ncomms4979.

7.

Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses.

Forbes B, O'Lone R, Allen PP, Cahn A, Clarke C, Collinge M, Dailey LA, Donnelly LE, Dybowski J, Hassall D, Hildebrand D, Jones R, Kilgour J, Klapwijk J, Maier CC, McGovern T, Nikula K, Parry JD, Reed MD, Robinson I, Tomlinson L, Wolfreys A.

Adv Drug Deliv Rev. 2014 May;71:15-33. doi: 10.1016/j.addr.2014.02.001. Epub 2014 Feb 13.

8.

Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease.

Chana KK, Fenwick PS, Nicholson AG, Barnes PJ, Donnelly LE.

J Allergy Clin Immunol. 2014 Jan;133(1):207-16.e1-11. doi: 10.1016/j.jaci.2013.08.044. Epub 2013 Oct 28.

PMID:
24176116
9.

A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.

Brown SM, Koarai A, Sturton RG, Nicholson AG, Barnes PJ, Donnelly LE.

Eur J Pharmacol. 2013 Feb 28;702(1-3):109-15. doi: 10.1016/j.ejphar.2013.01.054. Epub 2013 Feb 8.

PMID:
23396230
10.

Immunopathogenesis of chronic obstructive pulmonary disease.

Holloway RA, Donnelly LE.

Curr Opin Pulm Med. 2013 Mar;19(2):95-102. doi: 10.1097/MCP.0b013e32835cfff5. Review.

PMID:
23325031
11.

Defective phagocytosis in airways disease.

Donnelly LE, Barnes PJ.

Chest. 2012 Apr;141(4):1055-62. doi: 10.1378/chest.11-2348. Review.

PMID:
22474147
12.

Expression of muscarinic receptors by human macrophages.

Koarai A, Traves SL, Fenwick PS, Brown SM, Chana KK, Russell RE, Nicholson AG, Barnes PJ, Donnelly LE.

Eur Respir J. 2012 Mar;39(3):698-704. doi: 10.1183/09031936.00136710. Epub 2011 Sep 1.

13.

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress.

Mercado N, Thimmulappa R, Thomas CM, Fenwick PS, Chana KK, Donnelly LE, Biswal S, Ito K, Barnes PJ.

Biochem Biophys Res Commun. 2011 Mar 11;406(2):292-8. doi: 10.1016/j.bbrc.2011.02.035. Epub 2011 Feb 12.

14.

Effects of formoterol and salmeterol on cytokine release from monocyte-derived macrophages.

Donnelly LE, Tudhope SJ, Fenwick PS, Barnes PJ.

Eur Respir J. 2010 Jul;36(1):178-86. doi: 10.1183/09031936.00158008. Epub 2009 Nov 19.

15.

Defective macrophage phagocytosis of bacteria in COPD.

Taylor AE, Finney-Hayward TK, Quint JK, Thomas CM, Tudhope SJ, Wedzicha JA, Barnes PJ, Donnelly LE.

Eur Respir J. 2010 May;35(5):1039-47. doi: 10.1183/09031936.00036709. Epub 2009 Nov 6.

16.

Expression of transient receptor potential C6 channels in human lung macrophages.

Finney-Hayward TK, Popa MO, Bahra P, Li S, Poll CT, Gosling M, Nicholson AG, Russell RE, Kon OM, Jarai G, Westwick J, Barnes PJ, Donnelly LE.

Am J Respir Cell Mol Biol. 2010 Sep;43(3):296-304. doi: 10.1165/rcmb.2008-0373OC. Epub 2009 Oct 20.

PMID:
19843708
17.

Leukotriene B4 release by human lung macrophages via receptor- not voltage-operated Ca2+ channels.

Finney-Hayward TK, Bahra P, Li S, Poll CT, Nicholson AG, Russell RE, Ford PA, Westwick J, Fenwick PS, Barnes PJ, Donnelly LE.

Eur Respir J. 2009 May;33(5):1105-12. doi: 10.1183/09031936.00062708. Epub 2009 Jan 22.

18.

Th17 cells in airway diseases.

Traves SL, Donnelly LE.

Curr Mol Med. 2008 Aug;8(5):416-26. Review.

PMID:
18691069
19.

Novel targets and drugs in inflammatory lung disease.

Donnelly LE, Rogers DF.

Curr Opin Pharmacol. 2008 Jun;8(3):219-21. doi: 10.1016/j.coph.2008.04.007. Epub 2008 May 22. No abstract available.

PMID:
18502177
20.

The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells.

Tudhope SJ, Catley MC, Fenwick PS, Russell RE, Rumsey WL, Newton R, Barnes PJ, Donnelly LE.

J Immunol. 2007 Nov 1;179(9):6237-45.

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