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    Results: 1 to 20 of 68

    1.

    A role for M2 and M3 muscarinic receptors in the contraction of rat and human small airways.

    Brown SM, Koarai A, Sturton RG, Nicholson AG, Barnes PJ, Donnelly LE.

    Eur J Pharmacol. 2013 Feb 28;702(1-3):109-15. doi: 10.1016/j.ejphar.2013.01.054. Epub 2013 Feb 8.

    PMID:
    23396230
    [PubMed - in process]
    2.

    Immunopathogenesis of chronic obstructive pulmonary disease.

    Holloway RA, Donnelly LE.

    Curr Opin Pulm Med. 2013 Mar;19(2):95-102. doi: 10.1097/MCP.0b013e32835cfff5.

    PMID:
    23325031
    [PubMed - in process]
    3.

    Defective phagocytosis in airways disease.

    Donnelly LE, Barnes PJ.

    Chest. 2012 Apr;141(4):1055-62. doi: 10.1378/chest.11-2348. Review.

    PMID:
    22474147
    [PubMed - indexed for MEDLINE]
    4.

    Expression of muscarinic receptors by human macrophages.

    Koarai A, Traves SL, Fenwick PS, Brown SM, Chana KK, Russell RE, Nicholson AG, Barnes PJ, Donnelly LE.

    Eur Respir J. 2012 Mar;39(3):698-704. doi: 10.1183/09031936.00136710. Epub 2011 Sep 1.

    PMID:
    21885397
    [PubMed - indexed for MEDLINE]
    5.

    Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress.

    Mercado N, Thimmulappa R, Thomas CM, Fenwick PS, Chana KK, Donnelly LE, Biswal S, Ito K, Barnes PJ.

    Biochem Biophys Res Commun. 2011 Mar 11;406(2):292-8. doi: 10.1016/j.bbrc.2011.02.035. Epub 2011 Feb 12.

    PMID:
    21320471
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Effects of formoterol and salmeterol on cytokine release from monocyte-derived macrophages.

    Donnelly LE, Tudhope SJ, Fenwick PS, Barnes PJ.

    Eur Respir J. 2010 Jul;36(1):178-86. doi: 10.1183/09031936.00158008. Epub 2009 Nov 19.

    PMID:
    19926732
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Defective macrophage phagocytosis of bacteria in COPD.

    Taylor AE, Finney-Hayward TK, Quint JK, Thomas CM, Tudhope SJ, Wedzicha JA, Barnes PJ, Donnelly LE.

    Eur Respir J. 2010 May;35(5):1039-47. doi: 10.1183/09031936.00036709. Epub 2009 Nov 6.

    PMID:
    19897561
    [PubMed - indexed for MEDLINE]
    Free Article
    8.

    Expression of transient receptor potential C6 channels in human lung macrophages.

    Finney-Hayward TK, Popa MO, Bahra P, Li S, Poll CT, Gosling M, Nicholson AG, Russell RE, Kon OM, Jarai G, Westwick J, Barnes PJ, Donnelly LE.

    Am J Respir Cell Mol Biol. 2010 Sep;43(3):296-304. doi: 10.1165/rcmb.2008-0373OC. Epub 2009 Oct 20.

    PMID:
    19843708
    [PubMed - indexed for MEDLINE]
    9.

    Leukotriene B4 release by human lung macrophages via receptor- not voltage-operated Ca2+ channels.

    Finney-Hayward TK, Bahra P, Li S, Poll CT, Nicholson AG, Russell RE, Ford PA, Westwick J, Fenwick PS, Barnes PJ, Donnelly LE.

    Eur Respir J. 2009 May;33(5):1105-12. doi: 10.1183/09031936.00062708. Epub 2009 Jan 22.

    PMID:
    19164358
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Th17 cells in airway diseases.

    Traves SL, Donnelly LE.

    Curr Mol Med. 2008 Aug;8(5):416-26. Review.

    PMID:
    18691069
    [PubMed - indexed for MEDLINE]
    11.

    Novel targets and drugs in inflammatory lung disease.

    Donnelly LE, Rogers DF.

    Curr Opin Pharmacol. 2008 Jun;8(3):219-21. doi: 10.1016/j.coph.2008.04.007. Epub 2008 May 22. No abstract available.

    PMID:
    18502177
    [PubMed - indexed for MEDLINE]
    12.

    The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells.

    Tudhope SJ, Catley MC, Fenwick PS, Russell RE, Rumsey WL, Newton R, Barnes PJ, Donnelly LE.

    J Immunol. 2007 Nov 1;179(9):6237-45.

    PMID:
    17947699
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    CXCR3 and CCR5 chemokines in induced sputum from patients with COPD.

    Costa C, Rufino R, Traves SL, Lapa E Silva JR, Barnes PJ, Donnelly LE.

    Chest. 2008 Jan;133(1):26-33. Epub 2007 Oct 9.

    PMID:
    17925429
    [PubMed - indexed for MEDLINE]
    14.

    Different mitogen-activated protein kinase-dependent cytokine responses in cells of the monocyte lineage.

    Tudhope SJ, Finney-Hayward TK, Nicholson AG, Mayer RJ, Barnette MS, Barnes PJ, Donnelly LE.

    J Pharmacol Exp Ther. 2008 Jan;324(1):306-12. Epub 2007 Oct 5.

    PMID:
    17921189
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease.

    Grandhi S, Donnelly LE, Rogers DF.

    Expert Rev Respir Med. 2007 Oct;1(2):227-46. doi: 10.1586/17476348.1.2.227.

    PMID:
    20477187
    [PubMed]
    16.

    The non-neuronal cholinergic system in the airways: an unappreciated regulatory role in pulmonary inflammation?

    Gwilt CR, Donnelly LE, Rogers DF.

    Pharmacol Ther. 2007 Aug;115(2):208-22. Epub 2007 May 25. Review.

    PMID:
    17597218
    [PubMed - indexed for MEDLINE]
    17.

    Analysis of the dissociated steroid RU24858 does not exclude a role for inducible genes in the anti-inflammatory actions of glucocorticoids.

    Chivers JE, Gong W, King EM, Seybold J, Mak JC, Donnelly LE, Holden NS, Newton R.

    Mol Pharmacol. 2006 Dec;70(6):2084-95. Epub 2006 Sep 20.

    PMID:
    16988013
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages.

    Smith SJ, Fenwick PS, Nicholson AG, Kirschenbaum F, Finney-Hayward TK, Higgins LS, Giembycz MA, Barnes PJ, Donnelly LE.

    Br J Pharmacol. 2006 Oct;149(4):393-404. Epub 2006 Sep 4.

    PMID:
    16953188
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease.

    Donnelly LE, Barnes PJ.

    Trends Pharmacol Sci. 2006 Oct;27(10):546-53. Epub 2006 Aug 30. Review.

    PMID:
    16911834
    [PubMed - indexed for MEDLINE]
    20.

    Sputum matrix metalloproteases: comparison between chronic obstructive pulmonary disease and asthma.

    Culpitt SV, Rogers DF, Traves SL, Barnes PJ, Donnelly LE.

    Respir Med. 2005 Jun;99(6):703-10. Epub 2004 Dec 13.

    PMID:
    15878486
    [PubMed - indexed for MEDLINE]

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