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Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.

Zhao Y, Banerjee S, Dey N, LeJeune WS, Sarkar PS, Brobey R, Rosenblatt KP, Tilton RG, Choudhary S.

Diabetes. 2011 Jul;60(7):1907-16. doi: 10.2337/db10-1262. Epub 2011 May 18.


Vimentin is a novel AKT1 target mediating motility and invasion.

Zhu QS, Rosenblatt K, Huang KL, Lahat G, Brobey R, Bolshakov S, Nguyen T, Ding Z, Belousov R, Bill K, Luo X, Lazar A, Dicker A, Mills GB, Hung MC, Lev D.

Oncogene. 2011 Jan 27;30(4):457-70. doi: 10.1038/onc.2010.421. Epub 2010 Sep 20.


The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging.

Hsieh CC, Kuro-o M, Rosenblatt KP, Brobey R, Papaconstantinou J.

Aging (Albany NY). 2010 Sep;2(9):597-611.

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