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Results: 7

1.

Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target.

Harb JG, Neviani P, Chyla BJ, Ellis JJ, Ferenchak GJ, Oaks JJ, Walker CJ, Hokland P, Roy DC, Caligiuri MA, Marcucci G, Huettner CS, Perrotti D.

Leukemia. 2013 Oct;27(10):1996-2005. doi: 10.1038/leu.2013.151. Epub 2013 May 14.

PMID:
23670294
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer.

Rudin CM, Hann CL, Garon EB, Ribeiro de Oliveira M, Bonomi PD, Camidge DR, Chu Q, Giaccone G, Khaira D, Ramalingam SS, Ranson MR, Dive C, McKeegan EM, Chyla BJ, Dowell BL, Chakravartty A, Nolan CE, Rudersdorf N, Busman TA, Mabry MH, Krivoshik AP, Humerickhouse RA, Shapiro GI, Gandhi L.

Clin Cancer Res. 2012 Jun 1;18(11):3163-9. doi: 10.1158/1078-0432.CCR-11-3090. Epub 2012 Apr 11.

PMID:
22496272
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence.

Fischer MA, Moreno-Miralles I, Hunt A, Chyla BJ, Hiebert SW.

EMBO J. 2012 Mar 21;31(6):1494-505. doi: 10.1038/emboj.2011.500. Epub 2012 Jan 20.

PMID:
22266796
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation.

Chyla BJ, Moreno-Miralles I, Steapleton MA, Thompson MA, Bhaskara S, Engel M, Hiebert SW.

Mol Cell Biol. 2008 Oct;28(20):6234-47. doi: 10.1128/MCB.00404-08. Epub 2008 Aug 18.

PMID:
18710942
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control.

Bhaskara S, Chyla BJ, Amann JM, Knutson SK, Cortez D, Sun ZW, Hiebert SW.

Mol Cell. 2008 Apr 11;30(1):61-72. doi: 10.1016/j.molcel.2008.02.030.

PMID:
18406327
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks.

Knutson SK, Chyla BJ, Amann JM, Bhaskara S, Huppert SS, Hiebert SW.

EMBO J. 2008 Apr 9;27(7):1017-28. doi: 10.1038/emboj.2008.51. Epub 2008 Mar 20.

PMID:
18354499
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine.

Amann JM, Chyla BJ, Ellis TC, Martinez A, Moore AC, Franklin JL, McGhee L, Meyers S, Ohm JE, Luce KS, Ouelette AJ, Washington MK, Thompson MA, King D, Gautam S, Coffey RJ, Whitehead RH, Hiebert SW.

Mol Cell Biol. 2005 Nov;25(21):9576-85.

PMID:
16227606
[PubMed - indexed for MEDLINE]
Free PMC Article

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