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Year Number of Results
1976 1
1983 1
1990 1
1994 1
1995 1
2000 1
2002 1
2008 1
2012 2
2013 3
2014 4
2016 1
2017 1
2018 1
2019 3
2020 3
2021 6
2022 5
2023 6
2024 5

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Page 1
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
Kotsiliti E, Leone V, Schuehle S, Govaere O, Li H, Wolf MJ, Horvatic H, Bierwirth S, Hundertmark J, Inverso D, Zizmare L, Sarusi-Portuguez A, Gupta R, O'Connor T, Giannou AD, Shiri AM, Schlesinger Y, Beccaria MG, Rennert C, Pfister D, Öllinger R, Gadjalova I, Ramadori P, Rahbari M, Rahbari N, Healy ME, Fernández-Vaquero M, Yahoo N, Janzen J, Singh I, Fan C, Liu X, Rau M, Feuchtenberger M, Schwaneck E, Wallace SJ, Cockell S, Wilson-Kanamori J, Ramachandran P, Kho C, Kendall TJ, Leblond AL, Keppler SJ, Bielecki P, Steiger K, Hofmann M, Rippe K, Zitzelsberger H, Weber A, Malek N, Luedde T, Vucur M, Augustin HG, Flavell R, Parnas O, Rad R, Pabst O, Henderson NC, Huber S, Macpherson A, Knolle P, Claassen M, Geier A, Trautwein C, Unger K, Elinav E, Waisman A, Abdullah Z, Haller D, Tacke F, Anstee QM, Heikenwalder M. Kotsiliti E, et al. J Hepatol. 2023 Aug;79(2):296-313. doi: 10.1016/j.jhep.2023.04.037. Epub 2023 May 22. J Hepatol. 2023. PMID: 37224925 Free PMC article.
IMPACT AND IMPLICATIONS: There is currently no effective treatment for non-alcoholic steatohepatitis (NASH), which is associated with a substantial healthcare burden and is a growing risk factor for hepatocellular carcinoma (HCC). We have previously shown that NASH is an auto-agg …
IMPACT AND IMPLICATIONS: There is currently no effective treatment for non-alcoholic steatohepatitis (NASH), which is associated with a subs …
PACS-2 deficiency in tubular cells aggravates lipid-related kidney injury in diabetic kidney disease.
Zhao C, Li L, Li C, Tang C, Cai J, Liu Y, Yang J, Xi Y, Yang M, Jiang N, Han Y, Liu Y, Luo S, Xiao L, Sun L. Zhao C, et al. Mol Med. 2022 Sep 23;28(1):117. doi: 10.1186/s10020-022-00545-x. Mol Med. 2022. PMID: 36138342 Free PMC article.
Transfection of HK2 cells with PACS-2 siRNA under high glucose plus palmitic acid (HGPA) condition aggravated lipid deposition and increased the expression of SOAT1 and sterol regulatory element-binding proteins (SREBPs), while the effect was blocked partially in th …
Transfection of HK2 cells with PACS-2 siRNA under high glucose plus palmitic acid (HGPA) condition aggravated lipid deposition …
Real-World Use of Ruxolitinib Cream: Safety Analysis at 1 Year.
Hu W, Thornton M, Livingston RA. Hu W, et al. Am J Clin Dermatol. 2024 Mar;25(2):327-332. doi: 10.1007/s40257-023-00840-1. Epub 2024 Jan 19. Am J Clin Dermatol. 2024. PMID: 38243107 Free PMC article.
., any unfavorable sign, symptom, or disease) representing >2% of all events included application site pain (n = 16), atopic dermatitis (n = 15), skin irritation (n = 15), scratch (n = 14), and condition aggravated (n = 13). The four serious AEs were skin cancer …
., any unfavorable sign, symptom, or disease) representing >2% of all events included application site pain (n = 16), atopic dermatitis ( …
Real-world safety profile of eculizumab in patients with paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, or generalized myasthenia gravis: an integrated analysis of post-marketing surveillance in Japan.
Nishimura JI, Kawaguchi T, Ito S, Murai H, Shimono A, Matsuda T, Fukamizu Y, Akiyama H, Hayashi H, Nakano T, Maruyama S. Nishimura JI, et al. Int J Hematol. 2023 Oct;118(4):419-431. doi: 10.1007/s12185-023-03630-x. Epub 2023 Jul 29. Int J Hematol. 2023. PMID: 37515657
AEs with an incidence of 1.0 per 100 patient-years included hemolysis, headache, nasopharyngitis, renal impairment, anemia, pneumonia, upper respiratory tract inflammation, influenza, condition aggravated, and infection. The incidence of infection-related AEs was 21 …
AEs with an incidence of 1.0 per 100 patient-years included hemolysis, headache, nasopharyngitis, renal impairment, anemia, pneumonia, upper …
Post-marketing safety surveillance of dalfampridine for multiple sclerosis using FDA adverse event reporting system.
Xiong R, Lei J, Pan S, Zhang H, Tong Y, Wu W, Huang Y, Lai X. Xiong R, et al. Front Pharmacol. 2023 Sep 14;14:1226086. doi: 10.3389/fphar.2023.1226086. eCollection 2023. Front Pharmacol. 2023. PMID: 37781705 Free PMC article.
The most frequently reported AE signals were urinary tract infection, dizziness, condition aggravated. In addition, 23 AE signals with death outcomes were identified, with an incidence of less than 0.1%. ...
The most frequently reported AE signals were urinary tract infection, dizziness, condition aggravated. In addition, 23 AE sign …
Post-Marketing Safety Surveillance of Tofacitinib over 9 Years in Patients with Psoriatic Arthritis and Rheumatoid Arthritis.
Burmester GR, Coates LC, Cohen SB, Tanaka Y, Vranic I, Nagy E, Lazariciu I, Chen AS, Kwok K, Fallon L, Kinch C. Burmester GR, et al. Rheumatol Ther. 2023 Oct;10(5):1255-1276. doi: 10.1007/s40744-023-00576-8. Epub 2023 Jul 17. Rheumatol Ther. 2023. PMID: 37458964 Free PMC article.
The most frequently-reported AE Preferred Terms (PsA/RA) included drug ineffective (20.0%/17.8%), pain (9.7%/10.6%), condition aggravated (9.9%/10.5%), headache (8.8%/7.9%) and, for PsA, off-label use (10.5%/3.4%). ...
The most frequently-reported AE Preferred Terms (PsA/RA) included drug ineffective (20.0%/17.8%), pain (9.7%/10.6%), condition agg …
[Research progress on cirrhosis reversal and recompensation].
Xu JH, Yu YY, Xu XY. Xu JH, et al. Zhonghua Gan Zang Bing Za Zhi. 2023 Jul 20;31(7):673-676. doi: 10.3760/cma.j.cn501113-20230513-00220. Zhonghua Gan Zang Bing Za Zhi. 2023. PMID: 37580245 Chinese.
Previously, liver lesions in cirrhosis were considered irreversible, especially because the condition aggravated gradually after entering the decompensated phase, thus making it difficult to return to the compensated phase. ...
Previously, liver lesions in cirrhosis were considered irreversible, especially because the condition aggravated gradually aft …
A real-world disproportionality analysis of mesalazine data mining of the public version of FDA adverse event reporting system.
Liu M, Gu L, Zhang Y, Zhou H, Wang Y, Xu ZX. Liu M, et al. Front Pharmacol. 2024 Jan 31;15:1290975. doi: 10.3389/fphar.2024.1290975. eCollection 2024. Front Pharmacol. 2024. PMID: 38357304 Free PMC article.
The most common AEs included colitis ulcerative, diarrhoea, condition aggravated, crohn's disease, fatigue, abdominal pain, nausea, haematochezia, which were corresponding to those reported in the specification and clinical trials. ...
The most common AEs included colitis ulcerative, diarrhoea, condition aggravated, crohn's disease, fatigue, abdominal pain, na …
[Occupational dermatoses: management for general practitioners and an interdisciplinary collaboration model].
Turcu V, Seremet Caplanusi T, Kokkinakis I, Crepy MN, Zyska Cherix A, Rast H, Krief P. Turcu V, et al. Rev Med Suisse. 2022 Jun 29;18(788):1322-1328. doi: 10.53738/REVMED.2022.18.788.1322. Rev Med Suisse. 2022. PMID: 35770436 French.
Nevertheless, there is an under-reporting of occupational diseases and the management of patients with either a possible occupational dermatosis or a condition aggravated by work which could be improved. The aim of this article is to present the most common occupati …
Nevertheless, there is an under-reporting of occupational diseases and the management of patients with either a possible occupational dermat …
Effect of High-salt Consumption on Rodent Gut Microbiome: A Meta-Analysis.
Towhid ST. Towhid ST. Mymensingh Med J. 2019 Jul;28(3):567-573. Mymensingh Med J. 2019. PMID: 31391428
The outcomes of this meta-analysis indicates the dependence of mammalian gut microbiome on the amount of salt ingested, a condition aggravated by the global climate change and therefore necessitates similar studies on human populations living on coastal areas....
The outcomes of this meta-analysis indicates the dependence of mammalian gut microbiome on the amount of salt ingested, a condition …
42 results