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Results: 1 to 20 of 318

1.

Relevance of Liver Failure for Anti-Infective Agents: From Pharmacokinetic Alterations to Dosage Adjustments.

Bϋdingen FV, Gonzalez D, Tucker AN, Derendorf H.

Ther Adv Infect Dis. 2014 Feb 1;2(1):17-42.

PMID:
24949199
[PubMed]
2.

Population pharmacokinetics of cilengitide in adult and pediatric cancer patients from a nonlinear mixed-effects analysis.

Zühlsdorf M, Bhattaram VA, Campioni M, Krösser S, Derendorf H, Kovar A.

J Clin Pharmacol. 2014 Jun 9. doi: 10.1002/jcph.343. [Epub ahead of print]

PMID:
24911832
[PubMed - as supplied by publisher]
3.

Protein binding of rifapentine and its 25-desacetyl metabolite in patients with pulmonary tuberculosis.

Egelund EF, Weiner M, Singh RP, Prihoda TJ, Gelfond JA, Derendorf H, Mac Kenzie WR, Peloquin CA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4904-10. doi: 10.1128/AAC.01730-13. Epub 2014 May 19.

PMID:
24841270
[PubMed - in process]
4.

Pharmacokinetic modelling of serum and bronchial concentrations for clarithromycin and telithromycin, and site-specific pharmacodynamic simulation for their dosages.

Ikawa K, Kikuchi E, Kikuchi J, Nishimura M, Derendorf H, Morikawa N.

J Clin Pharm Ther. 2014 Aug;39(4):411-7. doi: 10.1111/jcpt.12157. Epub 2014 Mar 24.

PMID:
24661290
[PubMed - in process]
5.

Largazole pharmacokinetics in rats by LC-MS/MS.

Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H.

Mar Drugs. 2014 Mar 20;12(3):1623-40. doi: 10.3390/md12031623.

PMID:
24658499
[PubMed - in process]
Free PMC Article
6.

Comparison of skin permeability for three diclofenac topical formulations: an in vitro study.

Folzer E, Gonzalez D, Singh R, Derendorf H.

Pharmazie. 2014 Jan;69(1):27-31.

PMID:
24601219
[PubMed - indexed for MEDLINE]
7.

Determination of atypical nonlinear plasma-protein-binding behavior of tigecycline using an in vitro microdialysis technique.

Mukker JK, Singh RP, Derendorf H.

J Pharm Sci. 2014 Mar;103(3):1013-9. doi: 10.1002/jps.23872. Epub 2014 Jan 24.

PMID:
24549736
[PubMed - in process]
8.

Clinical development of an advanced intranasal delivery system of azelastine hydrochloride and fluticasone propionate.

Derendorf H, Meltzer EO, Hermann R, Canonica GW.

Drugs Today (Barc). 2014 Jan;50(1):15-31. doi: 10.1358/dot.2014.50.1.2094806.

PMID:
24524103
[PubMed - in process]
9.

Role of microdialysis in pharmacokinetics and pharmacodynamics: current status and future directions.

Azeredo FJ, Dalla Costa T, Derendorf H.

Clin Pharmacokinet. 2014 Mar;53(3):205-12. doi: 10.1007/s40262-014-0131-8.

PMID:
24452811
[PubMed - in process]
10.

Estimation of intracellular concentration of stavudine triphosphate in HIV-infected children given a reduced dose of 0.5 milligrams per kilogram twice daily.

Sy SK, Innes S, Derendorf H, Cotton MF, Rosenkranz B.

Antimicrob Agents Chemother. 2014 Feb;58(2):1084-91. doi: 10.1128/AAC.01717-13. Epub 2013 Dec 2.

PMID:
24295968
[PubMed - in process]
11.

Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis.

Hurtado FK, Weber B, Derendorf H, Hochhaus G, Dalla Costa T.

Antimicrob Agents Chemother. 2014 Feb;58(2):678-86. doi: 10.1128/AAC.01884-13. Epub 2013 Nov 11.

PMID:
24217697
[PubMed - in process]
12.

Application of pharmacokinetic/pharmacodynamic modelling and simulation for the prediction of target attainment of ceftobiprole against meticillin-resistant Staphylococcus aureus using minimum inhibitory concentration and time-kill curve based approaches.

Barbour AM, Schmidt S, Zhuang L, Rand K, Derendorf H.

Int J Antimicrob Agents. 2014 Jan;43(1):60-7. doi: 10.1016/j.ijantimicag.2013.08.016. Epub 2013 Oct 1.

PMID:
24183800
[PubMed - indexed for MEDLINE]
13.

A Markov chain model to evaluate the effect of CYP3A5 and ABCB1 polymorphisms on adverse events associated with tacrolimus in pediatric renal transplantation.

Sy SK, Heuberger J, Shilbayeh S, Conrado DJ, Derendorf H.

AAPS J. 2013 Oct;15(4):1189-99. doi: 10.1208/s12248-013-9528-9. Epub 2013 Aug 30.

PMID:
23990505
[PubMed - indexed for MEDLINE]
14.

Electroencephalogram effects of armodafinil: comparison with behavioral alertness.

Conrado DJ, Bewernitz M, Ding M, Cibula J, Seubert C, Sy SK, Eisenschenk S, Derendorf H.

J Clin Pharmacol. 2013 Oct;53(10):1058-71. doi: 10.1002/jcph.143. Epub 2013 Aug 1.

PMID:
23913585
[PubMed - indexed for MEDLINE]
15.

Sex related differences on valproic acid pharmacokinetics after oral single dose.

Ibarra M, Vázquez M, Fagiolino P, Derendorf H.

J Pharmacokinet Pharmacodyn. 2013 Aug;40(4):479-86. doi: 10.1007/s10928-013-9323-3. Epub 2013 Jun 20.

PMID:
23784346
[PubMed - indexed for MEDLINE]
16.

Pharmacokinetic properties of pure xanthones in comparison to a mangosteen fruit extract in rats.

Li L, Han AR, Kinghorn AD, Frye RF, Derendorf H, Butterweck V.

Planta Med. 2013 May;79(8):646-53. doi: 10.1055/s-0032-1328543. Epub 2013 May 14.

PMID:
23673465
[PubMed - indexed for MEDLINE]
17.

When is protein binding important?

Heuberger J, Schmidt S, Derendorf H.

J Pharm Sci. 2013 Sep;102(9):3458-67. doi: 10.1002/jps.23559. Epub 2013 May 6.

PMID:
23650013
[PubMed - indexed for MEDLINE]
18.

Pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator, in the first-in-human study.

Brossard P, Derendorf H, Xu J, Maatouk H, Halabi A, Dingemanse J.

Br J Clin Pharmacol. 2013 Dec;76(6):888-96. doi: 10.1111/bcp.12129.

PMID:
23594176
[PubMed - indexed for MEDLINE]
19.

Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents.

Gonzalez D, Schmidt S, Derendorf H.

Clin Microbiol Rev. 2013 Apr;26(2):274-88. doi: 10.1128/CMR.00092-12. Review.

PMID:
23554417
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Grapefruit-medication interactions.

Greenblatt DJ, Derendorf H.

CMAJ. 2013 Apr 2;185(6):507. doi: 10.1503/cmaj.113-2109. No abstract available.

PMID:
23550054
[PubMed - indexed for MEDLINE]
Free PMC Article

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