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Items: 1 to 20 of 43


Protein folding. Translational tuning optimizes nascent protein folding in cells.

Kim SJ, Yoon JS, Shishido H, Yang Z, Rooney LA, Barral JM, Skach WR.

Science. 2015 Apr 24;348(6233):444-8. doi: 10.1126/science.aaa3974.


Thermally-induced structural changes in an armadillo repeat protein suggest a novel thermosensor mechanism in a molecular chaperone.

Bujalowski PJ, Nicholls P, Barral JM, Oberhauser AF.

FEBS Lett. 2015 Jan 2;589(1):123-30. doi: 10.1016/j.febslet.2014.11.034. Epub 2014 Nov 29.


Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke.

Nicholls P, Bujalowski PJ, Epstein HF, Boehning DF, Barral JM, Oberhauser AF.

FEBS Lett. 2014 Nov 3;588(21):3977-81. doi: 10.1016/j.febslet.2014.09.013. Epub 2014 Sep 19.


Non-optimal codon usage affects expression, structure and function of clock protein FRQ.

Zhou M, Guo J, Cha J, Chae M, Chen S, Barral JM, Sachs MS, Liu Y.

Nature. 2013 Mar 7;495(7439):111-5. doi: 10.1038/nature11833. Epub 2013 Feb 17.


Ubiquilin-1 and protein quality control in Alzheimer disease.

El Ayadi A, Stieren ES, Barral JM, Boehning D.

Prion. 2013 Mar-Apr;7(2):164-9. doi: 10.4161/pri.23711. Epub 2013 Jan 29.


Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release.

Akimzhanov AM, Barral JM, Boehning D.

Cell Calcium. 2013 Feb;53(2):152-8. doi: 10.1016/j.ceca.2012.10.002. Epub 2012 Nov 2.


Purification and aggregation of the amyloid precursor protein intracellular domain.

El Ayadi A, Stieren ES, Barral JM, Oberhauser AF, Boehning D.

J Vis Exp. 2012 Aug 28;(66):e4204. doi: 10.3791/4204.


Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688.

El Ayadi A, Stieren ES, Barral JM, Boehning D.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13416-21. doi: 10.1073/pnas.1206786109. Epub 2012 Jul 30.


Silent substitutions predictably alter translation elongation rates and protein folding efficiencies.

Spencer PS, Siller E, Anderson JF, Barral JM.

J Mol Biol. 2012 Sep 21;422(3):328-35. doi: 10.1016/j.jmb.2012.06.010. Epub 2012 Jun 12.


Genetic code redundancy and its influence on the encoded polypeptides.

Spencer PS, Barral JM.

Comput Struct Biotechnol J. 2012 Mar 20;1:e201204006. doi: 10.5936/csbj.201204006. eCollection 2012. Review.


Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein.

Stieren ES, El Ayadi A, Xiao Y, Siller E, Landsverk ML, Oberhauser AF, Barral JM, Boehning D.

J Biol Chem. 2011 Oct 14;286(41):35689-98. doi: 10.1074/jbc.M111.243147. Epub 2011 Aug 18.


The neurodegenerative-disease-related protein sacsin is a molecular chaperone.

Anderson JF, Siller E, Barral JM.

J Mol Biol. 2011 Aug 26;411(4):870-80. doi: 10.1016/j.jmb.2011.06.016. Epub 2011 Jun 25.


Disorders of protein biogenesis and stability.

Anderson JF, Siller E, Barral JM.

Protein Pept Lett. 2011 Feb;18(2):110-21. Review.


The sacsin repeating region (SRR): a novel Hsp90-related supra-domain associated with neurodegeneration.

Anderson JF, Siller E, Barral JM.

J Mol Biol. 2010 Jul 23;400(4):665-74. doi: 10.1016/j.jmb.2010.05.023. Epub 2010 May 19. Review.


Post-burn hepatic insulin resistance is associated with endoplasmic reticulum (ER) stress.

Gauglitz GG, Halder S, Boehning DF, Kulp GA, Herndon DN, Barral JM, Jeschke MG.

Shock. 2010 Mar;33(3):299-305. doi: 10.1097/SHK.0b013e3181b2f439.


Calcium and ER stress mediate hepatic apoptosis after burn injury.

Jeschke MG, Gauglitz GG, Song J, Kulp GA, Finnerty CC, Cox RA, Barral JM, Herndon DN, Boehning D.

J Cell Mol Med. 2009 Aug;13(8B):1857-65. doi: 10.1111/j.1582-4934.2009.00644.x.


Slowing bacterial translation speed enhances eukaryotic protein folding efficiency.

Siller E, DeZwaan DC, Anderson JF, Freeman BC, Barral JM.

J Mol Biol. 2010 Mar 12;396(5):1310-8. doi: 10.1016/j.jmb.2009.12.042. Epub 2010 Jan 4.


Clinical significance of V617F mutation of the JAK2 gene in patients with chronic myeloproliferative disorders.

Basquiera AL, Soria NW, Ryser R, Salguero M, Moiraghi B, Sackmann F, Sturich AG, Borello A, Berretta A, Bonafé M, Barral JM, Palazzo ED, García JJ.

Hematology. 2009 Dec;14(6):323-30. doi: 10.1179/102453309X12473408860226.


Characterization of the inflammatory response during acute and post-acute phases after severe burn.

Gauglitz GG, Song J, Herndon DN, Finnerty CC, Boehning D, Barral JM, Jeschke MG.

Shock. 2008 Nov;30(5):503-7. doi: 10.1097/SHK.0b013e31816e3373.


Requirement of inositol 1,4,5-trisphosphate receptors for tumor-mediated lymphocyte apoptosis.

Steinmann C, Landsverk ML, Barral JM, Boehning D.

J Biol Chem. 2008 May 16;283(20):13506-9. doi: 10.1074/jbc.C800029200. Epub 2008 Mar 25.

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