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Items: 1 to 20 of 64

1.

Gli as a novel therapeutic target in malignant pleural mesothelioma.

Li H, Lui N, Cheng T, Tseng HH, Yue D, Giroux-Leprieur E, Do HT, Sheng Q, Jin JQ, Luh TW, Jablons DM, He B.

PLoS One. 2013;8(3):e57346. doi: 10.1371/journal.pone.0057346. Epub 2013 Mar 6.

2.

Vismodegib, a small-molecule inhibitor of the hedgehog pathway for the treatment of advanced cancers.

De Smaele E, Ferretti E, Gulino A.

Curr Opin Investig Drugs. 2010 Jun;11(6):707-18. Review.

PMID:
20496266
3.

Pemetrexed: a multitargeted antifolate.

Rollins KD, Lindley C.

Clin Ther. 2005 Sep;27(9):1343-82. Review.

PMID:
16291410
4.

Hedgehog signaling pathway and cancer therapeutics: progress to date.

Ruch JM, Kim EJ.

Drugs. 2013 May;73(7):613-23. doi: 10.1007/s40265-013-0045-z. Review.

PMID:
23605693
5.

Hedgehog fights back: mechanisms of acquired resistance against Smoothened antagonists.

Metcalfe C, de Sauvage FJ.

Cancer Res. 2011 Aug 1;71(15):5057-61. doi: 10.1158/0008-5472.CAN-11-0923. Epub 2011 Jul 19. Review. Erratum in: Cancer Res. 2011 Sep 15;71(18):6087.

6.

Second-line treatment for malignant pleural mesothelioma.

Ceresoli GL, Zucali PA, Gianoncelli L, Lorenzi E, Santoro A.

Cancer Treat Rev. 2010 Feb;36(1):24-32. doi: 10.1016/j.ctrv.2009.09.003. Epub 2009 Oct 29. Review.

PMID:
19879055
7.

Targeting GLI factors to inhibit the Hedgehog pathway.

Infante P, Alfonsi R, Botta B, Mori M, Di Marcotullio L.

Trends Pharmacol Sci. 2015 Aug;36(8):547-58. doi: 10.1016/j.tips.2015.05.006. Epub 2015 Jun 10. Review.

PMID:
26072120
8.
9.

Antiangiogenic therapies for malignant pleural mesothelioma.

Yano S, Li Q, Wang W, Yamada T, Takeuchi S, Nakataki E, Ogino H, Goto H, Nishioka Y, Sone S.

Front Biosci (Landmark Ed). 2011 Jan 1;16:740-8. Review.

PMID:
21196199
10.

Vismodegib: an inhibitor of the Hedgehog signaling pathway in the treatment of basal cell carcinoma.

Proctor AE, Thompson LA, O'Bryant CL.

Ann Pharmacother. 2014 Jan;48(1):99-106. doi: 10.1177/1060028013506696. Epub 2013 Oct 15. Review.

PMID:
24259609
11.

Targeting the hedgehog pathway to treat basal cell carcinoma.

Geeraert P, Williams JS, Brownell I.

J Drugs Dermatol. 2013 May;12(5):519-23. Review.

PMID:
23652945
12.

Locally advanced and metastatic basal cell carcinoma: molecular pathways, treatment options and new targeted therapies.

Ruiz Salas V, Alegre M, Garcés JR, Puig L.

Expert Rev Anticancer Ther. 2014 Jun;14(6):741-9. doi: 10.1586/14737140.2014.895326. Epub 2014 Mar 10. Review.

PMID:
24611655
13.

The role of epigenetics in malignant pleural mesothelioma.

Vandermeers F, Neelature Sriramareddy S, Costa C, Hubaux R, Cosse JP, Willems L.

Lung Cancer. 2013 Sep;81(3):311-8. doi: 10.1016/j.lungcan.2013.05.014. Epub 2013 Jun 18. Review.

PMID:
23790315
14.

Nonclassical hedgehog-GLI signaling and its clinical implications.

Shevde LA, Samant RS.

Int J Cancer. 2014 Jul 1;135(1):1-6. doi: 10.1002/ijc.28424. Epub 2013 Sep 11. Review.

15.

Vismodegib.

Meiss F, Zeiser R.

Recent Results Cancer Res. 2014;201:405-17. doi: 10.1007/978-3-642-54490-3_25. Review.

PMID:
24756807
16.

Anti-angiogenic therapies for malignant pleural mesothelioma.

Ceresoli GL, Zucali PA.

Expert Opin Investig Drugs. 2012 Jun;21(6):833-44. doi: 10.1517/13543784.2012.681641. Epub 2012 Apr 23. Review.

PMID:
22519641
17.

Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened.

Gonnissen A, Isebaert S, Haustermans K.

Oncotarget. 2015 Jun 10;6(16):13899-913. Review.

18.

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy.

Lauth M, Toftgård R.

Cell Cycle. 2007 Oct 15;6(20):2458-63. Epub 2007 Jul 30. Review.

PMID:
17726373
19.

Histone deacetylase inhibitors in malignant pleural mesothelioma: preclinical rationale and clinical trials.

Paik PK, Krug LM.

J Thorac Oncol. 2010 Feb;5(2):275-9. doi: 10.1097/JTO.0b013e3181c5e366. Review.

20.

Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy.

Pandolfi S, Stecca B.

Expert Rev Mol Med. 2015 Feb 9;17:e5. doi: 10.1017/erm.2015.3. Review.

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