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Achieving high-sensitivity for clinical applications using augmented exome sequencing.

Patwardhan A, Harris J, Leng N, Bartha G, Church DM, Luo S, Haudenschild C, Pratt M, Zook J, Salit M, Tirch J, Morra M, Chervitz S, Li M, Clark M, Garcia S, Chandratillake G, Kirk S, Ashley E, Snyder M, Altman R, Bustamante C, Butte AJ, West J, Chen R.

Genome Med. 2015 Jul 16;7(1):71. doi: 10.1186/s13073-015-0197-4. eCollection 2015.


A Rapid, High-Quality, Cost-Effective, Comprehensive, and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases.

Wilson KD, Shen P, Fung E, Karakikes I, Zhang A, InanlooRahatloo K, Odegaard J, Sallam K, Davis RW, Lui G, Ashley E, Scharfe C, Wu JC.

Circ Res. 2015 Aug 11. pii: CIRCRESAHA.115.306723. [Epub ahead of print]


When Medical News Comes from Press Releases-A Case Study of Pancreatic Cancer and Processed Meat.

Taylor JW, Long M, Ashley E, Denning A, Gout B, Hansen K, Huws T, Jennings L, Quinn S, Sarkies P, Wojtowicz A, Newton PM.

PLoS One. 2015 Jun 17;10(6):e0127848. doi: 10.1371/journal.pone.0127848. eCollection 2015.


Systematic Comparison of Digital Electrocardiograms From Healthy Athletes and Patients With Hypertrophic Cardiomyopathy.

Bent RE, Wheeler MT, Hadley D, Knowles JW, Pavlovic A, Finocchiaro G, Haddad F, Salisbury H, Race S, Shmargad Y, Matheson GO, Kumar N, Saini D, Froelicher V, Ashley E, Perez MV.

J Am Coll Cardiol. 2015 Jun 9;65(22):2462-3. doi: 10.1016/j.jacc.2015.03.559. No abstract available.


Limitations of Current AHA Guidelines and Proposal of New Guidelines for the Preparticipation Examination of Athletes.

Dunn TP, Pickham D, Aggarwal S, Saini D, Kumar N, Wheeler MT, Perez M, Ashley E, Froelicher VF.

Clin J Sport Med. 2015 Apr 24. [Epub ahead of print]


The impact of chronic endurance and resistance training upon the right ventricular phenotype in male athletes.

Utomi V, Oxborough D, Ashley E, Lord R, Fletcher S, Stembridge M, Shave R, Hoffman MD, Whyte G, Somauroo J, Sharma S, George K.

Eur J Appl Physiol. 2015 Aug;115(8):1673-82. doi: 10.1007/s00421-015-3147-3. Epub 2015 Mar 17.


Computerized Q wave dimensions in athletes and hypertrophic cardiomyopathy patients.

Bent RE, Wheeler MT, Hadley D, Froelicher V, Ashley E, Perez MV.

J Electrocardiol. 2015 May-Jun;48(3):362-7. doi: 10.1016/j.jelectrocard.2015.01.009. Epub 2015 Feb 14.


Prevalence and prognostic role of right ventricular involvement in stress-induced cardiomyopathy.

Finocchiaro G, Kobayashi Y, Magavern E, Zhou JQ, Ashley E, Sinagra G, Schnittger I, Knowles JW, Fearon WF, Haddad F, Tremmel JA.

J Card Fail. 2015 May;21(5):419-25. doi: 10.1016/j.cardfail.2015.02.001. Epub 2015 Feb 19.


Klebsiella pneumoniae Infection: A Virulent Cause of Visual Loss.

Soon WC, Pouncey A, Ashley E, Bowen EF.

Case Rep Ophthalmol. 2014 Dec 19;5(3):468-73. doi: 10.1159/000370145. eCollection 2014 Sep-Dec.


Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations.

Coppini R, Ho CY, Ashley E, Day S, Ferrantini C, Girolami F, Tomberli B, Bardi S, Torricelli F, Cecchi F, Mugelli A, Poggesi C, Tardiff J, Olivotto I.

J Am Coll Cardiol. 2014 Dec 23;64(24):2589-600. doi: 10.1016/j.jacc.2014.09.059.


Additive prognostic value of a cardiopulmonary exercise test score in patients with heart failure and intermediate risk.

Ritt LE, Myers J, Stein R, Arena R, Guazzi M, Chase P, Bensimhon D, Ashley E, Cahalin LP, Forman DE.

Int J Cardiol. 2015 Jan 15;178:262-4. doi: 10.1016/j.ijcard.2014.10.025. Epub 2014 Oct 12. No abstract available.


Artemisinin resistance--modelling the potential human and economic costs.

Lubell Y, Dondorp A, Guérin PJ, Drake T, Meek S, Ashley E, Day NP, White NJ, White LJ.

Malar J. 2014 Nov 23;13:452. doi: 10.1186/1475-2875-13-452.


The right ventricle following ultra-endurance exercise: insights from novel echocardiography and 12-lead electrocardiography.

Lord R, Somauroo J, Stembridge M, Jain N, Hoffman MD, George K, Jones H, Shave R, Haddad F, Ashley E, Oxborough D.

Eur J Appl Physiol. 2015 Jan;115(1):71-80. doi: 10.1007/s00421-014-2995-6. Epub 2014 Sep 10.


A long noncoding RNA protects the heart from pathological hypertrophy.

Han P, Li W, Lin CH, Yang J, Shang C, Nurnberg ST, Jin KK, Xu W, Lin CY, Lin CJ, Xiong Y, Chien HC, Zhou B, Ashley E, Bernstein D, Chen PS, Chen HS, Quertermous T, Chang CP.

Nature. 2014 Oct 2;514(7520):102-6. doi: 10.1038/nature13596. Epub 2014 Aug 10.


Identification of a new target of miR-16, Vacuolar Protein Sorting 4a.

Adhikari N, Guan W, Capaldo B, Mackey AJ, Carlson M, Ramakrishnan S, Walek D, Gupta M, Mitchell A, Eckman P, John R, Ashley E, Barton PJ, Hall JL.

PLoS One. 2014 Jul 17;9(7):e101509. doi: 10.1371/journal.pone.0101509. eCollection 2014.


Interpreting whole-genome sequencing--reply.

Dewey F, Ashley E, Quertermous T.

JAMA. 2014 Jul 16;312(3):296-7. doi: 10.1001/jama.2014.6605. No abstract available.


Plasma and urine neutrophil gelatinase-associated lipocalin in the diagnosis of new onset acute kidney injury in critically ill patients.

Matsa R, Ashley E, Sharma V, Walden AP, Keating L.

Crit Care. 2014 Jul 1;18(4):R137. doi: 10.1186/cc13958.


Predominance of normal left ventricular geometry in the male 'athlete's heart'.

Utomi V, Oxborough D, Ashley E, Lord R, Fletcher S, Stembridge M, Shave R, Hoffman MD, Whyte G, Somauroo J, Sharma S, George K.

Heart. 2014 Aug;100(16):1264-71. doi: 10.1136/heartjnl-2014-305904. Epub 2014 Jun 10.


Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension.

de Jesus Perez VA, Yuan K, Lyuksyutova MA, Dewey F, Orcholski ME, Shuffle EM, Mathur M, Yancy L Jr, Rojas V, Li CG, Cao A, Alastalo TP, Khazeni N, Cimprich KA, Butte AJ, Ashley E, Zamanian RT.

Am J Respir Crit Care Med. 2014 May 15;189(10):1260-72. doi: 10.1164/rccm.201310-1749OC.


Effects of respiratory exchange ratio on the prognostic value of peak oxygen consumption and ventilatory efficiency in patients with systolic heart failure.

Chase PJ, Kenjale A, Cahalin LP, Arena R, Davis PG, Myers J, Guazzi M, Forman DE, Ashley E, Peberdy MA, West E, Kelly CT, Bensimhon DR.

JACC Heart Fail. 2013 Oct;1(5):427-32. doi: 10.1016/j.jchf.2013.05.008. Epub 2013 Sep 11.

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