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Results: 1 to 20 of 326

1.

Effect of reducing the paediatric stavudine dose by half: A physiologically-based pharmacokinetic model.

Sy SK, Malmberg R, Matsushima A, Asin-Prieto E, Rosenkranz B, Cotton MF, Derendorf H, Innes S.

Int J Antimicrob Agents. 2015 Jan 19. pii: S0924-8579(15)00010-2. doi: 10.1016/j.ijantimicag.2014.12.016. [Epub ahead of print]

PMID:
25697412
[PubMed - as supplied by publisher]
2.

Development and validation of a HPLC-MS/MS method for the determination of phytolaccagenin in rat plasma and application to a pharmacokinetic study.

Wei F, Singh RS, Fueth M, Swarts S, Okunieff P, Derendorf H.

J Pharm Biomed Anal. 2014 Dec 22;107C:82-88. doi: 10.1016/j.jpba.2014.12.025. [Epub ahead of print]

PMID:
25575173
[PubMed - as supplied by publisher]
3.

Evaluation of in vitro synergy between vertilmicin and ceftazidime against Pseudomonas aeruginosa using a semi-mechanistic pharmacokinetic/pharmacodynamic model.

Zhuang L, Sy SK, Xia H, Singh RP, Mulder MB, Liu C, Derendorf H.

Int J Antimicrob Agents. 2015 Feb;45(2):151-60. doi: 10.1016/j.ijantimicag.2014.09.017. Epub 2014 Nov 1.

PMID:
25465523
[PubMed - in process]
4.

Concentration-response studies and modelling of the pharmacodynamics of linezolid: Staphylococcus aureus versus Enterococcus faecium.

Scheerans C, Wicha SG, Michael J, Derendorf H, Kloft C.

Int J Antimicrob Agents. 2015 Jan;45(1):54-60. doi: 10.1016/j.ijantimicag.2014.07.028. Epub 2014 Oct 22.

PMID:
25455852
[PubMed - in process]
5.

Enhanced penetration of moxifloxacin into rat prostate tissue evidenced by microdialysis.

K Hurtado F, Laureano JV, de A Lock G, Derendorf H, Dalla Costa T.

Int J Antimicrob Agents. 2014 Oct;44(4):327-33. doi: 10.1016/j.ijantimicag.2014.06.011. Epub 2014 Jul 29.

PMID:
25218157
[PubMed - in process]
6.

Measuring drug distribution in the critically ill patient.

Deitchman AN, Derendorf H.

Adv Drug Deliv Rev. 2014 Nov 20;77:22-6. doi: 10.1016/j.addr.2014.08.014. Epub 2014 Sep 3. Review.

PMID:
25194997
[PubMed - in process]
7.

Predicting pediatric age-matched weight and body mass index.

Sy SK, Asin-Prieto E, Derendorf H, Samara E.

AAPS J. 2014 Nov;16(6):1372-9. doi: 10.1208/s12248-014-9657-9. Epub 2014 Aug 26.

PMID:
25155824
[PubMed - in process]
8.

Pharmacokinetics of para-aminosalicylic acid in HIV-uninfected and HIV-coinfected tuberculosis patients receiving antiretroviral therapy, managed for multidrug-resistant and extensively drug-resistant tuberculosis.

de Kock L, Sy SK, Rosenkranz B, Diacon AH, Prescott K, Hernandez KR, Yu M, Derendorf H, Donald PR.

Antimicrob Agents Chemother. 2014 Oct;58(10):6242-50. doi: 10.1128/AAC.03073-14. Epub 2014 Aug 11.

PMID:
25114132
[PubMed - in process]
9.

Relevance of Liver Failure for Anti-Infective Agents: From Pharmacokinetic Alterations to Dosage Adjustments.

Bϋdingen FV, Gonzalez D, Tucker AN, Derendorf H.

Ther Adv Infect Dis. 2014 Feb 1;2(1):17-42.

PMID:
24949199
[PubMed]
Free PMC Article
10.

Population pharmacokinetics of cilengitide in adult and pediatric cancer patients from a nonlinear mixed-effects analysis.

Zühlsdorf M, Bhattaram VA, Campioni M, Krösser S, Derendorf H, Kovar A.

J Clin Pharmacol. 2014 Dec;54(12):1391-9. doi: 10.1002/jcph.343. Epub 2014 Jun 26.

PMID:
24911832
[PubMed - in process]
11.

Protein binding of rifapentine and its 25-desacetyl metabolite in patients with pulmonary tuberculosis.

Egelund EF, Weiner M, Singh RP, Prihoda TJ, Gelfond JA, Derendorf H, Mac Kenzie WR, Peloquin CA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4904-10. doi: 10.1128/AAC.01730-13. Epub 2014 May 19.

PMID:
24841270
[PubMed - in process]
Free PMC Article
12.

Pharmacokinetic modelling of serum and bronchial concentrations for clarithromycin and telithromycin, and site-specific pharmacodynamic simulation for their dosages.

Ikawa K, Kikuchi E, Kikuchi J, Nishimura M, Derendorf H, Morikawa N.

J Clin Pharm Ther. 2014 Aug;39(4):411-7. doi: 10.1111/jcpt.12157. Epub 2014 Mar 24.

PMID:
24661290
[PubMed - in process]
13.

Largazole pharmacokinetics in rats by LC-MS/MS.

Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H.

Mar Drugs. 2014 Mar 20;12(3):1623-40. doi: 10.3390/md12031623.

PMID:
24658499
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Comparison of skin permeability for three diclofenac topical formulations: an in vitro study.

Folzer E, Gonzalez D, Singh R, Derendorf H.

Pharmazie. 2014 Jan;69(1):27-31.

PMID:
24601219
[PubMed - indexed for MEDLINE]
15.

Determination of atypical nonlinear plasma−protein-binding behavior of tigecycline using an in vitro microdialysis technique.

Mukker JK, Singh RP, Derendorf H.

J Pharm Sci. 2014 Mar;103(3):1013-9. doi: 10.1002/jps.23872. Epub 2014 Jan 24.

PMID:
24549736
[PubMed - indexed for MEDLINE]
16.

Clinical development of an advanced intranasal delivery system of azelastine hydrochloride and fluticasone propionate.

Derendorf H, Meltzer EO, Hermann R, Canonica GW.

Drugs Today (Barc). 2014 Jan;50(1):15-31. doi: 10.1358/dot.2014.50.1.2094806.

PMID:
24524103
[PubMed - in process]
17.

Role of microdialysis in pharmacokinetics and pharmacodynamics: current status and future directions.

Azeredo FJ, Dalla Costa T, Derendorf H.

Clin Pharmacokinet. 2014 Mar;53(3):205-12. doi: 10.1007/s40262-014-0131-8. Review.

PMID:
24452811
[PubMed - indexed for MEDLINE]
18.

Estimation of intracellular concentration of stavudine triphosphate in HIV-infected children given a reduced dose of 0.5 milligrams per kilogram twice daily.

Sy SK, Innes S, Derendorf H, Cotton MF, Rosenkranz B.

Antimicrob Agents Chemother. 2014;58(2):1084-91. doi: 10.1128/AAC.01717-13. Epub 2013 Dec 2.

PMID:
24295968
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis.

Hurtado FK, Weber B, Derendorf H, Hochhaus G, Dalla Costa T.

Antimicrob Agents Chemother. 2014;58(2):678-86. doi: 10.1128/AAC.01884-13. Epub 2013 Nov 11.

PMID:
24217697
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Application of pharmacokinetic/pharmacodynamic modelling and simulation for the prediction of target attainment of ceftobiprole against meticillin-resistant Staphylococcus aureus using minimum inhibitory concentration and time-kill curve based approaches.

Barbour AM, Schmidt S, Zhuang L, Rand K, Derendorf H.

Int J Antimicrob Agents. 2014 Jan;43(1):60-7. doi: 10.1016/j.ijantimicag.2013.08.016. Epub 2013 Oct 1.

PMID:
24183800
[PubMed - indexed for MEDLINE]
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